User:Ana-Teresa Maia

Contact Info

Ana-Teresa Maia (an artistic interpretation)

• Ana-Teresa Maia

Group Leader of Cancer Functional Genomics Group
Assistant Professor
IBB/CBME Laboratório Associado
Department of Biomedical Sciences and Medicine
University of Algarve
Gambelas, Faro, Portugal
Email me through OpenWetWare

Education

• 2003, PhD, Institute of Cancer Research, London, U.K.
• 1999, MS, Imperial College of Science, Technology and Medicine, London, U.K.
• 1997, BS, Faculty of Science and Technology, New University of Lisbon, Monte da Caparica, Portugal

Research Interests

I am interested in studying allelic imbalance in gene expression, a common feature of our genome. Due to regulatory polymorphisms, which can occur both in cis- and in trans-, a large number of our genes are preferentially expressed from one allele. This unequal expression can contribute to susceptibility to common diseases. My main aim is to try to use this concept to develop a new method to study predisposition to breast cancer. Additionally, I am investigating the role that this imbalance can play in tumour biology, namely in the effect of mutations and treatment response.

Publications

For all publications http://publicationslist.org/ana-teresa.maia

Selected Papers

1. Curtis CN et al. (2012) Nature:486(7403):346-52 pmid= 22522925

2. Maia AT et al. (2012) Breast Cancer Research:R63pmid= 22513257

3. Maia AT et al. (2009) Breast Cancer Research:R88 pmid= 20003265

4. Meyer KM, Maia AT et al. (2008) PLoS Biology:6(5):e108 pmid= 18462018

5. Udler M, Maia AT et al. (2007) Journal of Clinical Oncology:25(21):3015-23 pmid= 17634480

Lab Members

• Joana Xavier, Post-doctoral Fellow
• Cátia Rocha, MSc Student

Former Lab Members

• Joana Lopes, MSc Student
• Inês Gomes, Undergraduate Student

Funding

• 2013 - 2015 “Cis-regulation of somatic mutations in breast and ovarian cancers”; PTDC/BIM-ONC/1338/2012; Foundation for Science and Technology, Portugal
• 2012 - 2016 Marie Curie Integration Grant, GenCar - Genetic Control of Gene Expression in Cancer Risk, FP7-MC-CIG, European Union
• 2009 – 2010 Breast Cancer Research Foundation Grant, U.S.A., Differential Allelic Expression Analysis of Susceptibility Loci in Breast Cancer, USA
• 2008 – 2009 Breast Cancer Research Foundation Grant, U.S.A., Differential Allelic Expression Analysis of Susceptibility Loci in Breast Cancer, USA

Teaching

Integrated Masters in Medicine

         * PBL classes to 1st and 2nd years
         * Seminars in Basic Sciences
         * Coordinator of Student Chosen Module for 2 year (5 week training in laboratory or clinical work))

Masters of Science in Oncobiology - Molecular Mechanisms of Cancer

         Vice-Director
         * Oncogenetics and Oncogenomics
         * Genetic Toxicology
         * Clinical Oncology

Masters of Science in BIomedical Sciences

         * Computational Biology

Undergraduate Degree in BIomedical Sciences

         * Human Genetics

Useful links

• CBME http://www.cbme.ualg.pt/
  
• DCBM/UAlg http://dcbm.ualg.pt/home/
  
• MSc in Oncobiology http://dcbm.ualg.pt/home/pt/curso/1716