Tim Frenzel

personal

Welcome to my homepage at OpenWetWare!

I'm a Resident at the Department of Anesthesiology and Intensive Care (H van Aken, MD), University Hospital Muenster,
a Member of the Collaborative Research Center (SFB) 656 MoBil: "Molecular Cardiovascular Imaging - from mouse to man", Muenster, Germany and
a Research Fellow at the Theilmeier Lab.

From 02/2006 until 03/2007 I was doing a Postdoc at Dr. Young/Dr. Yang's lab at the Center for Cerebrovascular Research
at the Department of Anesthesia (R Miller, MD) at University of California, San Francisco (UCSF), CA, USA.


OWW users: send me an email.
email: frenzel (AT) uni-muenster (DOT) de
office: +49 251 83-47255

current address:
Dept. of Anesthesiology and perioperative Intensive Care
Universityhospital Muenster
Albert-Schweitzer-Str. 33
48149 Muenster
Germany

research interests

• modulation of inflammation (e.g. reperfusion injury after myocardial ischemia, cerebral ischemia or circulatory arrest)
  
• molecular and cellular optical imaging in vivo
  
• clinical research in critical care and transfusion medicine
  

bio

current position

• Visiting Postdoc at Dr. Young/Dr. Yang's lab at the Center for Cerebrovascular Research

at the Department of Anesthesia (R Miller, MD) at University of California, San Francisco (UCSF), CA, USA (since 02/2006)

professional training

• member of the Collaborative Research Center (SFB) 656 MoBil: "Molecular Cardiovascular Imaging - from mouse to man", Muenster, Germany (since 07/2005)
• Research fellow at Theilmeier Lab (since 2005)
• Residency at Department of Anesthesiology and Intensive Care (H van Aken, MD) (since 08/2004)
  

education

• Medical School at Friedrich-Schiller-University, Jena, Germany
  
• Medical School at University of Cape Town, South Africa (2003)
  
• Medical School at Universitat Autonoma, Barcelona, Spain (2001)
  
• School for Economics at Friedrich-Schiller-University, Jena, Germany
  

awards

• Kosaka Award, 1st place, IARS (2007)
  
• Kosaka Award, 2nd place, IARS (2006)
  
• AAAS/Science Program for Excellence in Science (2006)
  
• Heinrich-Hertz foundation scholarship, federal state of NRW, Germany (2006)
  
• ERASMUS scholarship (2001)
  
• Special Award, German Nationwide Environmental Competition (1994)
  

professional memberships

• International Anesthesia Research Society (IARS)
  
• German Society for Anesthesiology and Intensive Care Medicine (DGAI)
  
• Subcommitee "Junior Investigators" (DGAI)
  
• American Heart Association
  
• American Association for the Advancement of Science via AAAS/Science Program for Excellence in Science
  

extracurricular activities

• Chief Resident, Dept. of Anesthesiology and perioperative Intensive Care, University Hospital Muenster, Germany (2008-today)
• Member of faculty-parliament, Medical School, Muenster, Germany (2008-today)
• Member of faculty-parliament, Medical School, Jena, Germany (1999-2004)
• Member of senate, Friedrich Schiller-University, Jena, Germany (2002-2003)
• Founding member of EMSA Jena (European Medical Students’ Organization)

Advisory Function on local and european level

publications

(pubmed)

• Zhu W, Fan Y, Frenzel T, Gasmi M, Bartus RT, Young WL, Yang GY, Chen Y. Insulin Growth Factor-1 Gene Transfer Enhances Neurovascular Remodeling and Improves Long-Term Stroke Outcome in Mice. Stroke. 2008 Feb 28 [Epub ahead of print]
  

• Frenzel T, Lee C, Kim H, Quinnine N, Hashimoto T, Lawton M, Guglielmo J, McCulloch C, Young W. Feasibility of minocycline and doxycycline use as potential vasculostatic therapy for brain vascular malformations: pilot study of adverse events and tolerance. Cerebrovasc Dis. 2008;25(1-2):157-63
  

• Larmann J, Schmidt C, Gammelin H, Van Aken HK, Frenzel T, Lanckohr C, Lox M, Boese N, Jurk K, Theilmeier G. ICAM-1-Inhibition ameliorates neurological and hepatic damage after resuscitation in mice. Anesthesiology 2005, 103: 1-6
  

reviews

• Frenzel T, Westphal-Varghese B, Westphal M. Role of storage of red blood cells on microcirclation and tissue oxygenation in critically ill patients. Curr Opin Anaesthesiol. 2009 Apr;22(2):275-80
  

• Frenzel T, Westphal M. [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids= 19307889&query_hl=2&itool=pubmed_docsum

Role of the microcirculation in intensive care and resuscitation: the devil is in the details.] Curr Opin Anaesthesiol. 2009 Apr;22(2):141-2

• Frenzel T, Van Aken H, Westphal M. Our own blood is still the best thing to have in our veins. Curr Opin Anaesthesiol. 2008 Oct;21(5):657-63
  

• Frenzel T, Theilmeier G. Pathophysiology of coronary artery disease and heart failure. Anasthesiol Intensivmed Notfallmed Schmerzther. 2006 May;41(5):315-21
  

case reports and other publications

• Frenzel T, Sibrowski W, Westphal M. Red-cell storage and complications of cardiac surgery. N Engl J Med. 2008 Jun 26;358(26):2841; author reply 2841-2.
  

abstracts

• Frenzel T, Fanxia S, Herzog C, Gabriel R, Larmann J, Lanckohr C, Carmeliet P, Young WL, Theilmeier G, Yang G. Urokinase-type Plasminogen Aktivator Rezeptor (u-PAR) Defizienz reduziert die Infarktgrösse und verbessert das neurologische Outcome nach fokaler zerebraler Ischämie und Reperfusion in der Maus. DAC, Hamburg, Germany 2007
  

• Frenzel T, Larmann J, Schmitz M, Lanckohr C, Theilmeier G, Bremer C. Nicht-Invasives In Vivo Tracking nah-infrarot Fluoreszenz-markierter Makrophagen in Atherosklerotische Läsionen mittels Fluoreszenz-mediierter-Tomographie (FMT). DAC, Hamburg, Germany 2007
  

• Larmann J, Frenzel T, Hahnenkamp A, Swintek A, Bremer C, Theilmeier G. In Vivo Tracking of Macrophage Recruitment into the Inflamed Peritoneum in Mice by Fluorescence Mediated Tomography. IARS 81st Clinical & Scientific Congress, Orlando, FL, USA 2007
  

• Frenzel T, Fanxia S, Larmann J, Young WL, Theilmeier G, Yang G. Urokinase-type Plasminogen Activator Receptor (u-PAR) Deficiency Reduces Infarct Size and Improves Neurological Outcome after Cerbral Ischemia and Reperfusion in Mice. IARS 81st Clinical & Scientific Congress, Orlando, FL, USA 2007
  

• Lanckohr C, Hahnenkamp A, Frenzel T, Mooren FC, Stypmann J, Theilmeier G. Exercise Induced Ventricular Hypertrophy Enlarges Myocardial Damage After Ischemia in Mice. IARS 81st Clinical & Scientific Congress, Orlando, FL, USA 2007
  

• Frenzel T, Larmann J, Schmitz M, Wallbrunn A, Lanckohr C, Theilmeier G, Bremer C. Non-invasive In Vivo Optical Tracking of Macrophage Recruitment to Atherosclerotic Injuries Using Fluorescence Mediated Tomography in Mice . International Stroke Conference, San Francisco, CA, USA 2007
  

• Frenzel T, Schmitz M, Wallbrunn A, Lanckohr C, Bremer C, Theilmeier G. In Vivo Optical Tracking of Macrophage Rrecruitment to Ischemic Myocardium using Fluorescence Mediated Tomography (FMT) in Mice. IARS 80th Clinical & Scientific Congress, San Francisco, CA, USA 2006
  

• Frenzel T, Odyvanova, L., Kroll, T., Sänger, J., Höffken, K., Clement, J.H. und Wöfl, S. Expression of BMPs and BMP associated genes in lung cancer. Deutscher Krebskongress, 2002

links

• protocol collection

• upcoming deadlines

• misc

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