User:ClarkeS

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[[BE_Board:Sean_Clarke | directory info]]  
[[BE_Board:Sean_Clarke | directory info]]  
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I am a first-year [http://web.mit.edu/be/ Biological Engineering] (BE, MIT Course XX) graduate student.  I have passed my qualifying exam and joined the Alm lab.  I worked in the [[Endy Lab]] in the summer of 2005.  This summer I am formulating a thesis project directed at engineering stress tolerance.   
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I am a second-year [http://web.mit.edu/be/ Biological Engineering] (BE, MIT Course XX) graduate student in the Alm lab (48-324)Our focus is on the evolution of microbial genomes, and I am specifically working on engineering genetic diversity and stress tolerance in ''Vibrio splendidus''I hope to determine what alleles and loci contribute to environmental stress tolerance and whether these have analogues in the ocean environment.
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I'm the first-year class representative to the [[BE Board | BE graduate student board]], so I am open to suggestions about improving the first-year experience.
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Along with [[Amy Nichols]], I am a coordinator of the [[BE Board | BE graduate student board]]I was the first-year class representative last year, and am always happy to hear suggestions about improvements to the department.
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==Past life and credentials==
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My background is in mechanical engineering and design, but not of things quite as small as [[BioBricks]].
*B.S.M.E., [http://www.utexas.edu University of Texas at Austin], biomedical technical area
*B.S.M.E., [http://www.utexas.edu University of Texas at Austin], biomedical technical area
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*B.A., [http://www.utexas.edu University of Texas at Austin], Plan II Liberal Arts Honors Program
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*B.A., [http://www.utexas.edu University of Texas at Austin], [http://www.utexas.edu/cola/progs/plan2/ Plan II] Liberal Arts Honors Program
*Fulbright grant, Milan, Italy, independent study of industrial and engineering design methods, and classes in biomaterials at the [http://www.polimi.it Politecnico di Milano]
*Fulbright grant, Milan, Italy, independent study of industrial and engineering design methods, and classes in biomaterials at the [http://www.polimi.it Politecnico di Milano]
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My background is in mechanical engineering and design, but not of things quite as small as [[BioBricks]].
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I've also lived in Long Island, St. Louis, and Washington, DC, all of which I will defend and criticize passionately.
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==Potential research topics==
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==Other research interests==
*Engineering microbial stress tolerance
*Engineering microbial stress tolerance
*Relating stress tolerance to genome loci
*Relating stress tolerance to genome loci
*Resequencing evolved microbes
*Resequencing evolved microbes
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*Scaling of engineered biology
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*Scaling of engineered biology to industrial purposes
*Design and use of replicating biological machines
*Design and use of replicating biological machines
*Technologies/vocabularies to make biological engineering easier
*Technologies/vocabularies to make biological engineering easier
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*Ethics and philosophy of science instruction for scientists/engineers
*Biomimicry, bioscaffolds for material processing
*Biomimicry, bioscaffolds for material processing
*Recycling/"cradle to cradle" design of biological systems
*Recycling/"cradle to cradle" design of biological systems
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*BE.420
*BE.420
*BE.430
*BE.430
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*[http://web.mit.edu/biophysics/sbio/ 7.81 Systems Biology]
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*[http://web.mit.edu/biophysics/sbio/ 7.81 Systems Biology] Excellent class, Alex van Oudenaarden
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*[http://math.mit.edu/18085 18.085 Applied Math for Engineers]
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*[http://math.mit.edu/18085 18.085 Applied Math for Engineers] with Gil Strang, who might have taught your parents, and is indefatigable, still revising his book daily.
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*[http://web.mit.edu/7.56 7.56 Graduate Cell Biology]
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*[http://web.mit.edu/7.56 7.56 Graduate Cell Biology], with an emphasis on yeast, since that's what Stephen Bell and Frank Solomon work on.
==Past Projects==
==Past Projects==
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*My first project at MIT was the [[Orthogonal cloning of clpXP]] from ''E. coli'' into yeast. So far I've been more successful at learning molecular biology and techniques by making mistakes than at cloning into yeast.  This work is continuing in someone else's more capable hands.
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*My first project at MIT was during the summer of 2005 when I tried the [[Orthogonal cloning of clpXP]] from ''E. coli'' into yeast. I was more successful at learning molecular biology and techniques by making mistakes than at cloning into yeast.  This work is continuing in someone else's more capable hands.

Revision as of 09:56, 25 August 2006

Contents

Bio

Sean Clarke

saclarke at MIT

directory info

I am a second-year Biological Engineering (BE, MIT Course XX) graduate student in the Alm lab (48-324). Our focus is on the evolution of microbial genomes, and I am specifically working on engineering genetic diversity and stress tolerance in Vibrio splendidus. I hope to determine what alleles and loci contribute to environmental stress tolerance and whether these have analogues in the ocean environment.

Along with Amy Nichols, I am a coordinator of the BE graduate student board. I was the first-year class representative last year, and am always happy to hear suggestions about improvements to the department.

Past life and credentials

My background is in mechanical engineering and design, but not of things quite as small as BioBricks.

I've also lived in Long Island, St. Louis, and Washington, DC, all of which I will defend and criticize passionately.

Other research interests

  • Engineering microbial stress tolerance
  • Relating stress tolerance to genome loci
  • Resequencing evolved microbes
  • Scaling of engineered biology to industrial purposes
  • Design and use of replicating biological machines
  • Technologies/vocabularies to make biological engineering easier
  • Ethics and philosophy of science instruction for scientists/engineers
  • Biomimicry, bioscaffolds for material processing
  • Recycling/"cradle to cradle" design of biological systems
  • Usability of biological design software and equipment
  • Biomineralization

Classes

Past Projects

  • My first project at MIT was during the summer of 2005 when I tried the Orthogonal cloning of clpXP from E. coli into yeast. I was more successful at learning molecular biology and techniques by making mistakes than at cloning into yeast. This work is continuing in someone else's more capable hands.
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