User:Ahmad A. Mannan

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BIOMATHS JOURNAL CLUB

We put together a journal club for sharing and discussing papers and problems (theory) of mathematical modelling of biological systems (both stochastically and deterministically).

NEXT GATHERING

Example of an image I uploaded and embedded into my Wiki.
  • Date: THURSDAY 11TH FEBRUARY
  • Time: 3-4PM
  • Venue: HUXLEY 747


COMPILATION OF PAPERS TO READ

  • Division in Escherichia coli is triggered by a size-sensing rather than a timing mechanism[1]
  • Slow Protein Fluctuations Explain the Emergence of Growth Phenotypes and Persistence in Clonal Bacterial Populations [2]
  • Stress‐response balance drives the evolution of a network module and its host genome [3]
  • Emergent genetic oscillations in a synthetic microbial consortium [4]
  • Evolutionary consequences of drug resistance: shared principles across diverse targets and organisms [5]
  • A noisy linear map underlies oscillations in cell size and gene expression in bacteria [6]
  • Replication of DNA in bacteria with heterogeneous generation times [7]
  • Duplication of the bacterial cell and its initiation [8]
  • Dilution of the cell cycle inhibitor Whi5 controls budding-yeast cell size [9]
  • A growth‐rate composition formula for the growth of E. coli on co‐utilized carbon substrates [10]
  • Macromolecular Crowding as a Regulator of Gene Transcription [11]
  • Cell Size and the Initiation of DNA Replication in Bacteria [12]
  • How fast-growing bacteria robustly tune their ribosome concentration to approximate growth-rate maximisation [13]
  • Optimization of lag time underlies antibiotic tolerance in evolved bacterial populations [14]
  • Does evolutionary theory need a rethink? [15]
  • A cross-chiral RNA polymerase ribozyme [16]
  • Cell cycle: It takes three to find the exit [17]
  • Loss of growth homeostasis by genetic decoupling of cell division from biomass growth: implication for size control mechanisms [18]
  • Causal signals between codon bias, mRNA structure, and the efficiency of translation and elongation [19]
  • Cell dynamics and gene expression control in tissue homeostasis and development [20]
  • Quantitative evolutionary dynamics using high-resolution lineage tracking [21]

with comment HERE

  • Conditional density-based analysis of T cell signaling in single-cell data [22]
  • Evolution of context dependent regulation by expansion of feast/famine regulatory proteins [23]
  • Carbon source-dependent expansion of the genetic code in bacteria [24]
  • Reducing the genetic code induces massive rearrangement of the proteome [25]
  • Conserved codon composition of ribosomal protein coding genes inEscherichia coli, Mycobacterium tuberculosis and Saccharomyces cerevisiae: lessons from supervised machine learning in functional genomics [26]

CONTACT INFORMATION

Please feel free to e-mail me if you would like to suggest another paper to discuss at the group:


Publications

  1. Soma Y, Tsuruno K, Wada M, Yokota A, and Hanai T. Metabolic flux redirection from a central metabolic pathway toward a synthetic pathway using a metabolic toggle switch. Metab Eng. 2014 May;23:175-84. DOI:10.1016/j.ymben.2014.02.008 | PubMed ID:24576819 | HubMed [Soma2014]

    Really interesting paper!

  2. ISBN:9783527318742 [Klipp2009]

Useful Links

  • Introductory tutorial
  • OpenWetWare help pages
  • Link to the tutorial on adjusting images in Wikis.
  • Link to download the Wiki construction 'Cheat-Sheet' from my Dropbox. It details the simple commands needed to construct your Wiki pages.
  • Further advanced level of editing Cheat-Sheets can be found HERE.
  • Beware of copyright issues and fact that figures uploaded will fall under the Creative Commons license. Please see the following link.