User:Tkadm30/Notebook/Drospirenone

• CYP450 mediated [1] (A spironolactone derived alkyloid)
• optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
• A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. 2
• Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See Grignard reagent .
• Hence, is there a Yb(OTf)3 (distereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? See http://www.organic-chemistry.org/abstracts/literature/979.shtm

References

1. http://en.wikipedia.org/wiki/Drospirenone
2. http://en.wikipedia.org/wiki/Spironolactone

See also

Pyrrolidines