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==  Homework Questions and Answers ==
==  Homework Questions and Answers ==
=== Week 2: DNA Replication ===
#In Lopes, et al, why does ablation of TLS activity in rad14 mutants increase the number of internal ssDNA gaps and shorten the distance of internal gaps from the elongation point?
#Considering what we know from Heller, et al, how could the in vivo conditions in Lopes, et al be altered to predictably shorten the average observed internal ssDNA gap?

Revision as of 00:12, 11 April 2007

Undergraduate

Graduated in 2003 with a B.S. from Montana State University-Bozeman, Department of Chemistry and Biochemistry



Graduate Education

Currently pursuing a Ph.D. at Oregon Health and Science University, Department of Biochemistry and Molecular Biology.

Research Advisor: Dr. J. Eric Gouaux

Thesis Topic: Structural characterization of membrane transport mechanisms by x-ray crystallography



Publications

  1. Piscitelli CL, Angel TE, Bailey BW, Hargrave P, Dratz EA, and Lawrence CM. Equilibrium between metarhodopsin-I and metarhodopsin-II is dependent on the conformation of the third cytoplasmic loop. J Biol Chem. 2006 Mar 10;281(10):6813-25. DOI:10.1074/jbc.M510175200 | PubMed ID:16407202 | HubMed [1]
  2. Wilkinson RA, Piscitelli C, Teintze M, Cavacini LA, Posner MR, and Lawrence CM. Structure of the Fab fragment of F105, a broadly reactive anti-human immunodeficiency virus (HIV) antibody that recognizes the CD4 binding site of HIV type 1 gp120. J Virol. 2005 Oct;79(20):13060-9. DOI:10.1128/JVI.79.20.13060-13069.2005 | PubMed ID:16189008 | HubMed [2]

All Medline abstracts: PubMed | HubMed



Contact Info

E-Mail piscitel AT ohsu DOT edu


Homework Questions and Answers

Week 2: DNA Replication

  1. In Lopes, et al, why does ablation of TLS activity in rad14 mutants increase the number of internal ssDNA gaps and shorten the distance of internal gaps from the elongation point?
  2. Considering what we know from Heller, et al, how could the in vivo conditions in Lopes, et al be altered to predictably shorten the average observed internal ssDNA gap?