User:Etienne Robillard/Notebook/Drospirenone

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* CYP450 mediated [1] (A spironolactone derived alkyloid)
* CYP450 mediated [1] (A spironolactone derived alkyloid)
* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
* optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
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* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]
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* A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [[http://sante.canoe.ca/drug_info_details.asp?brand_name_id=2052 2]]
* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
* Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See [http://en.wikipedia.org/wiki/Grignard_reagent Grignard reagent] .
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* Hence, is there a Yb(OTf)3 (diastereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? See [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters
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* Hence, is there a '''Yb(OTf)3''' (diastereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [[http://www.organic-chemistry.org/abstracts/literature/979.shtm 3]]
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== References ==
== References ==
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# http://en.wikipedia.org/wiki/Drospirenone
# http://en.wikipedia.org/wiki/Drospirenone
# http://en.wikipedia.org/wiki/Spironolactone
# http://en.wikipedia.org/wiki/Spironolactone
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# [http://www.organic-chemistry.org/abstracts/literature/979.shtm Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters]
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== See also ==
== See also ==
[[Pyrrolidines]]
[[Pyrrolidines]]

Revision as of 11:57, 4 February 2013

  • CYP450 mediated [1] (A spironolactone derived alkyloid)
  • optical isomerism (C2) : a HSL (homoserine) lactone derivative ?
  • A high risks of hyperkalemia (K+) was found with long-term use of Yasmin. [2]
  • Ethics of birth control with chiral Schiff base alkyloids in orthogonal Fmoc-carbonyl nucleophilic catalysis? See Grignard reagent .
  • Hence, is there a Yb(OTf)3 (diastereoselective) route to remote activation of Fmoc-protected alkylamines via MW catalysis of C(2)-symmetric amines, ie Drospirenone ? [3]

References

  1. http://en.wikipedia.org/wiki/Drospirenone
  2. http://en.wikipedia.org/wiki/Spironolactone
  3. Diastereoselective Synthesis of Pyrrolidines via the Yb(OTf)3 Catalyzed Three-Component Reaction of Aldehydes, Amines, and 1,1-Cyclopropanediesters


See also

Pyrrolidines

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