Todd:Construction
Open science papers being written by us and the people we work with
Synthesis of Analogs of Arylpyrrole Antimalarial Drug Leads This is an undergraduate report describing the synthesis towards analogs of the arylpyrroles, TCMDC 123812 and TCMDC 123794. Raw data in Lablog here
Resolution of Praziquantel - this page is no longer being actively edited since it has been published.
Student-led Optimization of the Resolution of Praziquantel This paper is being written by students participating in the open project whose raw data are here.
Pictet-Spengler route to PZQ - Summary of the Lablog Pictet-Spengler route to Praziquantel
Catalytic, Asymmetric Pictet-Spengler Reaction - A review of the area.
Asymmetric Hydrogenation of PZQ Enamide - New paper describing results on the synthetic approach to (R)-PZQ based on an asymmetric hydrogenation of a precursor enamide.
Papers here are being assembled in the open. Those who make/have made substantial contributions to the projects will be named on the papers, which will be submitted for publication as soon as they're finished. Rules for how this should operate will be posted below but will be adapted from those already established for the Polymath Project
