User:Tkadm30/Notebook/Endocannabinoids: Difference between revisions
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== | == Notes == | ||
=== | === Hypothesis === | ||
DHA induced FAAH hydrolysis may promote neurogenesis via CB1 activation. | |||
=== | === Model === | ||
# Use omega 3 (DHA) fatty acids as substrate for anandamide hydrolysis | # Use omega 3 (DHA) fatty acids as substrate for anandamide hydrolysis | ||
# Protect the hippocampus and neurons from stress induced damage. | # Protect the hippocampus and neurons from stress induced damage. | ||
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* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/ | * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/ | ||
* http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035504/ | * http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035504/ | ||
* http://www.ncbi.nlm.nih.gov/pubmed/22959887 | |||
CB1 signaling and memory: | CB1 signaling and memory: | ||
Revision as of 06:36, 27 September 2014
Notes
Hypothesis
DHA induced FAAH hydrolysis may promote neurogenesis via CB1 activation.
Model
- Use omega 3 (DHA) fatty acids as substrate for anandamide hydrolysis
- Protect the hippocampus and neurons from stress induced damage.
Documentation
Protocol:
- http://www.ncbi.nlm.nih.gov/pubmed/23103355
- http://www.ncbi.nlm.nih.gov/pubmed/11470906
- http://www.ncbi.nlm.nih.gov/pubmed/9842734/
- http://www.ncbi.nlm.nih.gov/pubmed/15111006/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1253627/
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035504/
- http://www.ncbi.nlm.nih.gov/pubmed/22959887
CB1 signaling and memory:
- http://www.ncbi.nlm.nih.gov/pubmed/24648181
- Cannabinoids and hippocampal neurogenesis:
DHA:
Anandamide signaling:
FAAH (fatty acid amide hydrolase):
Introduction to fatty amides:
Keywords
hippocampus, anandamide, FAAH, fatty acids, THC, neurogenesis
