User:Tkadm30/Notebook/Acetonitrile

Overview

Acetonitrile is a common biosolvent for many chemical reactions including alkylation of tertiary amines, organic synthesis of oligonucleotides, and is used primarly as a important DNA synthesis buffer agent.

Use

• • For (mobile-phase) polypeptide pairing of psychotropic alkylamines, see http://www.ebi.ac.uk/QuickGO/GTerm?id=GO:0008174#term=stats
  • in SPPS (solid-phase peptide synthesis): As a mRNA ligand buffer agent for organic synthesis of orthogonal peptides/oligonucleotides...

Safety

• See http://en.wikipedia.org/wiki/Acetonitrile#Safety.

See also

• DMF
• THF
• Solid Phase Peptide Synthesis
• Succinic acid
• Tributylamine

References

• [Complete/extend this section!]