Talk:CH391L/S2013 Hala Ouzon Jan 23 2013: Difference between revisions

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*'''[[User:Tanya_E_Raymond|Tanya Raymond]] 15:48, 23 January 2013 (EST)''' What are other roles of BRCA2 in humans?
*'''[[User:Tanya_E_Raymond|Tanya Raymond]] 15:48, 23 January 2013 (EST)''' What are other roles of BRCA2 in humans?
*'''[[User:Tanya_E_Raymond|Tanya Raymond]] 15:48, 23 January 2013 (EST)''' Are there other proteins that interact with Rad51 and assist with exchange between Rad51 and RPA at ssDNA?
*'''[[User:Tanya_E_Raymond|Tanya Raymond]] 15:48, 23 January 2013 (EST)''' Are there other proteins that interact with Rad51 and assist with exchange between Rad51 and RPA at ssDNA?
*'''[[User:Logan_R._Myler|Logan Myler]]''' Both RPA and Rad51 are single-stranded DNA binding proteins homologous to SSB and RecA in E. Coli respectively.  Without BRCA2, how does E. coli displace SSB(RPA), and why is BRCA2 important for mammalian cells?  In general, what is the importance of having both RPA and Rad51 instead of one single-stranded DNA binding protein that can promote homologous recombination?
*'''[[User:Logan_R._Myler|Logan Myler]]''' Both RPA and Rad51 are single-stranded DNA binding proteins homologous to SSB and RecA in E. coli respectively.  Without BRCA2, how does E. coli displace SSB(RPA), and why is BRCA2 important for mammalian cells?  In general, what is the importance of having both RPA and Rad51 instead of one single-stranded DNA binding protein that can promote homologous recombination?


#REDIRECT [[CH391L/S2013 Hala Ouzon Jan 23 2013]]
#REDIRECT [[CH391L/S2013 Hala Ouzon Jan 23 2013]]

Revision as of 12:56, 29 January 2013

  • Tanya Raymond 15:48, 23 January 2013 (EST) What are other roles of BRCA2 in humans?
  • Tanya Raymond 15:48, 23 January 2013 (EST) Are there other proteins that interact with Rad51 and assist with exchange between Rad51 and RPA at ssDNA?
  • Logan Myler Both RPA and Rad51 are single-stranded DNA binding proteins homologous to SSB and RecA in E. coli respectively. Without BRCA2, how does E. coli displace SSB(RPA), and why is BRCA2 important for mammalian cells? In general, what is the importance of having both RPA and Rad51 instead of one single-stranded DNA binding protein that can promote homologous recombination?
  1. REDIRECT CH391L/S2013 Hala Ouzon Jan 23 2013
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