SynBERC:Seminar series/Remy Chait: Difference between revisions
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==Remote participation== | ==Remote participation== | ||
To submit questions during the talk, you must have an [[Join|OpenWetWare account]]. Type questions into the [[Special:Chat |chat room]]. | |||
A video stream of the talk will be available for real-time viewing. Just point Quicktime or [http://www.videolan.org/vlc/ VLC] to the following stream: | |||
'''rtsp://caprica.csail.mit.edu/SynBERC.sdp''' | |||
Revision as of 08:49, 24 April 2007
Antibacterial drug combinations and evolution of drug resistance
Remy Chait, Harvard Systems Biology
April 24, 2007
12-1pm
68-181, MIT
The rapid evolution of bacterial drug resistance and the alarming slowdown in development of new antibiotics is spurring attention towards multi-drug treatments. But how do such treatments affect the rate of evolution of drug resistance? I will present a simple model and direct experimental measurements showing that non-additive interactions between the drugs can profoundly alter the fitness landscape, leading to surprising and counterintuitive outcomes.
Reference
- Chait R, Craney A, and Kishony R. Antibiotic interactions that select against resistance. Nature. 2007 Apr 5;446(7136):668-71. DOI:10.1038/nature05685 |
Remote participation
To submit questions during the talk, you must have an OpenWetWare account. Type questions into the chat room.
A video stream of the talk will be available for real-time viewing. Just point Quicktime or VLC to the following stream:
rtsp://caprica.csail.mit.edu/SynBERC.sdp
