User:Adam B. Fisher

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Adam B. Fisher<br>
Adam B. Fisher<br>
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[[Image:Afishinlab.jpg|thumb|225px|left|Candidly counting some colonies]]
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[[Image:Afishinlab.jpg|thumb|225px|left|Candidly counting colonies]]
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'''''In nature hybrid species are usually sterile, but in science the reverse is often true.''''' <br />
'''''In nature hybrid species are usually sterile, but in science the reverse is often true.''''' <br />
'''''Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.''''' <br />
'''''Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.''''' <br />
- Francis Crick <br />
- Francis Crick <br />
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As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, chemical biology and quantitative biology to facilitate microbial engineering. As an undergraduate at Virginia Tech concentrating in Microbiology and Immunology, I had my first exposure to these emergent fields while working in the laboratory of [[Jean_Peccoud|Dr. Jean Peccoud]]. Alongside [[Matthew_W_Lux|Matthew Lux]] I strove to build out and characterize a bi-stable genetic toggle switch. Subsequently, I've joined the lab of [[Fong|Dr. Stephen Fong]] at Virginia Commonwealth University endeavoring toward a PhD in Integrative Life Sciences. Currently, I am involved in projects revolving around ''ex vivo'' approaches for cloning and synthetic biology, a synthetic biomolecular delivery system and a cost analysis for the interpretation of genome-scale models. My overall research interests include:
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As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, chemical biology and quantitative biology to facilitate microbial engineering. At Virginia Tech, I had my first exposure to these emergent fields while working as an undergraduate to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the lab of [[Fong|Dr. Stephen Fong]] at Virginia Commonwealth University endeavoring toward a PhD in Integrative Life Sciences. Currently, I am involved in projects involving ''ex vivo'' approaches for cloning and synthetic biology, a synthetic biomolecular delivery system and a cost analysis for the interpretation of genome-scale models. My research interests include:
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*Cell Free Systems
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*Cell-Free and ''ex vivo'' approaches to molecular biology and biotechnology
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*Synthetic gene assembly
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*Genome engineering and high-throughput cloning
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*Global physiology and single-cell characterization
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*Development of engineering platforms for exotic microorganisms
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*Engineered microbial consortia and microbiota
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*Synthetic metagenomics
*Protein engineering
*Protein engineering
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*Synthetic metagenomics
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*Construction and simulation of genome-scale models
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*Genome-scale metabolic models
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*Statistical modeling of biological sequences
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*Statistical models of biological sequences
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*Engineered microbial consortia
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==Education & Training==
==Education & Training==
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==Publications==
==Publications==
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*Vanee N, '''Fisher A''', Fong S. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64.  
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*'''Fisher, AB''' and Fong, SS. "Lignin biodegradation and industrial implications". AIMS Bioengineering (2014). 1(2): 92-112. doi:10.3934/bioeng.2014.2.92 [http://www.aimspress.com/aimsboa/ch/reader/view_abstract.aspx?file_no=Bioeng09&flag=1]<br/>
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*'''Fisher, AB''', Canfield, ZB, Hayward, LC, Fong, SS & McArthur IV, GM. "Ex vivo DNA assembly". Frontiers in Bioengineering and Biotechnology (2013). doi:10.3389/fbioe.2013.00012 [http://journal.frontiersin.org/Journal/10.3389/fbioe.2013.00012/full]<br/>
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*'''Fisher AB''', Vanee N, & Fong SS. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64. doi:10.1007/978-94-007-5055-5_3. [http://link.springer.com/chapter/10.1007/978-94-007-5055-5_3]
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==Presentations==
==Presentations==
*Poster - DNA Assembly for free: using cellular lysates to decrease cloning costs, Synthetic Biology 6.0. Imperial College of London, UK 9-12 July 2013
*Poster - DNA Assembly for free: using cellular lysates to decrease cloning costs, Synthetic Biology 6.0. Imperial College of London, UK 9-12 July 2013
*Talk/Poster - Cyanobacteria: A sustainable manufacturing platform, iGEM Americas Regional Jamboree. Indiana University Purdue University Indianapolis, Indianapolis, IN, 8-10 October 2011
*Talk/Poster - Cyanobacteria: A sustainable manufacturing platform, iGEM Americas Regional Jamboree. Indiana University Purdue University Indianapolis, Indianapolis, IN, 8-10 October 2011
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==Intellectual Property==
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*'''Fisher AB''', Brooks JP, Fong SS (2013) Cellular Strain Design Using Large-Scale Cost Analysis (Virginia Commonwealth University)
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Current revision

[link title

Adam B. Fisher

Candidly counting colonies
Candidly counting colonies

In nature hybrid species are usually sterile, but in science the reverse is often true.
Hybrid subjects are often astonishingly fertile, whereas if a scientific discipline remains too pure it usually wilts.
- Francis Crick


What I cannot create, I cannot understand.
- Richard Feynman



I am very comfortable with the idea that we can override biology with free will.
- Richard Dawkins



As a researcher, I am broadly interested in integrating approaches and technologies found in synthetic and systems biology, metabolic engineering, chemical biology and quantitative biology to facilitate microbial engineering. At Virginia Tech, I had my first exposure to these emergent fields while working as an undergraduate to build out and characterize a bi-stable genetic toggle switch. Subsequently, I joined the lab of Dr. Stephen Fong at Virginia Commonwealth University endeavoring toward a PhD in Integrative Life Sciences. Currently, I am involved in projects involving ex vivo approaches for cloning and synthetic biology, a synthetic biomolecular delivery system and a cost analysis for the interpretation of genome-scale models. My research interests include:

  • Cell-Free and ex vivo approaches to molecular biology and biotechnology
  • Genome engineering and high-throughput cloning
  • Global physiology and single-cell characterization
  • Development of engineering platforms for exotic microorganisms
  • Engineered microbial consortia and microbiota
  • Synthetic metagenomics
  • Protein engineering
  • Construction and simulation of genome-scale models
  • Statistical modeling of biological sequences


Education & Training

Virginia Commonwealth University · Richmond, VA · 2011 — 2014

  • Ph.D. · Integrative Life Sciences
    • Advised by Stephen S. Fong

Virginia Tech · Blacksburg, VA · 2007 — 2011

  • B.S. · Biological Sciences
    • Concentration in Microbiology & Immunology
  • Minor · Business


Publications

  • Fisher, AB and Fong, SS. "Lignin biodegradation and industrial implications". AIMS Bioengineering (2014). 1(2): 92-112. doi:10.3934/bioeng.2014.2.92 [1]
  • Fisher, AB, Canfield, ZB, Hayward, LC, Fong, SS & McArthur IV, GM. "Ex vivo DNA assembly". Frontiers in Bioengineering and Biotechnology (2013). doi:10.3389/fbioe.2013.00012 [2]
  • Fisher AB, Vanee N, & Fong SS. “Evolutionary Engineering for Industrial Microbiology”. Subcellular Biochemistry: Reprogramming Microbial Metabolic Pathways (New York: Springer Verlag, 2012), Vol. 64. doi:10.1007/978-94-007-5055-5_3. [3]


Presentations

  • Poster - DNA Assembly for free: using cellular lysates to decrease cloning costs, Synthetic Biology 6.0. Imperial College of London, UK 9-12 July 2013
  • Talk/Poster - Cyanobacteria: A sustainable manufacturing platform, iGEM Americas Regional Jamboree. Indiana University Purdue University Indianapolis, Indianapolis, IN, 8-10 October 2011


Intellectual Property

  • Fisher AB, Brooks JP, Fong SS (2013) Cellular Strain Design Using Large-Scale Cost Analysis (Virginia Commonwealth University)



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