User:Etienne Robillard/Notebook/Drospirenone - Revision history

Etienne Robillard at 01:36, 5 February 2013

Etienne Robillard — Tue, 05 Feb 2013 01:36:49 GMT

←Older revision		Revision as of 01:36, 5 February 2013
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	* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?		* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]
-	* Ethics of birth control with chiral Schiff base ~~alkyloids~~ in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .	+	* Ethics of birth control with chiral Schiff base alkaloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .

	=== Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone) ===		=== Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone) ===
-	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected [~~https~~://en.wikipedia.org/wiki/Alkaloid#Synthesis_of_Schiff_bases alkaloids] via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]	+	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected [http://en.wikipedia.org/wiki/Alkaloid#Synthesis_of_Schiff_bases alkaloids] via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]

	== References ==		== References ==

Etienne Robillard: /* Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone) */

Etienne Robillard — Tue, 05 Feb 2013 01:33:38 GMT

Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone)

←Older revision		Revision as of 01:33, 5 February 2013
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	=== Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone) ===		=== Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone) ===
-	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected ~~alkyloids~~ via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]	+	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected [https://en.wikipedia.org/wiki/Alkaloid#Synthesis_of_Schiff_bases alkaloids] via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]

	== References ==		== References ==

Etienne Robillard at 01:03, 5 February 2013

Etienne Robillard — Tue, 05 Feb 2013 01:03:11 GMT

←Older revision		Revision as of 01:03, 5 February 2013
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	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]
	* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .		* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
		+
		+	=== Yb(OTf)3-catalyzed synthetic pyrrolidines via aldimine-protected analogs (Drosperinone) ===
	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected alkyloids via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]		* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected alkyloids via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]

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	# [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters]		# [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters]
	# http://en.wikipedia.org/wiki/Ketoxime		# http://en.wikipedia.org/wiki/Ketoxime
-		+	# http://en.wikipedia.org/wiki/Aldimine

	== See also ==		== See also ==

Etienne Robillard at 16:50, 4 February 2013

Etienne Robillard — Mon, 04 Feb 2013 16:50:38 GMT

←Older revision		Revision as of 16:50, 4 February 2013
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	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]
	* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .		* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
-	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected ~~alkylamines~~ via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3]]	+	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected alkyloids via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3], [http://repository.ias.ac.in/62840/ 4]]

	== References ==		== References ==
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	# http://en.wikipedia.org/wiki/Spironolactone		# http://en.wikipedia.org/wiki/Spironolactone
	# [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters]		# [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters]
-		+	# http://en.wikipedia.org/wiki/Ketoxime


	== See also ==		== See also ==

-	[[Pyrrolidines]]	+	* [[Pyrrolidines]]
		+	* [http://en.wikipedia.org/wiki/Beckmann_rearrangement Beckman rearrangement]

Etienne Robillard at 15:57, 4 February 2013

Etienne Robillard — Mon, 04 Feb 2013 15:57:36 GMT

←Older revision		Revision as of 15:57, 4 February 2013
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	* CYP450 mediated [1] (A spironolactone derived alkyloid)		* CYP450 mediated [1] (A spironolactone derived alkyloid)
	* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?		* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
-	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]	+	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]
	* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .		* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
-	* Hence, is there a Yb(OTf)3 (diastereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? ~~See~~ [http://www.organic-chemistry.org/abstracts/literature/979.shtm ~~Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)~~3 ~~Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters~~	+	* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3]]
-	]	+
-		+
-		+

	== References ==		== References ==
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	# http://en.wikipedia.org/wiki/Drospirenone		# http://en.wikipedia.org/wiki/Drospirenone
	# http://en.wikipedia.org/wiki/Spironolactone		# http://en.wikipedia.org/wiki/Spironolactone
		+	# [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters]
		+
		+

	== See also ==		== See also ==

	[[Pyrrolidines]]		[[Pyrrolidines]]

Etienne Robillard at 15:47, 4 February 2013

Etienne Robillard — Mon, 04 Feb 2013 15:47:56 GMT

←Older revision		Revision as of 15:47, 4 February 2013
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	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]
	* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .		* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
-	* Hence, is there a Yb(OTf)3 (~~distereoselective~~) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? See http://www.organic-chemistry.org/abstracts/literature/979.shtm	+	* Hence, is there a Yb(OTf)3 (diastereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? See [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters
		+	]

Etienne Robillard at 15:45, 4 February 2013

Etienne Robillard — Mon, 04 Feb 2013 15:45:55 GMT

←Older revision		Revision as of 15:45, 4 February 2013
Line 2:		Line 2:
	* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?		* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]
-	* Ethics of birth control with chiral ~~schiff~~ base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .	+	* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
		+	* Hence, is there a Yb(OTf)3 (distereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? See http://www.organic-chemistry.org/abstracts/literature/979.shtm
		+
		+

	== References ==		== References ==
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	# http://en.wikipedia.org/wiki/Drospirenone		# http://en.wikipedia.org/wiki/Drospirenone
	# http://en.wikipedia.org/wiki/Spironolactone		# http://en.wikipedia.org/wiki/Spironolactone
		+
		+	== See also ==
		+
		+	[[Pyrrolidines]]

Etienne Robillard at 15:10, 4 February 2013

Etienne Robillard — Mon, 04 Feb 2013 15:10:12 GMT

←Older revision		Revision as of 15:10, 4 February 2013
Line 2:		Line 2:
	* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?		* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]
-	* Ethics of birth control with chiral schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [[http://en.wikipedia.org/wiki/Grignard_reagent\|Grignard reagent]]	+	* Ethics of birth control with chiral schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .

	== References ==		== References ==

Etienne Robillard at 15:08, 4 February 2013

Etienne Robillard — Mon, 04 Feb 2013 15:08:46 GMT

←Older revision		Revision as of 15:08, 4 February 2013
Line 2:		Line 2:
	* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?		* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
	* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]		* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]
		+	* Ethics of birth control with chiral schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [[http://en.wikipedia.org/wiki/Grignard_reagent\|Grignard reagent]]

	== References ==		== References ==

Etienne Robillard: New page: * CYP450 mediated [1] (A spironolactone derived alkyloid) * optical isomerism (C2) : a HSL (homoserine) lactone derivative ? * A high risks of hyperkalemia (K+) was found with long-term us...

Etienne Robillard — Mon, 04 Feb 2013 14:19:16 GMT

New page: * CYP450 mediated [1] (A spironolactone derived alkyloid) * optical isomerism (C2) : a HSL (homoserine) lactone derivative ? * A high risks of hyperkalemia (K+) was found with long-term us...

New page

* CYP450 mediated [1] (A spironolactone derived alkyloid)
* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]

== References ==

# http://en.wikipedia.org/wiki/Drospirenone
# http://en.wikipedia.org/wiki/Spironolactone