Talk:Todd:Catalytic, Asymmetric Pictet-Spengler Reaction: Difference between revisions
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Matthew Todd (talk | contribs) (→KAB attempt to understand 2000 Koomen OrgLett: Archived KAB discussion of Koomen) |
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We can use this page for discussion. May need to preface things with initials. | We can use this page for discussion. May need to preface things with initials. | ||
Archived/inactive discussions: | |||
''1. KAB attempt to understand 2000 Koomen OrgLett'' (archived since this paper no longer included) | |||
The figure for Table 1 gives diasteromeric ratios. Where are the diastereomers? I only the possibility for enantiomers in the product. Where's the other stereogenic centre? | The figure for Table 1 gives diasteromeric ratios. Where are the diastereomers? I only the possibility for enantiomers in the product. Where's the other stereogenic centre? | ||
Revision as of 04:39, 19 January 2012
We can use this page for discussion. May need to preface things with initials.
Archived/inactive discussions:
1. KAB attempt to understand 2000 Koomen OrgLett (archived since this paper no longer included)
The figure for Table 1 gives diasteromeric ratios. Where are the diastereomers? I only the possibility for enantiomers in the product. Where's the other stereogenic centre?
They also mentioned "hydrolysis of the starting material" numerous times. I'm assuming they mean hydrolysis of the N-S bond (there doesn't seem any other reasonable place for hydrolysis of the SM to occur), but I just wanted to check.
Interesting that the chirality of CSA doesn't affect the ee. Unlike the conjugate BINOL base acting as the counterion in Dixon 2010.
