SynBERC:Seminar series/Remy Chait

From OpenWetWare

Jump to: navigation, search

Antibacterial drug combinations and evolution of drug resistance
Remy Chait, Harvard Systems Biology
April 24, 2007
12-1pm
68-181, MIT

The rapid evolution of bacterial drug resistance and the alarming slowdown in development of new antibiotics is spurring attention towards multi-drug treatments. But how do such treatments affect the rate of evolution of drug resistance? I will present a simple model and direct experimental measurements showing that non-additive interactions between the drugs can profoundly alter the fitness landscape, leading to surprising and counterintuitive outcomes.

Reference

  1. Chait R, Craney A, and Kishony R. . pmid:17410176. PubMed HubMed [Chait-Nature-2007]

Remote participation

To submit questions during the talk, you must have an OpenWetWare account. Type questions into the chat room.

A video stream of the talk will be available for real-time viewing. Just point Quicktime or VLC to the following stream: 

rtsp://caprica.csail.mit.edu/SynBERC.sdp


Archived video

A copy of the talk is available at blip.tv. It is also embedded below (follow the previous link to blip.tv for other formats):


Click To Play

Retrieved from "http://openwetware.org/wiki/SynBERC:Seminar_series/Remy_Chait"
Personal tools