Synthetic Biology:Semantic web ontology/Examples: Difference between revisions

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==Life Sciences==
==Life Sciences==
#[http://geneontology.org/ Gene Ontology] provides a controlled vocabulary to describe gene and gene product attributes in any organism. GO terms are organized in directed acyclic graphs (DAGs), which differ from hierarchies in that a 'child' (more specialized term) can have many 'parents' (less specialized terms). GO terms are connected by 'is a' (generalizations) and 'part of' (composition) relationships.
*[http://geneontology.org/ Gene Ontology] provides a controlled vocabulary to describe gene and gene product attributes in any organism. GO terms are organized in directed acyclic graphs (DAGs), which differ from hierarchies in that a 'child' (more specialized term) can have many 'parents' (less specialized terms). GO terms are connected by 'is a' (generalizations) and 'part of' (composition) relationships.
#*Namespace: ftp://ftp.geneontology.org/pub/go/xml/dtd/go.dtd
**Namespace: ftp://ftp.geneontology.org/pub/go/xml/dtd/go.dtd
#*Properties: name, definition, isa, association, evidence
**Properties: name, definition, isa, association, evidence
#[http://song.sourceforge.net/so.shtml Sequence Ontology]: features on a nucleotide or protein sequence
*[http://song.sourceforge.net/so.shtml Sequence Ontology]: features on a nucleotide or protein sequence
#[http://www.biopax.org/ BioPAX]: biological pathway data
*[http://www.biopax.org/ BioPAX]: biological pathway data
#[http://www.isb-sib.ch/~ejain/rdf/ UniProt] protein sequence and annotation data in RDF format. [http://www.isb-sib.ch/~ejain/rdf/owl/ UniProt OWL Ontology]
*[http://www.isb-sib.ch/~ejain/rdf/ UniProt] protein sequence and annotation data in RDF format. [http://www.isb-sib.ch/~ejain/rdf/owl/ UniProt OWL Ontology]
#[http://sbml.org/documents/ SBML] uses [http://www.cellml.org/specifications/archive/metadata/20011102/cellml_metadata_specification.html CellML metadata] to describe its elements. See also a [http://www.sbml.org/forums/index.php?t=msg&goto=1435&rid=0#msg_1435 message] on SBML forum.
*[http://sbml.org/documents/ SBML] uses [http://www.cellml.org/specifications/archive/metadata/20011102/cellml_metadata_specification.html CellML metadata] to describe its elements. See also a [http://www.sbml.org/forums/index.php?t=msg&goto=1435&rid=0#msg_1435 message] on SBML forum.
#[http://biomodels.net/ BioModels] database and Systems Biology Ontologies (SBO) project
*[http://biomodels.net/ BioModels] database and Systems Biology Ontologies (SBO) project
#[http://obo.sourceforge.net/ Open Biomedical Ontologies]
*[http://obo.sourceforge.net/ Open Biomedical Ontologies]
#[http://anil.cchmc.org/Bio-Ontologies.html Bio-Ontologies]
*[http://anil.cchmc.org/Bio-Ontologies.html Bio-Ontologies]
#[http://www.bioinfo.de/isb/2002/02/0017/main.html Ontologies for molecular biology and bioinformatics]
*[http://www.bioinfo.de/isb/2002/02/0017/main.html Ontologies for molecular biology and bioinformatics]
#[http://mged.sourceforge.net/ontologies/ Microarray Gene Expression Society (MGED) Ontology]
*[http://mged.sourceforge.net/ontologies/ Microarray Gene Expression Society (MGED) Ontology]
#[http://www.schemaweb.info/ RDF Schemas directory]
*[http://www.schemaweb.info/ RDF Schemas directory]
#[http://www.co-ode.org/ontologies/ CO-ODE ontology examples]
*[http://www.co-ode.org/ontologies/ CO-ODE ontology examples]
#*[http://smi-protege.stanford.edu:8080/KnowledgeZone/ KnowledgeZone] - peer reviewed ontology library
**[http://smi-protege.stanford.edu:8080/KnowledgeZone/ KnowledgeZone] - peer reviewed ontology library
*[http://www.onto-med.de/ Onto-Med] research group: ontologies in medicine


Diagram of synthetic biology ontology v0.01 (developed using existing terminology described on the [http://parts2.mit.edu/r/parts/partsdb/index.cgi Registry website]):
Diagram of synthetic biology ontology v0.01 (developed using existing terminology described on the [http://parts2.mit.edu/r/parts/partsdb/index.cgi Registry website]):

Revision as of 13:09, 26 April 2006

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Ontology - essentially, a formal description of objects and their interrelationships Described using RDF Schema and/or OWL.

Life Sciences

Diagram of synthetic biology ontology v0.01 (developed using existing terminology described on the Registry website):

Upper ontologies

Metadata applications

  • Google Base
  • Biozon - a unified biological resource on DNA sequences, proteins, complexes and cellular pathways. The information in Biozon is logically represented as a graph in which nodes represent some unit of data, and edges indicate a relationship between two nodes.
  • Open Directory RDF dump The Open Directory Project is the largest, most comprehensive human-edited directory of the Web. It is constructed and maintained by a vast, global community of volunteer editors.

Resources

  1. GO annotation wiki (from Sri)
  2. Ontology Development 101: A Guide to Creating Your First Ontology - what is an ontology and why we need it
  3. Protégé OWL Tutorial (PDF)
  4. Manchester Pizza Finder
  5. National Center for Biomedical Ontology

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