Talk:CH391L/S13/In vitro Selection of FNAs

FNAs Talk

• Kevin Baldridge 17:24, 11 February 2013 (EST):The first thing I see is that small non-coding RNAs are not represented in this group. Maybe it would be a good idea to add a section about prokaryotic small RNAs or eukaryotic micro- or piwi-interacting RNAs that are involved in pre-translational regulation.

• Benjamin Gilman 17:59, 11 February 2013 (EST): There's been been some work done on evolving deoxyribozymes (with or without unnatural bases) that catalyze a range of organic and inorganic synthesis reactions. Checking out some papers from Bruce Eaton might be a good place to start.

• Alvaro E. Rodriguez M. 21:16, 11 February 2013 (EST):Hello Kevin he reason why none of the small non-coding RNAs are mentioned is that they do no perform any type of catalysis/ligand binding on their own.
• Alvaro E. Rodriguez M. 21:16, 11 February 2013 (EST): Hey, Ben do you happen to have a copy of the RNA world article were you mention RNase P as being discovered much earlier. I also appreciate the link to the Bruce Eaton page as it would be helpful to include his work in this wiki page.

• Gabriel Wu 02:10, 14 February 2013 (EST): You have a note to self about including a discussion on RNA world. Include or move to talk section.

• Gabriel Wu 02:10, 14 February 2013 (EST): Ribozyme section is numbered twice.

• Gabriel Wu 02:10, 14 February 2013 (EST): Could you add a conclusion and/or a future directions section to put the topic in context?

• Max E. Rubinson 11:03, 14 February 2013 (EST): Can you update this page to include a more detailed discussion of in vitro selection methods and maybe discuss some potential applications of functional nucleic acids?