User:Tkadm30/Notebook/Arylcyclohexylamines/2013/05/24: Difference between revisions
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* potassium chloride = KCl (anhydrous) [Cl-] | * potassium chloride = KCl (anhydrous) [Cl-] | ||
* KCl (-) mediated CREB1 gene expression: ($35.95) | * KCl (-) mediated CREB1 gene expression: ($35.95) | ||
* Keywords: [http://www.genome.jp/dbget-bin/www_bget?ko:K05870 CREB1], NMDA, potassium chloride, CaM kinase, striatal neurons, dizocilpine | |||
* | * See also: [http://openwetware.org/wiki/User:Etienne_Robillard/Notebook/NMDA_dependent_cell_adhesion NMDA dependent cell adhesion] (aka "calcium binding"). | ||
=== Orthogonal serine/threonine-specific GSK-3 inhibitors === | === Orthogonal serine/threonine-specific GSK-3 inhibitors === | ||
* i found this paper worth the mention (2013): http://www.sciencedirect.com/science/article/pii/S0092867413002857 ($31.50) | * i found this paper worth the mention (2013): http://www.sciencedirect.com/science/article/pii/S0092867413002857 ($31.50) | ||
* c-fos: http://www.uniprot.org/uniprot/P01100 | * c-fos: http://www.uniprot.org/uniprot/P01100 | ||
* CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468 | * CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468 |
Revision as of 08:29, 12 July 2013
A jolie passage
- Calcium chloride (CaCl2) != potassium chloride [Ca2+]
- potassium chloride = food additive
- potassium chloride = KCl (anhydrous) [Cl-]
- KCl (-) mediated CREB1 gene expression: ($35.95)
- Keywords: CREB1, NMDA, potassium chloride, CaM kinase, striatal neurons, dizocilpine
- See also: NMDA dependent cell adhesion (aka "calcium binding").
Orthogonal serine/threonine-specific GSK-3 inhibitors
- i found this paper worth the mention (2013): http://www.sciencedirect.com/science/article/pii/S0092867413002857 ($31.50)
- c-fos: http://www.uniprot.org/uniprot/P01100
- CREB2: http://www.genome.jp/dbget-bin/www_bget?hsa:468
- NMDAR1: http://www.kegg.jp/dbget-bin/www_bget?hsa:2902
- You may want to view/download the uniprot datasets here and here.
- Keywords: GSK-3, breast cancer (PKB), Glycine, Wnt signaling pathway
- See also this free PMC article about the GSK-3 kinase here.
Notes
- Désactivation sélective du récepteur NMDAR1 (Ser133?)
- Note: Ser133 ? (NMDAR1): un récepteur critique à la formation de la protéine beta-amyloid (APP) 4 d'après de récentes études à ce sujet. [2]
References
- Macías W, Carlson R, Rajadhyaksha A, Barczak A, and Konradi C. Potassium chloride depolarization mediates CREB phosphorylation in striatal neurons in an NMDA receptor-dependent manner. Brain Res. 2001 Feb 2;890(2):222-32. DOI:10.1016/s0006-8993(00)03163-2 |
- De Cesare D, Jacquot S, Hanauer A, and Sassone-Corsi P. Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12202-7. DOI:10.1073/pnas.95.21.12202 |
- Du K and Montminy M. CREB is a regulatory target for the protein kinase Akt/PKB. J Biol Chem. 1998 Dec 4;273(49):32377-9. DOI:10.1074/jbc.273.49.32377 |
- Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, and McKnight GS. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol Cell Biol. 1994 Sep;14(9):6107-16. DOI:10.1128/mcb.14.9.6107-6116.1994 |
- Lee HJ, Mignacca RC, and Sakamoto KM. Transcriptional activation of egr-1 by granulocyte-macrophage colony-stimulating factor but not interleukin 3 requires phosphorylation of cAMP response element-binding protein (CREB) on serine 133. J Biol Chem. 1995 Jul 7;270(27):15979-83. DOI:10.1074/jbc.270.27.15979 |
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