User:ClarkeS

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saclarke at MIT
saclarke at MIT
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I am an incoming BE graduate student working in the [[Endy Lab]] this summer.
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I am a first-year [http://web.mit.edu/be/ Biological Engineering] (BE, course 20) graduate student who worked in the [[Endy Lab]] this past summer 2005. This semester I am taking classes, and looking for a lab I would like to join.  The Endy lab is one possibility.  I naively expected to be able to continue some lab work, but classes and other demands of the first year have made that practically impossible.
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*B.S.M.E., [http://www.utexas.edu University of Texas at Austin], biomedical technical area
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*B.A., [http://www.utexas.edu University of Texas at Austin], Plan II Liberal Arts Honors Program
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*Fulbright grant, Milan, Italy, independent study of industrial and engineering design methods, and classes in biomaterials at the [http://www.polimi.it Politecnico di Milano]
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My background is in mechanical engineering and design, but not of things quite as small as [[BioBricks]].
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==Potential research topics==
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*Scaling of engineered biology
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*Replicating biological machines
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*Technologies/vocabularies to make biological engineering easier
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*Biomimicry, bioscaffolds for material processing
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*Recycling/"cradle to cradle" design of biological systems
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*Usability of biological design software or methods
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==Classes==
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*BE.420
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*BE.430
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*[http://web.mit.edu/biophysics/sbio/ 7.81 Systems Biology]
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*[http://math.mit.edu/18085 18.085 Applied Math for Engineers]
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My background is in mechanical engineering and design, but not of things quite as small as BioBricks.  Please forgive the questions about methods that might seem routine.  I'm still trying to suss out the techniques for the line between the mundane and the not yet possible.
 
==Projects==
==Projects==
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*My first project is [[Orthogonal cloning of clpXP]] system from ''E. coli'' into yeast.
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*My first project was the [[Orthogonal cloning of clpXP]] from ''E. coli'' into yeast. So far I've been more successful at learning molecular biology and techniques by making mistakes than at cloning into yeast.  My work is documented in a lab notebook, but I would like to move to a wiki or other on-line lab notebook for searching, organization, and linking.  
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*Another possible project is the construction of a low copy number plasmid for use with BioBricks.  It might be  based on the F or mini-F plasmid from ''E. coli''.
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*Another useful project would be the construction of a low copy number plasmid for use with BioBricks.  It might be  based on the F or mini-F plasmid from ''E. coli''.

Revision as of 12:39, 9 October 2005

Contents

Bio

Sean Clarke

saclarke at MIT

I am a first-year Biological Engineering (BE, course 20) graduate student who worked in the Endy Lab this past summer 2005. This semester I am taking classes, and looking for a lab I would like to join. The Endy lab is one possibility. I naively expected to be able to continue some lab work, but classes and other demands of the first year have made that practically impossible.

My background is in mechanical engineering and design, but not of things quite as small as BioBricks.

Potential research topics

  • Scaling of engineered biology
  • Replicating biological machines
  • Technologies/vocabularies to make biological engineering easier
  • Biomimicry, bioscaffolds for material processing
  • Recycling/"cradle to cradle" design of biological systems
  • Usability of biological design software or methods

Classes


Projects

  • My first project was the Orthogonal cloning of clpXP from E. coli into yeast. So far I've been more successful at learning molecular biology and techniques by making mistakes than at cloning into yeast. My work is documented in a lab notebook, but I would like to move to a wiki or other on-line lab notebook for searching, organization, and linking.
  • Another useful project would be the construction of a low copy number plasmid for use with BioBricks. It might be based on the F or mini-F plasmid from E. coli.
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