TB Breath Test Proposal

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(20.109 Research Proposal Pink WF)
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Hey fellow 109ers! This is our proposal!
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20.109 WF Pink Team Research Proposal
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TB Breath Test
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'''Project Overview:'''
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'''Background'''
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''-Disease background''
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-Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis
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-can be fatal
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-usually affects the lungs, but can also affect brain, kidneys, spine
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-symptoms include weight loss, night sweats, fever, chills, coughing (blood), chest pain
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-latent vs active infection
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-becomes active if immune system cannot repress growth
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-5-10% of latent cases will become active
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''-2 widely used current tests:''
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-Mantoux TB skin test injects a small amount of tuberculin into the skin
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-patient must return to clinic 48/72 hours later for evaluation of injection site
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-TB blood test (interferon-gamma release assay) measures immune system reaction to TB bacteria
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'''Problem/Goals Statement:'''
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'''Details/Method:'''
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'''
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Predicted Outcomes:'''
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'''Resources:'''

Revision as of 21:38, 3 December 2013

20.109 WF Pink Team Research Proposal

TB Breath Test

Project Overview:

Background -Disease background -Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis -can be fatal -usually affects the lungs, but can also affect brain, kidneys, spine -symptoms include weight loss, night sweats, fever, chills, coughing (blood), chest pain -latent vs active infection -becomes active if immune system cannot repress growth -5-10% of latent cases will become active

-2 widely used current tests: -Mantoux TB skin test injects a small amount of tuberculin into the skin -patient must return to clinic 48/72 hours later for evaluation of injection site -TB blood test (interferon-gamma release assay) measures immune system reaction to TB bacteria

Problem/Goals Statement:

Details/Method:

Predicted Outcomes:

Resources:

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