User:Alexis Courbet
Research interests
- Biocomputing
- Cellular/molecular engineering
- Biosensing systems
- Synthetic gene circuits
- Synthetic biochemical circuits
- CAD for synthetic biology
- Protocells & minimal systems
- Microfluidics
- Translational medicine and diagnosis
- Multidisciplinary science
During my PhD, I applied synthetic biology to human health and biotechnology.
I developped concepts, systematic methods, computational tools and biological standards to: 1. Engineer next-generation diagnostics. I engineered autonomous and programmable biosensors integrating multiplexed pathological biomarker detection and complex biological signal processing to develop intelligent diagnostic devices.
2. Engineer novel biocomputing devices that solve complex problems and process/interface biological information at the microscale. I developed microfluidic and computer assisted methodologies to program these synthetic biosystems from the bottum-up.
I believe that collaboration between scientists and promotion of interdisciplinarity is the key to understand and engineer biology.
Contact Info
- Alexis Courbet
- Sys2diag laboratory, CNRS
Complex biological systems modelling and engineering for diagnosis
- Montpellier, France
- Email me through OpenWetWare
Education
- 2012-2015, PhD at The National Center for Scientific Research (CNRS)&Bio-Rad/Stanford University
- 2012, MS in Molecular and Cellular Biophysics, University of Montpellier
- 2011-2015, Residency in Clinical Toxicology, Pharmaceutical innovation and Research
- 2011, MS in Cellular and Molecular Biology, University Paris Sud 11
- 2010, BS, University of Paris Sud 11
- 2010, BMSc, University of Paris Sud 11
Publications
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates
Science Translational Medicine, 2015 May 27;7(289):289ra83
Alexis Courbet, Drew Endy, Eric Renard, Franck Molina, and Jérôme Bonnet
Abstract PDF
Supplementary Materials
Computing with Synthetic Protocells
Acta Biotheor., 2015 May 13;
Alexis Courbet, Patrick Amar, and Franck Molina
Abstract PDF
Engineering next generation diagnostics through synthetic biology
University of Montpellier, Medical Thesis, 2015 July 2;
Alexis Courbet
PDF
