University of California Berkeley/Lawrence Berkeley National Laboratory
DOE Joint BioEnergy Institute
Building 978, 1 Cyclotron Road
Berkeley, CA 94720 USA
Office Tel: 510-495-2462
Office Fax: 510-486-4252
A molecular biologist and biochemist with ten years experience in the field of cell wall (extracellular matrix). I am interested in understanding genes and enzymes involved in the synthesis and remodeling of extracellular matrix components.
Education and experience
- Doctor of biology (Ph.D.), Bioprocess Engineering, 2005 - 2008
The United Graduate School of Agricultural Sciences (UGAS), Iwate University, Japan
- Master of Science (MS), Bioscience and Technology, 2003 - 2005
Graduate School of Agricultural Sciences, Iwate University, Japan
- Bachelor of Science (BS), Bioscience and Technology, 1999 – 2003
Faculty of Agriculture, Iwate University, Japan
- Biologist Post-doctoral Research Fellow 2008 - Present
at Lawrence Berkeley National Laboratory. Adviser: Dr.Henrik Scheller. My molecular biology, biochemistry and bioinformatics analysis have revealed functions of several Golgi-localized carbohydrate active enzymes, which are important for understanding mechanism of cell wall components, deposition, and accumulation. This study was funded by the US Department of Energy, Office of Science, Office of Biological and Environmental Research.
- 21st Century Center of Excellence (COE) Program Graduate Research Assistant 2004 - 2008
At the United Graduate School of Agricultural Sciences (UGAS), Iwate University. Adviser: Dr. Shin-ichiro Kidou. My subcellular localization analysis and protein-protein interaction analysis have revealed that a novel grass protein is localized on Golgi apparatus membrane and is involved in synthesis of grass unique cell wall polysaccharide. This study was funded by funded by the 21st Century Center of Excellence Program - Establishment of Thermobiosystem Research Program from the Japan Society for the Promotion of Science (JSPS).
- Graduate Research Associate 2003 - 2008
At Cryobiofrontier Research Center (CRC), Iwate University. Adviser: Dr. Shin-ichiro Kidou. I developed new molecular biology technique, namely “Virus-Induced Gene Silencing (VIGS)” applied to cell-wall-related genes in cereal crops. This study was funded by a grant-in-aid from Iwate University, Japan.
- Visiting Research Scholar 2007
At Department Molecular, Cellular & Developmental Biology, Yale University. Adviser: Dr. Timothy Nelson. I performed a study entitled -“Unraveling the gene network involved in the barley seed development by LCM (Laser-captured Microdissection)") with Professor Timothy Nelson at department of Molecular, Cellular and Developmental Biology of Yale University This study was funded by a Young Overseas Joint Research Fellowship granted by the Japanese Society of Plant Physiologists (JSPP).
- Undergraduate Research Assistant 2001 - 2003
At Faculty of Agriculture, Iwate University. Advisers: Dr. Masao Miyazaki and Dr.Hideharu Taira, I performed expression analysis and esterase and peptidase activity assay of a major urinary protein of the domestic cat which regulates the production of Felinine, a putative pheromone precursor. This study was funded by a grant-in-aid from Iwate University, Japan.
- Ai Oikawa, Christian Have Lund, Yumiko Sakuragi, Henrik Vibe Scheller. Golgi-localized enzyme complexes for plant cell wall biosynthesis. Trend in Plant Science, 18:49-58 Article
- Xuewei Chen, Miguel E Vega-Sánchez, Yves Verhertbruggen, Dawn Chiniquy, Patrick E Canlas, Alexandra Fagerström, Lina Prak, Ulla Christensen, Ai Oikawa, Mawsheng Chern, Shimin Zuo, Lin Fan, Manfred Auer, William GT Willats, Laura Bartley, Jesper Harholt, Henrik V Scheller, Pamela C Ronald. Inactivation of OsIRX10 leads to decreased xylan content in ricestem cell walls and improved biomass saccharification. Molecular Plant, 6:570-573 Article
- April J. M. Liwanag, Berit Ebert, Yves Verhertbruggen, Emilie A. Rennie, Carsten Rautengarten, Ai Oikawa, Mathias C. F. Andersen, Mads H. Clausen, and Henrik Vibe Scheller. Pectin Biosynthesis: GALS1 in Arabidopsis thaliana Is a β-1,4-Galactan β-1,4-Galactosyltransferase. Plant Cell, 24:5024-5036 Article
- Sara Fasmer Hansen, Jesper Harholt, Ai Oikawa, Henrik Vibe Scheller. Plant glycosyltransferases beyond CAZy: a perspective on DUF families. Frontier in plant science, 3:59 Article
- Yves Verhertbruggen, Lan Yin, Ai Oikawa, Henrik Vibe Scheller. Mannan synthase activity in the CSLD family. Plant Signaling & Behavior, 6:1620-1623 PDF
- Lan Yin, Yves Verhertbruggen, Ai Oikawa, Chithra Manisseri, Bernhard Knierim, Lina Prak, Jacob Krüger Jensena, J. Paul Knox, Manfred Auer, William G. T. Willats, Henrik Vibe Scheller. The Cooperative Activities of CSLD2, CSLD3 and CSLD5 are Required for Normal Arabidopsis Development. Molecular Plant, 4:1024-1037 PDF
- Ai Oikawa, Hiren J. Joshi, Emilie A. Rennie, Berit Ebert, Chithra Manisseri, Joshua L. Heazlewood and Henrik Vibe Scheller. An integrative approach to the identification of Arabidopsis and rice genes involved in xylan and secondary wall development. PLoS One, 5:e15481 Article
- Ai Oikawa, Kazuya Nagai, Kiyoaki Kato, Shin-ichiro Kidou. Gene silencing of barley P23k involved in secondary wall formation causes abnormal tiller formation and intercalary elongation. Breeding Science, 59: 664-670 PDF
- Ai Oikawa, Abidur Rahman, Tetsuro Yamashita, Hideharu Taira and Shin-ichiro Kidou. Virus-induced gene silencing of P23k in barley leaf reveals morphological changes involved in secondary wall formation. Journal of Experimental Botany, 58:2617-2625 PDF
- Ai Oikawa, Tetsuro Yamashita, Hideharu Taira, Shin-ichiro Ejiri and Shin-ichiro Kidou. Jasmonate-induced 23kD protein (JIP-23) is involved in seed development of barley. Plant Biotechnology, 24:217-220 PDF
- Shin-ichiro Kidou, Ai Oikawa, Naoko Sasaki, Hiroshi Yasuda, Tetsuro Yamashita, Hiroyuki Koiwa, Kiyoaki Kato, Shin-ichiro Ejiri. Identification of a 23 KD protein (P23k) related to the sugar supply in germinating seed. Plant Biotechnology, 23:357-364 PDF
Awards and Grants received
- National Interest Waver (NIW) for Permanent Residency 2013
As an alien who has exceptional ability and whose employment in the United States would greatly benefit the national, the NIW was granted by U.S. Citizenship and Immigration Service (USCIS).
- The Yamada Science Foundation (YSF) Abroad Research Grant 2008
The YSF was established to promote basic natural science by providing funding complementary to that of the Japanese government. The YSF extends financial support to five Japanese researchers (selected amongst a pool of applicants) for abroad research projects. I was awarded the 2008 abroad research grant in order to conduct a study on “Unraveling the gene network involved in the construction of plant cell wall” with Dr. Henrik Vibe Scheller at DOE Joint BioEnergy Institute (CA, USA).
- The Japanese Society of Plant Physiologists (JSPP) Fellow 2008
The JSPP is one of the largest societies in Japan. I was awarded, by the Japanese Society of Plant Physiologists (JSPP), the Young Overseas Joint Research Fellowship for conducting a collaborative research (the subject of which was “Unraveling the gene network involved in the barley seed development by LCM (Laser-captured Microdissection)") with Professor Timothy Nelson at department of Molecular, Cellular and Developmental Biology of Yale University.
- Japan Student Services Organization (JASSO) - Scholarship Programs for Japanese Students 2008
I was granted a scholarship by JASSO in consideration of my outstanding achievements and of the results I obtained during the course of my Ph.D. studies.
- The Life Science Foundation Travel Grant 2007
I was awarded a Life Science Travel Grant in order to cover the costs of (i) travelling abroad in order to conduct a collaborative research with Professor Timothy Nelson at Yale University, and (ii) attending the Annual meeting of American Society of Plant Biologists (ASPB) held in Chicago, USA.