User:Cristina Malagelada Grau

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Contact Info

Cristina Malagelada Grau

• Cristina Malagelada Grau, PhD. Ramón y Cajal investigator.
• Contact information: Department of Pharmacology, University of Barcelona
• Address: Casanova 143 main floor Barcelona 08036, Catalonia, Spain
• Phone: +34-934024526
• E-mail: cristina.malagelada@ub.edu

Education

• 2010-2015, Ramon y Cajal investigator, Universitat de Barcelona , Barcelona , Catalonia, (Spain)
• 2008-2010,Associate research scientist, Columbia University New York (NY) (USA)
• 2004-2008, Postdoctoral research scientist, Columbia University New York (NY) (USA)
• 2003-2004, Postdoctoral fellowship, Mount Sinai School of Medicine, New York (NY) (USA)
• 2003, PhD,Biochemistry, Universitat Autònoma de Barcelona, Catalonia (Spain)
• 2000, MS, Neurochemistry, Universitat Autònoma de Barcelona, Catalonia (Spain)
• 1998, BS, Biochemistry, Universitat Autònoma de Barcelona, Catalonia (Spain)

Research interests

1. Parkinson's disease
2. Neurodegeneration
3. Neurogenesis

Publications

1. Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, and Greene LA. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. J Neurosci. 2010 Jan 20;30(3):1166-75. DOI:10.1523/JNEUROSCI.3944-09.2010 |
2. Timmins JM, Ozcan L, Seimon TA, Li G, Malagelada C, Backs J, Backs T, Bassel-Duby R, Olson EN, Anderson ME, and Tabas I. Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest. 2009 Oct;119(10):2925-41. DOI:10.1172/JCI38857 |
3. Badiola N, Malagelada C, Llecha N, Hidalgo J, Comella JX, Sabriá J, and Rodríguez-Alvarez J. Activation of caspase-8 by tumour necrosis factor receptor 1 is necessary for caspase-3 activation and apoptosis in oxygen-glucose deprived cultured cortical cells. Neurobiol Dis. 2009 Sep;35(3):438-47. DOI:10.1016/j.nbd.2009.06.005 |
4. Levy OA, Malagelada C, and Greene LA. Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps. Apoptosis. 2009 Apr;14(4):478-500. DOI:10.1007/s10495-008-0309-3 |
5. Malagelada C, Jin ZH, and Greene LA. RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. J Neurosci. 2008 Dec 31;28(53):14363-71. DOI:10.1523/JNEUROSCI.3928-08.2008 |
6. Malagelada C, Jin ZH, and Greene LA. RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. J Neurosci. 2008 Dec 31;28(53):14363-71. DOI:10.1523/JNEUROSCI.3928-08.2008 |
7. Malagelada C, Jin ZH, and Greene LA. RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation. J Neurosci. 2008 Dec 31;28(53):14363-71. DOI:10.1523/JNEUROSCI.3928-08.2008 |
8. Xifró X, Falluel-Morel A, Miñano A, Aubert N, Fadó R, Malagelada C, Vaudry D, Vaudry H, Gonzalez B, and Rodríguez-Alvarez J. N-methyl-D-aspartate blocks activation of JNK and mitochondrial apoptotic pathway induced by potassium deprivation in cerebellar granule cells. J Biol Chem. 2006 Mar 10;281(10):6801-12. DOI:10.1074/jbc.M504571200 |
9. Biswas SC, Ryu E, Park C, Malagelada C, and Greene LA. Puma and p53 play required roles in death evoked in a cellular model of Parkinson disease. Neurochem Res. 2005 Jun-Jul;30(6-7):839-45. DOI:10.1007/s11064-005-6877-5 |
10. Malagelada C, Xifró X, Miñano A, Sabriá J, and Rodríguez-Alvarez J. Contribution of caspase-mediated apoptosis to the cell death caused by oxygen-glucose deprivation in cortical cell cultures. Neurobiol Dis. 2005 Oct;20(1):27-37. DOI:10.1016/j.nbd.2005.01.028 |
11. Xifro X, Malagelada C, Miñano A, and Rodríguez-Alvarez J. Brief exposure to NMDA produces long-term protection of cerebellar granule cells from apoptosis. Eur J Neurosci. 2005 Feb;21(4):827-40. DOI:10.1111/j.1460-9568.2005.03935.x |
12. Malagelada C, Xifró X, Badiola N, Sabrià J, and Rodríguez-Alvarez J. Histamine H2-receptor antagonist ranitidine protects against neural death induced by oxygen-glucose deprivation. Stroke. 2004 Oct;35(10):2396-401. DOI:10.1161/01.STR.0000141160.66818.24 |

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13. ISBN:0879697164

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