Todd:Publications

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Facile Synthesis of Vicinal Diamines via Oxidation of N-phenyltetrahydroisoquinolines with DDQ, A.-S. K. Tsang and M. H. Todd, ''Tetrahedron Lett.'' '''2009''', ''50'', 1199-1202. [http://dx.doi.org/10.1016/j.tetlet.2008.12.101 Paper]
Facile Synthesis of Vicinal Diamines via Oxidation of N-phenyltetrahydroisoquinolines with DDQ, A.-S. K. Tsang and M. H. Todd, ''Tetrahedron Lett.'' '''2009''', ''50'', 1199-1202. [http://dx.doi.org/10.1016/j.tetlet.2008.12.101 Paper]
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Synthesis and DNA Binding Ability of Cyclam-amino Acid Conjugates, A. V. Ramana, M. Watkinson and M. H. Todd, ''Bioorg. Med. Chem. Lett.'' '''2008''', ''18'', 3007-3010. [http://dx.doi.org/10.1016/j.bmcl.2007.05.063 Paper]
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Effective Methods for the Biotinylation of Azamacrocycles, S. Krivickas, E. Tamanini, M. H. Todd and M. Watkinson, ''J. Org. Chem.'' '''2007''', ''72'', 8280-8289. [http://dx.doi.org/10.1021/jo071175v Paper]
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Synthesis and DNA Binding Ability of Cyclam-amino Acid Conjugates, A. V. Ramana, M. Watkinson and M. H. Todd, ''Bioorg. Med. Chem. Lett.'' '''2008''', ''18'', 3007-3010. [http://dx.doi.org/ Paper]
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Is Actin the Praziquantel Receptor?, A. R. Troiani, L. Pica-Mattoccia, C. Valle, D. Cioli, G. Mignogna, F. Ronketti and M. H. Todd, ''Int. J. Antimicrob. Ag.'' '''2007''', ''30'', 280-281. [http://dx.doi.org/10.1016/j.ijantimicag.2007.05.004 Paper]
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Effective Methods for the Biotinylation of Azamacrocycles, S. Krivickas, E. Tamanini, M. H. Todd and M. Watkinson, ''J. Org. Chem.'' '''2007''', ''72'', 8280-8289. [http://dx.doi.org/ Paper]
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Praziquantel Analogues. I. Modification of the Aromatic Ring, F. E. Ronketti, A. V. Ramana, X. Chao-Ming, L. Pica-Mattoccia, D. Cioli and M. H. Todd, ''Bioorg. Med. Chem. Lett.'' '''2007''', ''17'', 4154-4157. [http://dx.doi.org/10.1016/j.bmcl.2007.05.063  Paper]
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Is Actin the Praziquantel Receptor?, A. R. Troiani, L. Pica-Mattoccia, C. Valle, D. Cioli, G. Mignogna, F. Ronketti and M. H. Todd, ''Int. J. Antimicrob. Ag.'' '''2007''', ''30'', 280-281. [http://dx.doi.org/ Paper]
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Open Access and Open Source in Chemistry, M. H. Todd, ''Chem. Central J.'' '''2007''', 1:3. [http://dx.doi.org/10.1186/1752-153X-1-3 Paper]
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Praziquantel Analogues. I. Modification of the Aromatic Ring, F. E. Ronketti, A. V. Ramana, X. Chao-Ming, L. Pica-Mattoccia, D. Cioli and M. H. Todd, ''Bioorg. Med. Chem. Lett.'' '''2007''', ''17'', 4154-4157. [http://dx.doi.org/ Paper]
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The Effects of Drugs, Ions and Poly-L-lysine on the Excretory System of ''Schistosoma mansoni'', J. R. Kusel, F. Oliveira, M. H. Todd, F. Ronketti, S. Lima, A. C.- de Mattos, K. Teixeira, P. M. Z. Coelho, J. A. Thornhill and F. Ribeiro, ''Mem. Inst. Oswaldo Cruz.'' '''2006''', ''101'' (Suppl 1), 293-298. [http://www.scielo.br/scielo.php?script=sci_abstract&pid=S0074-02762006000900046&lng=en&nrm=iso&tlng=en Paper]
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Open Access and Open Source in Chemistry, M. H. Todd, ''Chem. Central J.'' '''2007''', 1:3. [http://dx.doi.org/ Paper]
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Improved Synthesis of the Valuable Peptidomimetic Intermediate 3-Azido-4-hydroxy Cyclopentanoic Acid, E. Tamanini, M. Watkinson and M. H. Todd, ''Tetrahedron Asymmetry'' '''2006''', ''17'', 2235-2239. [http://dx.doi.org/10.1016/j.tetasy.2006.07.001 Paper]
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The Effects of Drugs, Ions and Poly-L-lysine on the Excretory System of ''Schistosoma mansoni'', J. R. Kusel, F. Oliveira, M. H. Todd, F. Ronketti, S. Lima, A. C.- de Mattos, K. Teixeira, P. M. Z. Coelho, J. A. Thornhill and F. Ribeiro, ''Mem. Inst. Oswaldo Cruz.'' '''2006''', ''101'' (Suppl 1), 293-298. [http://dx.doi.org/ Paper]
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Open Source Research – the Power of “Us”, T. B. Kepler, M. A. Marti-Renom, S. M. Maurer, A. K. Rai, G. Taylor and M. H. Todd, ''Aust. J. Chem.'' '''2006''', ''59'', 291-294. [http://dx.doi.org/10.1071/CH06095 Paper]
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Improved Synthesis of the Valuable Peptidomimetic Intermediate 3-Azido-4-hydroxy Cyclopentanoic Acid, E. Tamanini, M. Watkinson and M. H. Todd, ''Tetrahedron Asymmetry'' '''2006''', ''17'', 2235-2239. [http://dx.doi.org/ Paper]
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Solid Phase Synthesis of Praziquantel, S. El-Fayoummy, W. Mansour and M. H. Todd, ''Tetrahedron Lett.'' '''2006''', ''47'', 1287-1290. [http://dx.doi.org/10.1016/j.tetlet.2005.12.073 Paper]
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Open Source Research – the Power of “Us”, T. B. Kepler, M. A. Marti-Renom, S. M. Maurer, A. K. Rai, G. Taylor and M. H. Todd, ''Aust. J. Chem.'' '''2006''', ''59'', 291-294. [http://dx.doi.org/ Paper]
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(R)-4-Hydroxymethyl-2-ferrocenyloxazoline, M. H. Todd, S. El-Fayyoumy, M. E. Motevalli and C. J. Richards, ''Acta Cryst. E.'' '''2006''', ''E62'', m719-m720. [http://dx.doi.org/10.1107/S1600536806006982 Paper]
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Solid Phase Synthesis of Praziquantel, S. El-Fayoummy, W. Mansour and M. H. Todd, ''Tetrahedron Lett.'' '''2006''', ''47'', 1287-1290. [http://dx.doi.org/ Paper]
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Design and Synthesis of New Tetrazolyl- and Carboxy-biphenylylmethyl Quinazoline Derivatives as Angiotensin II AT1 Receptor Antagonists, M. A. H. Ismail, S. Barker, D. A. Abou El Ella, K. A. M. Abouzid and R. A. Toubar and M. H. Todd, ''J. Med. Chem.'' '''2006''', ''49'', 1526-1535. [http://dx.doi.org/10.1021/jm050232e Paper]
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(R)-4-Hydroxymethyl-2-ferrocenyloxazoline, M. H. Todd, S. El-Fayyoumy, M. E. Motevalli and C. J. Richards, ''Acta Cryst. E.'' '''2006''', ''E62'', m719-m720. [http://dx.doi.org/ Paper]
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Computer-Aided Organic Synthesis, M. H. Todd, ''Chem. Soc. Rev.'' '''2005''', ''34'', 247-266. [http://dx.doi.org/10.1039/b104620a  Paper]
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Design and Synthesis of New Tetrazolyl- and Carboxy-biphenylylmethyl Quinazoline Derivatives as Angiotensin II AT1 Receptor Antagonists, M. A. H. Ismail, S. Barker, D. A. Abou El Ella, K. A. M. Abouzid and R. A. Toubar and M. H. Todd, ''J. Med. Chem.'' '''2006''', ''49'', 1526-1535. [http://dx.doi.org/ Paper]
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Drugs for the Control of Parasitic Diseases: Current Status and Development. Schistosomiasis, A. Fenwick, L. Savioli, D. Engels, R. Bergquist and M. H. Todd, ''Trends Parasitol.'' '''2003''', ''19'', 509-515. [http://dx.doi.org/10.1016/j.pt.2003.09.005 Paper]
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Computer-Aided Organic Synthesis, M. H. Todd, ''Chem. Soc. Rev.'' '''2005''', ''34'', 247-266. [http://dx.doi.org/ Paper]
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Asymmetric Autocatalysis: Product Recruitment for the Increase in the Chiral Environment (PRICE), M. H. Todd, ''Chem. Soc. Rev.'' '''2002''', ''31'', 211-222. [http://dx.doi.org/10.1039/b104169j Paper]
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Drugs for the Control of Parasitic Diseases: Current Status and Development. Schistosomiasis, A. Fenwick, L. Savioli, D. Engels, R. Bergquist and M. H. Todd, ''Trends Parasitol.'' '''2003''', ''19'', 509-515. [http://dx.doi.org/ Paper]
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Use of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry in the Tagging of a Combinatorial Library, M. H. Todd and C. Abell, ''Analyst'' '''2002''', ''127'', 1399-1406. [http://dx.doi.org/10.1039/b203957p Paper]
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Asymmetric Autocatalysis: Product Recruitment for the Increase in the Chiral Environment (PRICE), M. H. Todd, ''Chem. Soc. Rev.'' '''2002''', ''31'', 211-222. [http://dx.doi.org/ Paper]
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Amino Acid-Derived Heterocycles: Lewis Acid-Catalyzed and Radical Cyclizations from Peptide Acetals, M. H. Todd, C. O. Ndubaku and P. A. Bartlett, ''J. Org. Chem.'' '''2002''', ''67'', 3985-3988. [http://dx.doi.org/10.1021/jo010990m Paper]
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Use of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry in the Tagging of a Combinatorial Library, M. H. Todd and C. Abell, ''Analyst'' '''2002''', ''127'', 1399-1406. [http://dx.doi.org/ Paper]
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Novel Chemical Tagging Method for Combinatorial Synthesis Utilizing Suzuki Chemistry and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, M. H. Todd and C. Abell, ''J. Comb. Chem.'' '''2001''', ''3'', 319-327. [http://dx.doi.org/10.1021/cc000112m Paper]
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Amino Acid-Derived Heterocycles: Lewis Acid-Catalyzed and Radical Cyclizations from Peptide Acetals, M. H. Todd, C. O. Ndubaku and P. A. Bartlett, ''J. Org. Chem.'' '''2002''', ''67'', 3985-3988. [http://dx.doi.org/ Paper]
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The Attachment and Cleavage of Phenols from Solid Supports, and their Single-bead Mass Spectral Analysis, M. H. Todd and C. Abell, ''Tetrahedron Lett.'' '''2000''', ''41'', 8183-8187. [http://dx.doi.org/10.1016/S0040-4039(00)01431-3 Paper]
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Novel Chemical Tagging Method for Combinatorial Synthesis Utilizing Suzuki Chemistry and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, M. H. Todd and C. Abell, ''J. Comb. Chem.'' '''2001''', ''3'', 319-327. [http://dx.doi.org/ Paper]
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Palladium-catalyzed Carbon-carbon Bond Formation on Solid Support, M. H. Todd and C. Abell, in ''Solid Phase Synthesis'', Burgess, K. (Ed.), Wiley-Interscience (New York), '''2000''', 25-79.
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The Attachment and Cleavage of Phenols from Solid Supports, and their Single-bead Mass Spectral Analysis, M. H. Todd and C. Abell, ''Tetrahedron Lett.'' '''2000''', ''41'', 8183-8187. [http://dx.doi.org/ Paper]
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A Novel Safety-Catch Linker for the Solid Phase Synthesis of Amides and Esters, M. H. Todd, S. F. Oliver and C. Abell, ''Org. Lett.'' '''1999''', ''1'', 1149-1151. [http://dx.doi.org/10.1021/ol990785h Paper]
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Palladium-catalyzed Carbon-carbon Bond Formation on Solid Support, M. H. Todd and C. Abell, in ''Solid Phase Synthesis'', Burgess, K. (Ed.), Wiley-Interscience (New York), '''2000''', 25-79. [http://dx.doi.org/ Paper]
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Synthesis, Characterisation and Reactivity of Aromatic Diboronic Acids, M. H. Todd, S. Balasubramanian and C. Abell, ''Tetrahedron Lett.'' '''1997''', ''38'', 6781-6784. [http://dx.doi.org/10.1016/S0040-4039(97)01552-9 Paper]
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A Novel Safety-Catch Linker for the Solid Phase Synthesis of Amides and Esters, M. H. Todd, S. F. Oliver and C. Abell, ''Org. Lett.'' '''1999''', ''1'', 1149-1151. [http://dx.doi.org/ Paper]
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Synthesis, Characterisation and Reactivity of Aromatic Diboronic Acids, M. H. Todd, S. Balasubramanian and C. Abell, ''Tetrahedron Lett.'' '''1997''', ''38'', 6781-6784. [http://dx.doi.org/ Paper]
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Revision as of 20:12, 4 October 2012

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Papers

Reversing the Triazole Topology in a Cyclam-triazole-dye Ligand Gives a 10-fold Brighter Signal Response to Zn(II) in Aqueous Solution, S. Ast, P. J. Rutledge and M. H. Todd, Eur. J. Inorg. Chem., accepted.

The Outcome of the Oxidations of Unusual Enediamide Motifs is Governed by the Stabilities of the Intermediate Iminium Ions, M. Ahamed, B. Chan and M. H. Todd, PLoS ONE, accepted.

The First Catalytic, Enantioselective Aza-Henry Reaction of an Unactivated Cyclic Imine, N. R. Amarasinghe, P. Turner and M. H. Todd, Adv. Synth. Catal., accepted.

Oxidative Arylation of Isochroman, S. J. Park, J. Price and M. H. Todd, J. Org. Chem. 2012, 77, 949-955. Paper

Copper, Nickel and Zinc Cyclam-amino Acid and Cyclam-peptide Complexes may be Synthesized with “Click” Chemistry and are Non-cytotoxic, M. Yu, J. Price, P. Jensen, T. Shelper, C. Lovitt, S. Duffy, L. Windus, V. Avery, P. J. Rutledge and M. H. Todd, Inorg. Chem. 2011, 50, 12823-12835. Paper

Open Science is a Research Accelerator, M. Woelfle, P. Olliaro and M. H. Todd, Nature Chemistry 2011, 3, 745-748. Paper (mentioned on the cover) Discussed here, in more detail here (mirrored on Faculty of 1000 site) and here. Apparently enjoyed by the Chief Executive of BBSRC!

Resolution of Praziquantel, M. Woelfle, J.-P. Seerden, J. de Gooijer, K. Pouwer, P. Olliaro and M. H. Todd, PLoS Negl. Trop. Dis. 2011, 5(9): e1260. Paper Picked up on the WHO website and evaluated on the F1000 website. A thorough meta-analysis of the project was published.

Polyamide-scorpion Cyclam Lexitropsins Selectively Bind AT-rich DNA Independently of the Nature of the Coordinated Metal, A. T. S. Lo, N. K. Salam, D. E. Hibbs, P. J. Rutledge and M. H. Todd, PLoS One 2011 6(5): e17446. Paper

Chemical Sensors that Incorporate Click-Derived Triazoles, Y. H. Lau, P. J. Rutledge, M. Watkinson and M. H. Todd, Chem. Soc. Rev. 2011 40, 2848-2866. Paper

A DDQ-mediated Oxidative Carbon-carbon Bond Forming Reaction Proceeds via an Isolable Iminium Ion A. S.-K. Tsang, P. Jensen, J. M. Hook, A. S. K. Hashmi and M. H. Todd, Pure Appl. Chem. 2011, 83, 655-665. Paper

A Treasure Hunt for Chemistry, A. J. Bridgeman, R. Connor, P. J. Rutledge and M. H. Todd, J. Chem. Ed. 2011 88, 437-439. Paper Featured in the journal editorial.

A Click Fluorophore Sensor that can Distinguish CuII and HgII via Selective Anion-Induced Demetallation, Y. H. Lau, J. Price, M. H. Todd and P. J. Rutledge, Chem. Eur. J. 2011, 17, 2850-2858. Paper Featured in Chemistry Views and selected as the journal frontispiece.

Gold Catalysis: Reactions of Organogold Compounds with Electrophiles, A. S. K. Hashmi, T. D. Ramamurthi, M. H. Todd, A. S.-K. Tsang and K. Graf, Aust, J. Chem. 2010, 63, 1619-1626. Paper

Aza-Henry Reactions of 3,4-Dihydroisoquinoline, M. Ahamed, T. Thirukkumaran, W. Y. Leung, P. Jensen, J. Schroers and M. H. Todd, Eur. J. Org. Chem. 2010, 5980-5988. Paper

Catalytic, Asymmetric Additions of Carbon-centered Nucleophiles to Nitrogen-containing Heterocycles, M. Ahamed and M. H. Todd, Eur. J. Org. Chem. 2010, 5935-5942. Paper

Cyclam-based "Clickates": Homogeneous and Heterogeneous Fluorescent Sensors for Zn(II), E. Tamanini, K. Flavin, M. Motevalli, S. Piperno, L. A. Gheber, M. H. Todd and M. Watkinson, Inorg. Chem. 2010, 49, 3789-3800. Paper

Can We Measure Catalyst Efficiency in Asymmetric Chemical Reactions? A Theoretical Approach, S. El-Fayyoumy, M. H. Todd and C. J. Richards, Beilstein J. Org. Chem. 2009, 5, No. 67. Paper The Jones group at the University of Sheffield have set up an ACES calculator.

Kernel for Tropical Disease Initiative, L. Orti, R. J. Carbajo, U. Pieper, N. Eswar, S. M. Maurer, A. K. Rai, G. Taylor, M. H. Todd, A. Pineda-Lucena, A. Sali and M. A. Marti-Renom, Nature Biotech. 2009, 27, 320-321. Paper or Link to pdf

Chemotherapeutic Development Strategies for Schistosomiasis, C. R. Caffrey, D. L. Williams, M. H. Todd, D. L. Nelson, J. Keiser and J. Utzinger, in Drug Discovery in Infectious Diseases: from Molecular Targets to Drug Candidates, P. M. Selzer, Ed., 2009, Wiley-VCH, Weinheim. Chapter

Responsive Metal Complexes: A Click-based "Allosteric Scorpionate" Complex Permits the Detection of a Biological Recognition Events by EPR/ENDOR Spectroscopy, E. Tamanini, S. E. J. Rigby, M. Motevalli, M. H. Todd and M. Watkinson, Chem. Eur. J. 2009, 15, 3720-3728. Paper

A Synthetically Simple, Click-generated Cyclam-based Zinc(II) Sensor, E. Tamanini, A. Katewa, L. M. Sedger, M. H. Todd and M. Watkinson, Inorg. Chem. 2009, 48, 319-324. Paper Selected for the cover.

A Kernel for Open Source Drug Discovery in Tropical Diseases, L. Orti, R. J. Carbajo, U. Pieper, N. Eswar, S. M. Maurer, A. K. Rai, G. Taylor, M. H. Todd, A. Pineda-Lucena, A. Sali and M. A. Marti-Renom, PLoS Negl. Trop. Dis. 2009, 3(4): e418. Paper

Facile Synthesis of Vicinal Diamines via Oxidation of N-phenyltetrahydroisoquinolines with DDQ, A.-S. K. Tsang and M. H. Todd, Tetrahedron Lett. 2009, 50, 1199-1202. Paper

Synthesis and DNA Binding Ability of Cyclam-amino Acid Conjugates, A. V. Ramana, M. Watkinson and M. H. Todd, Bioorg. Med. Chem. Lett. 2008, 18, 3007-3010. Paper

Effective Methods for the Biotinylation of Azamacrocycles, S. Krivickas, E. Tamanini, M. H. Todd and M. Watkinson, J. Org. Chem. 2007, 72, 8280-8289. Paper

Is Actin the Praziquantel Receptor?, A. R. Troiani, L. Pica-Mattoccia, C. Valle, D. Cioli, G. Mignogna, F. Ronketti and M. H. Todd, Int. J. Antimicrob. Ag. 2007, 30, 280-281. Paper

Praziquantel Analogues. I. Modification of the Aromatic Ring, F. E. Ronketti, A. V. Ramana, X. Chao-Ming, L. Pica-Mattoccia, D. Cioli and M. H. Todd, Bioorg. Med. Chem. Lett. 2007, 17, 4154-4157. Paper

Open Access and Open Source in Chemistry, M. H. Todd, Chem. Central J. 2007, 1:3. Paper

The Effects of Drugs, Ions and Poly-L-lysine on the Excretory System of Schistosoma mansoni, J. R. Kusel, F. Oliveira, M. H. Todd, F. Ronketti, S. Lima, A. C.- de Mattos, K. Teixeira, P. M. Z. Coelho, J. A. Thornhill and F. Ribeiro, Mem. Inst. Oswaldo Cruz. 2006, 101 (Suppl 1), 293-298. Paper

Improved Synthesis of the Valuable Peptidomimetic Intermediate 3-Azido-4-hydroxy Cyclopentanoic Acid, E. Tamanini, M. Watkinson and M. H. Todd, Tetrahedron Asymmetry 2006, 17, 2235-2239. Paper

Open Source Research – the Power of “Us”, T. B. Kepler, M. A. Marti-Renom, S. M. Maurer, A. K. Rai, G. Taylor and M. H. Todd, Aust. J. Chem. 2006, 59, 291-294. Paper

Solid Phase Synthesis of Praziquantel, S. El-Fayoummy, W. Mansour and M. H. Todd, Tetrahedron Lett. 2006, 47, 1287-1290. Paper

(R)-4-Hydroxymethyl-2-ferrocenyloxazoline, M. H. Todd, S. El-Fayyoumy, M. E. Motevalli and C. J. Richards, Acta Cryst. E. 2006, E62, m719-m720. Paper

Design and Synthesis of New Tetrazolyl- and Carboxy-biphenylylmethyl Quinazoline Derivatives as Angiotensin II AT1 Receptor Antagonists, M. A. H. Ismail, S. Barker, D. A. Abou El Ella, K. A. M. Abouzid and R. A. Toubar and M. H. Todd, J. Med. Chem. 2006, 49, 1526-1535. Paper

Computer-Aided Organic Synthesis, M. H. Todd, Chem. Soc. Rev. 2005, 34, 247-266. Paper

Drugs for the Control of Parasitic Diseases: Current Status and Development. Schistosomiasis, A. Fenwick, L. Savioli, D. Engels, R. Bergquist and M. H. Todd, Trends Parasitol. 2003, 19, 509-515. Paper

Asymmetric Autocatalysis: Product Recruitment for the Increase in the Chiral Environment (PRICE), M. H. Todd, Chem. Soc. Rev. 2002, 31, 211-222. Paper

Use of Fourier Transform Ion Cyclotron Resonance Mass Spectrometry in the Tagging of a Combinatorial Library, M. H. Todd and C. Abell, Analyst 2002, 127, 1399-1406. Paper

Amino Acid-Derived Heterocycles: Lewis Acid-Catalyzed and Radical Cyclizations from Peptide Acetals, M. H. Todd, C. O. Ndubaku and P. A. Bartlett, J. Org. Chem. 2002, 67, 3985-3988. Paper

Novel Chemical Tagging Method for Combinatorial Synthesis Utilizing Suzuki Chemistry and Fourier Transform Ion Cyclotron Resonance Mass Spectrometry, M. H. Todd and C. Abell, J. Comb. Chem. 2001, 3, 319-327. Paper

The Attachment and Cleavage of Phenols from Solid Supports, and their Single-bead Mass Spectral Analysis, M. H. Todd and C. Abell, Tetrahedron Lett. 2000, 41, 8183-8187. Paper

Palladium-catalyzed Carbon-carbon Bond Formation on Solid Support, M. H. Todd and C. Abell, in Solid Phase Synthesis, Burgess, K. (Ed.), Wiley-Interscience (New York), 2000, 25-79.

A Novel Safety-Catch Linker for the Solid Phase Synthesis of Amides and Esters, M. H. Todd, S. F. Oliver and C. Abell, Org. Lett. 1999, 1, 1149-1151. Paper

Synthesis, Characterisation and Reactivity of Aromatic Diboronic Acids, M. H. Todd, S. Balasubramanian and C. Abell, Tetrahedron Lett. 1997, 38, 6781-6784. Paper

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