User:Daniela A. Garcia S./Notebook/SSynBio/2012/05/02

Synthetic Biology: Mapping the Scientific Landscape

Potential implications of synthetic biology for the three objectives of the convention: the conservation of biodiversity; the sustainable use of biodiversity, and; the fair and equitable sharing of benefits arising from the utilization of genetic resources.

A little of history

1980 and 1990, references to synthetic biology appeared sporadically in the literature. Recognition of the historical legacy of Leduc's (1912) La Biologie Synthétique. 2000, Rawls-Eric Kool, debut of synthetic biology. It was only in 2007 taht ht enumber of publications exceeded 100 records.

Clases of synthetic Biology

Benner-Sismour

1. Understangind natural biology, focus on assembling non-natural or synthetic components to create chemical systems that support Darwinian or biological evolution.
2. Engineering view, focus on extracting interchangeable parts from living systems to create construction units anddevices that may or may not be analogous with existing biological systems.

Both classes focus on the chemical synthesis of biological components ranging from gene circuits to entire genomes.

Endy

1. Biologists. Synbio as a means to understand natural biological systems.
2. Chemists.It is an extension of synthetic chemistry leading to the development of novel molecules and advancing research on the origin of life.
3. Re-writers. Synbio offers the promise to optimising biological systems including refactoring existing genomes.
4. Engineers. Technology that requieres the development of foundational technologies that make the design and construction of engineered biological systems easier.

Lorenyo-Danchin

Any biological system can be regarded as a combination of individual functional elements. The limited number of elements can be combined in novel configuratios to modify existing properties or to create new ones.

Language of SynBio

Synthetic biology is being constructed from a combination of convergences and overlaps with other areas of science and technology. It is being constructed from a core of work around genetic circuits and networks

To know

Cartagena Protocol on Biosafety

Ref: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0034368

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