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[[http://openwetware.org/wiki/Theobaldtwang:Contact Contact]]
[[http://openwetware.org/wiki/Theobaldtwang:Contact Contact]]
[[http://openwetware.org/wiki/Theobaldtwang:Education Education]]    [[http://openwetware.org/wiki/Theobaldtwang:Training Training]] [[http://openwetware.org/wiki/Theobaldtwang:Employment Employment]]  [[http://openwetware.org/wiki/Theobaldtwang:Researches Researches]]    '''Grants'''   [[http://openwetware.org/wiki/Theobaldtwang:Publications&patents Publications & Patents]]   [[http://openwetware.org/wiki/Theobaldtwang:Linkout Linkout]]    [[http://openwetware.org/wiki/Theobaldtwang:Hottopics Hottopics]]
[[http://openwetware.org/wiki/Theobaldtwang:Education Education]]    [[http://openwetware.org/wiki/Theobaldtwang:Training Training]] [[http://openwetware.org/wiki/Theobaldtwang:Employment Employment]]  [[http://openwetware.org/wiki/Theobaldtwang:Researches Researches]]    [[http://openwetware.org/wiki/Theobaldtwang:Grants Grants]]   [[http://openwetware.org/wiki/Theobaldtwang:Publications&patents Publications & Patents]] [[http://openwetware.org/wiki/Theobaldtwang:Linkout Linkout]]    [[http://openwetware.org/wiki/Theobaldtwang:Hottopics Hottopics]] [[http://openwetware.org/wiki/Theobaldtwang:Data Data Mining Tool Links]]  
== Grants ==
 
主持项目(as PI)
主持项目(as PI)
 
# 生物法制备新型皮肤修复因子依克多因的研究,安徽工程大学人才引进项目,PI, 编号:2022YQQ063,RMB:300K.
#Spatially engineering the metabolic enzymes in L-Phe biosynthesis, Natural Science Foundation of China, PI ( L-苯丙氨酸的代谢酶空间组织工程研究,国家自然科学基金(青年基金),No.:3100054,2011.1-2013.12,负责人)
# 需钠弧菌中自组装-分泌耦合型蛋白质高效表达体系的构建,安徽省自然科学基金 (Natural Science Foundation of Anhui Province), PI, 编号:2308085MC67, 2023-09-01~2026-08-31, RMB: 100K.
#The glutathionalytion of alcohol dehydrogenase from Candida utilis under oxidative stress , Initiative Fund of Jiangnan University, PI ( 氧化胁迫产朊假丝酵母醇脱氢酶的谷胱甘肽化研究,引进人才启动项目,No.: -,2009-1011,负责人)
#The regulatory mechanism of heterogenous transcriptional factor lpRpoD confering resistance to acetate stress in E.coli, Natural Science Foundation of China-Henan province, PI (1. 异源转录因子lpRpoD调控大肠杆菌抵抗乙酸胁迫的机制研究, '''国家自然科学基金'''-河南联合基金培育项目,编号:U1804100,2019.1-2021.12,第一负责人, RMB 480K )
#Construction of L-phe producer strain with RED recombination and Kan/sacB selective marker,Jiangnan University, PI (利用RED重组和Kan/sacB选择标签构建L-苯丙氨酸生产菌株,教育部高校科研基本业务费(青年探索基金,江南大学),No.: JUSRP10917,2009-2011,负责人)z
#Spatially engineering the metabolic enzymes in L-Phe biosynthesis, Natural Science Foundation of China, PI (2. L-苯丙氨酸生物合成中的代谢酶空间组织工程研究,'''国家自然科学基金青年项目''',编号:3100054,2011.1-2013.12,第一负责人, RMB 190K)
#Novel technology for Large‐scale expression and purification of non-fusion recombinant protein based on the ELP-Intein system,Key Lab of industrial Biotechnology, MOE, PI (基于ELP-Intein体系的新型非融合重组蛋白规模化表达纯化技术,工业生物技术教育部重点实验室开放课题,No.: KLIB-KF201004,2011-2012,负责人)
#Design, construction, and application of platform cell based on transcriptional factor RpoD, PI ( 3. 基于rpoD转录调控的平台细胞设计、构建及应用研究, 信阳师范学院引进人才基金,2018.1-2020.12, 第一负责人,RMB 90K)
#Development of novel functional microbiome strategy for gene resources discovery, University-sponsored program, PI (4. 面向基因资源发掘的功能微生物组策略研究,信阳师范学院自主资助预研项目,2017-2018,  第一负责人,RMB 8K)
#The glutathionalytion of alcohol dehydrogenase from Candida utilis under oxidative stress , Initiative Fund of Jiangnan University, PI ( 5. 氧化胁迫下Candida utilis 中醇脱氢酶的谷胱甘肽化研究,江南大学引进人才基金,2009.1-2010.12.31,第一负责人,RMB 30K)
#Construction of L-phe producer strain with RED recombination and Kan/sacB selective marker,Jiangnan University, PI (6. 利用RED重组和Kan/sacB 选择标签构建L-phe生产菌株,教育部高校基本科研业务费(江南大学),编号:JUSRP10917,2009-2010,第一负责人,RMB 80K)
#Novel technology for Large‐scale expression and purification of non-fusion recombinant protein based on the ELP-Intein system,Key Lab of industrial Biotechnology, MOE, PI (7. 基于ELP-Intein体系的新型非融合重组蛋白规模化表达纯化技术,教育部工业生物技术重点实验室开放课题(江南大学),编号:KLIB-KF201004,2011-2012,第一负责人, RMB 20K)


参与项目(as Participant)
参与项目(as Participant)
#Studies on preclinical pharmaceutics and pharmacological mechanism of the recombinant anti-tumor protein TmSm\Recombinant protein TmSm as theraputic agent and its preclinical study in pharmacology and pharmacokinetics of its anti-cancer activity, Science &Technology Action of Shanghai City,  Shanghai Bureau for Science and Technology,No.:14431904300, 2014.7-2017.9, Key participant (抗肿瘤重组蛋白TmSm临床前药剂学与药理机制研究, 上海市科技局科技行动计划项目,编号:14431904300, 2014.7-2017.9, 参与人)
#谷氨酸棒状杆菌基于甘氨酸代谢调控的5-氨基乙酰丙酸合成研究 ,'''国家自然科学基金青年项目''',编号:31800074,2019.1-2021.12,参与人(2/6),RMB 260K
#Anti-Survivin nanobody prepared with engineered yeast and its activity in antitumor and on stem cells, Municipal Supports for Pujiang Scholors of Shanghai City,Key participant (存活素纳米抗体(Survivin-Nb)工程化酵母制备与抗肺癌及其干细胞活性研究, 上海市人才计划项目,“浦江人才”项目,编号:F200-2R-13110,2013.09.01-2015.8.31,参与人)
#二甲基三硫抑制黄曲霉菌生长和产毒的分子机制研究,'''国家自然科学基金青年项目''',编号:31701740,2018.1-2020.12, 参与人(2/6),RMB 250K
# (解脂亚洛酵母代谢网络异位重构强化alpha-酮戊二酸积累,自然科学基金面上项目,编号:C31171638,2012.1-2015.12,主要参与人)
#海洋菌YM8产二甲基三硫基因克隆与工程菌株构建, '''河南省科技厅''', 编号:182102110018,参与人(2/6),2018-2019,100K
#Study on an Environment-friendly Expression System Based on PFLD1 Promoter from Pichia Pastoris, funded by Natural Science Fund Committee of Shanghai( 基于毕赤酵母PFLD1启动子的“绿色”基因表达体系的研究,上海市自然科学基金项目,编号:05ZR14033,2006.1-2007.9,参与人)
#Studies on preclinical pharmaceutics and pharmacological mechanism of the recombinant anti-tumor protein TmSm \ Recombinant protein TmSm as theraputic agent and its preclinical study in pharmacology and pharmacokinetics of its anti-cancer activity, Science &Technology Action of Shanghai City,  Shanghai Bureau for Science and Technology,No.:14431904300, 2014.7-2017.9, Key participant (抗肿瘤重组蛋白TmSm临床前药剂学与药理机制研究, '''上海市科技局科技行动计划项目''',编号:14431904300, 2014.7-2017.9, 参与人(3/8), RMB 500K)
#Pilot-Scale Research on TAT-Survivin Mutant and Preparation of Test Kit to Detect Highly Hazardous HPV, Bureau of Science and Technology of Shanghai(基因工程抗癌新药TAT-Survivin突变体的中试研究与高危HPV检测试剂盒研究,上海市生物医药科技攻关重点项目,编号:054319928,2006.1-2007.12,参与人)
#Anti-Survivin nanobody prepared with engineered yeast and its activity in antitumor and on stem cells, Municipal Supports for Pujiang Scholors of Shanghai City,No.:F200-2R-13110, 2013.09.01-2015.8.31, Key participant (存活素纳米抗体(Survivin-Nb)工程化酵母制备与抗肺癌及其干细胞活性研究, '''上海市人才计划项目''',“浦江人才”项目,编号:F200-2R-13110,2013.9-2015.8,参与人(3/8), RMB 200K)
#Heterogeneous reconstruction of metabolic network for accumulation of α-Ketoglutaric acid in Yarrowialipolytica, Natural Science Foundation of China, No.:C31171638, 2012.1-2015.12, Key participant(解脂亚洛酵母代谢网络异位重构强化α-酮戊二酸积累,'''国家自然科学基金面上项目''',编号:C31171638,2012.1-2015.12,主要参与人(2/6), RMB 640K)
#Study on an Environment-friendly Expression System Based on PFLD1 Promoter from Pichia Pastoris, funded by Natural Science Fund Committee of Shanghai(基于毕赤酵母PFLD1启动子的“绿色”基因表达体系的研究,'''上海市自然科学基金项目''',编号:05ZR14033,2006.1-2007.9,参与人)
#Pilot-Scale Research on TAT-Survivin Mutant and Preparation of Test Kit to Detect Highly Hazardous HPV, Bureau of Science and Technology of Shanghai(基因工程抗癌新药TAT-Survivin突变体的中试研究与高危HPV检测试剂盒研究,'''上海市生物医药科技攻关重点项目''',编号:054319928,2006.1-2007.12,参与人)
#Platform technologies for large-scale production of protein drug using microbial expression system, Ministry of Science and Technology of China(生物技术制药重大专项“微生物表达蛋白药物规模化制备平台技术”,科技部“863”计划,编号:2004AA2Z3801,参与人)
#Platform technologies for large-scale production of protein drug using microbial expression system, Ministry of Science and Technology of China(生物技术制药重大专项“微生物表达蛋白药物规模化制备平台技术”,科技部“863”计划,编号:2004AA2Z3801,参与人)
#Preparation of Immunological Test Kit to Detect Mycotoxin DON (Deoxynivalenol, DON) in Agricultural Products, Bureau of Science and Technology, Fujian Province(农产品中真菌毒素DON免疫检测试剂盒的开发,福建省科技厅项目,2001-2003,参与人)
#Preparation of Immunological Test Kit to Detect Mycotoxin DON (Deoxynivalenol, DON) in Agricultural Products, Bureau of Science and Technology, Fujian Province(农产品中真菌毒素DON免疫检测试剂盒的开发,福建省科技厅项目,2001-2003,参与人)


其他 (Others)
其他 (Others)
#Novel high efficient DNA ligation system, Creation Practice of Undergraduate Student, No.:x14019, 2014.12-2015.12, Team: Xie Ye, Xue Jiayun, Shi Xiaona, Xu Ying, Director ( 高效DNA连接体系的创建, 大学生创新实践活动,编号:X14019, 成员:谢晔,薛佳韵,师晓娜,许滢,指导者:王天文)
#Novel high efficient DNA ligation system, Creation Practice of Undergraduate Student, No.:x14019, 2014.12-2015.12, Team: Xie Ye, Xue Jiayun, Shi Xiaona, Xu Ying, Director (高效DNA连接体系的创建, 大学生创新实践活动,编号:X14019,成员:谢晔,薛佳韵,师晓娜,许滢;指导老师:王天文)
 
Updated at 15:38 2018/12/14

Latest revision as of 23:42, 15 October 2023

[Contact] [Education] [Training] [Employment] [Researches] [Grants] [Publications & Patents] [Linkout] [Hottopics] [Data Mining Tool Links]

主持项目(as PI)

  1. 生物法制备新型皮肤修复因子依克多因的研究,安徽工程大学人才引进项目,PI, 编号:2022YQQ063,RMB:300K.
  2. 需钠弧菌中自组装-分泌耦合型蛋白质高效表达体系的构建,安徽省自然科学基金 (Natural Science Foundation of Anhui Province), PI, 编号:2308085MC67, 2023-09-01~2026-08-31, RMB: 100K.
  3. The regulatory mechanism of heterogenous transcriptional factor lpRpoD confering resistance to acetate stress in E.coli, Natural Science Foundation of China-Henan province, PI (1. 异源转录因子lpRpoD调控大肠杆菌抵抗乙酸胁迫的机制研究, 国家自然科学基金-河南联合基金培育项目,编号:U1804100,2019.1-2021.12,第一负责人, RMB 480K )
  4. Spatially engineering the metabolic enzymes in L-Phe biosynthesis, Natural Science Foundation of China, PI (2. L-苯丙氨酸生物合成中的代谢酶空间组织工程研究,国家自然科学基金青年项目,编号:3100054,2011.1-2013.12,第一负责人, RMB 190K)
  5. Design, construction, and application of platform cell based on transcriptional factor RpoD, PI ( 3. 基于rpoD转录调控的平台细胞设计、构建及应用研究, 信阳师范学院引进人才基金,2018.1-2020.12, 第一负责人,RMB 90K)
  6. Development of novel functional microbiome strategy for gene resources discovery, University-sponsored program, PI (4. 面向基因资源发掘的功能微生物组策略研究,信阳师范学院自主资助预研项目,2017-2018, 第一负责人,RMB 8K)
  7. The glutathionalytion of alcohol dehydrogenase from Candida utilis under oxidative stress , Initiative Fund of Jiangnan University, PI ( 5. 氧化胁迫下Candida utilis 中醇脱氢酶的谷胱甘肽化研究,江南大学引进人才基金,2009.1-2010.12.31,第一负责人,RMB 30K)
  8. Construction of L-phe producer strain with RED recombination and Kan/sacB selective marker,Jiangnan University, PI (6. 利用RED重组和Kan/sacB 选择标签构建L-phe生产菌株,教育部高校基本科研业务费(江南大学),编号:JUSRP10917,2009-2010,第一负责人,RMB 80K)
  9. Novel technology for Large‐scale expression and purification of non-fusion recombinant protein based on the ELP-Intein system,Key Lab of industrial Biotechnology, MOE, PI (7. 基于ELP-Intein体系的新型非融合重组蛋白规模化表达纯化技术,教育部工业生物技术重点实验室开放课题(江南大学),编号:KLIB-KF201004,2011-2012,第一负责人, RMB 20K)

参与项目(as Participant)

  1. 谷氨酸棒状杆菌基于甘氨酸代谢调控的5-氨基乙酰丙酸合成研究 ,国家自然科学基金青年项目,编号:31800074,2019.1-2021.12,参与人(2/6),RMB 260K
  2. 二甲基三硫抑制黄曲霉菌生长和产毒的分子机制研究,国家自然科学基金青年项目,编号:31701740,2018.1-2020.12, 参与人(2/6),RMB 250K
  3. 海洋菌YM8产二甲基三硫基因克隆与工程菌株构建, 河南省科技厅, 编号:182102110018,参与人(2/6),2018-2019,100K
  4. Studies on preclinical pharmaceutics and pharmacological mechanism of the recombinant anti-tumor protein TmSm \ Recombinant protein TmSm as theraputic agent and its preclinical study in pharmacology and pharmacokinetics of its anti-cancer activity, Science &Technology Action of Shanghai City, Shanghai Bureau for Science and Technology,No.:14431904300, 2014.7-2017.9, Key participant (抗肿瘤重组蛋白TmSm临床前药剂学与药理机制研究, 上海市科技局科技行动计划项目,编号:14431904300, 2014.7-2017.9, 参与人(3/8), RMB 500K)
  5. Anti-Survivin nanobody prepared with engineered yeast and its activity in antitumor and on stem cells, Municipal Supports for Pujiang Scholors of Shanghai City,No.:F200-2R-13110, 2013.09.01-2015.8.31, Key participant (存活素纳米抗体(Survivin-Nb)工程化酵母制备与抗肺癌及其干细胞活性研究, 上海市人才计划项目,“浦江人才”项目,编号:F200-2R-13110,2013.9-2015.8,参与人(3/8), RMB 200K)
  6. Heterogeneous reconstruction of metabolic network for accumulation of α-Ketoglutaric acid in Yarrowialipolytica, Natural Science Foundation of China, No.:C31171638, 2012.1-2015.12, Key participant(解脂亚洛酵母代谢网络异位重构强化α-酮戊二酸积累,国家自然科学基金面上项目,编号:C31171638,2012.1-2015.12,主要参与人(2/6), RMB 640K)
  7. Study on an Environment-friendly Expression System Based on PFLD1 Promoter from Pichia Pastoris, funded by Natural Science Fund Committee of Shanghai(基于毕赤酵母PFLD1启动子的“绿色”基因表达体系的研究,上海市自然科学基金项目,编号:05ZR14033,2006.1-2007.9,参与人)
  8. Pilot-Scale Research on TAT-Survivin Mutant and Preparation of Test Kit to Detect Highly Hazardous HPV, Bureau of Science and Technology of Shanghai(基因工程抗癌新药TAT-Survivin突变体的中试研究与高危HPV检测试剂盒研究,上海市生物医药科技攻关重点项目,编号:054319928,2006.1-2007.12,参与人)
  9. Platform technologies for large-scale production of protein drug using microbial expression system, Ministry of Science and Technology of China(生物技术制药重大专项“微生物表达蛋白药物规模化制备平台技术”,科技部“863”计划,编号:2004AA2Z3801,参与人)
  10. Preparation of Immunological Test Kit to Detect Mycotoxin DON (Deoxynivalenol, DON) in Agricultural Products, Bureau of Science and Technology, Fujian Province(农产品中真菌毒素DON免疫检测试剂盒的开发,福建省科技厅项目,2001-2003,参与人)

其他 (Others)

  1. Novel high efficient DNA ligation system, Creation Practice of Undergraduate Student, No.:x14019, 2014.12-2015.12, Team: Xie Ye, Xue Jiayun, Shi Xiaona, Xu Ying, Director (高效DNA连接体系的创建, 大学生创新实践活动,编号:X14019,成员:谢晔,薛佳韵,师晓娜,许滢;指导老师:王天文)

Updated at 15:38 2018/12/14