THF
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(Difference between revisions)
(→N-substituted (cis/trans) phenoxyalkylation using Michael reaction of complex amino acids) |
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* Benzylamine | * Benzylamine | ||
* Isopropanol | * Isopropanol | ||
| + | * [[Piperidine]] | ||
== References == | == References == | ||
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* Michael reaction | * Michael reaction | ||
* Pictet-Spengler reaction | * Pictet-Spengler reaction | ||
| - | + | * [[DMF]] - A THF analog (N,N-dimethylformamide) | |
[[Category:Chemical]] | [[Category:Chemical]] | ||
Revision as of 11:46, 15 January 2013
Contents |
Name
Tetrahydrofuran
Use
Heterocyclic compound implicated in organic synthesis of unnatural amino acids, and most importantly as a miscible (anhydrous) reagent to synthetize N-substituted phenoxyalkylamines (ligands) using orthogonal (multi-step) catalysis of dicarboxilic protected C=C ions (amines) in liquid phase PTC/Ion chromatography.
N-substituted (cis/trans) phenoxyalkylation using Michael reaction of complex amino acids
- a "alkane isomerisation" type of organic catalysis 1
- Etienne Robillard 10:35, 15 January 2013 (EST) Can aromatic nucleophilic substitution of a disubstituted phenoxyalkylamine produce para/ortho opioid ligand (L-dopamine for example) ? In this case, verify if the N heterocycle ring is acting as the nucleophile (R) reagent in presence of an aldehyde...
- Etienne Robillard 10:35, 15 January 2013 (EST) See also "Michael reaction" for a proper explanation.. :)
- Etienne Robillard 10:35, 15 January 2013 (EST) Can aromatic nucleophilic substitution of a disubstituted phenoxyalkylamine produce para/ortho opioid ligand (L-dopamine for example) ? In this case, verify if the N heterocycle ring is acting as the nucleophile (R) reagent in presence of an aldehyde...
- isopropanol can donate proton -- an aldehyde like solvent?
- Etienne Robillard 10:35, 15 January 2013 (EST) Can THF donate stuff with nucleophilic rings? ie cyclohexanoyl
- alkane isomerisation = organic synthesis: L-dopamine, cyclohexylamine, etc..
- Ethics of producing novel opioid receptor agonist compounds for human-specific psychotropic experiments?
- Etienne Robillard 10:35, 15 January 2013 (EST) Heck, is there a possibility theses novel psychotropic compounds be used by terrorist groups to terrorize unwary citizens with psychological warfare using unconventional (synthetic) "devices" ?
Related chemicals
- Benzylamine
- Isopropanol
- Piperidine
References
1. Kim J., Recent Advances in Asymmetric Phase-Transfer-Catalysis, 2011 http://stoltz.caltech.edu/seminars/2011_Kim.pdf p. [1-25]
See also
- Michael reaction
- Pictet-Spengler reaction
- DMF - A THF analog (N,N-dimethylformamide)
