SynBERC:MIT
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SynBERC Research @ MIT
Short summaries of MIT SynBERC research projects.
Lab Video Tours
Synthetic Biology Working Group lunches
Current information about SBWG Lunches is located at SBWGLunches.
Information pre-2010 can be found at SynBERC:SBWGLunchesArchive.
Previous meetings
- SynBERC:MIT/Calendar/2008-6-18: ??th of restarted MIT SBWG lunch
- Wednesday 6/18 (2:00-2:00p EST), 32-D463, MIT
- SynBERC:MIT/Calendar/2008-3-26: 69th of restarted MIT SBWG lunch
- Wednesday 3/26 (4:00-5:00p EST), 32-D463, MIT
- SynBERC:MIT/Calendar/2008-3-19: 68th of restarted MIT SBWG lunch
- Wednesday 3/19 (12:00-1:00p EST), 32-D463, MIT
- SynBERC:MIT/Calendar/2008-3-12: 67th of restarted MIT SBWG lunch
- Wednesday 3/12 (1:00-2:00p EST), 32-D463, MIT
- SynBERC:MIT/Calendar/2008-2-27: 66th of restarted MIT SBWG lunch
- Wednesday 2/27 (1:00-2:00p EST), 32-D463, MIT
- SynBERC:MIT/Calendar/2008-2-20: 65th of restarted MIT SBWG lunch
- Wednesday 2/20 (1:00-2:00p EST), 32-D463, MIT
- SynBERC:MIT/Calendar/2008-2-14: 64th of restarted MIT SBWG lunch
- Thursday 2/14 (1:00-2:00p EST), 68-180, MIT
- SynBERC:MIT/Calendar/2008-2-6: 63th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2008-1-23: 62th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-1-16: 61th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-1-9: 60th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-12-19: 59th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-12-12: 58th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-12-5: 57th of restarted MIT SBWG lunch
- Wednesday 11/28 (11:00a-12:00p EST), 68-181, MIT
- SynBERC:MIT/Calendar/2007-11-28: 56th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-11-14: 55th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-11-7: 54th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-10-31: 53th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-10-24: 52th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-10-17: 51th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-10-10: 50th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-10-3: 49th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-9-26: 48th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-9-19: 47th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-9-12: 46th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-9-5: 45th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-8-29: 44th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-8-22: 43th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-8-15: 42th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-8-8: 41th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-8-1: 40th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-7-25: 39th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-7-18: 38th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-7-11: 37th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-6-20: 36th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-6-13: 35th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-6-6: 34th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-5-30: 33th of restarted MIT SBWG lunch
- Wednesday 5/30 (12:30-1:30p EST), 68-181, MIT
- SynBERC:MIT/Calendar/2007-5-22: 32th of restarted MIT SBWG lunch
- Tuesday 5/22 (12-1p EST), 56-614, MIT
- SynBERC:MIT/Calendar/2007-5-15: 31th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-5-8: 30th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-5-1: 29th of restarted MIT SBWG lunch
- SynBERC:Seminar series/Remy Chait: 28th of restarted MIT SBWG lunch
- Tuesday 4/24 (12-1p EST), 68-181, MIT
- SynBERC:MIT/Calendar/2007-4-17: 27th of restarted MIT SBWG lunch
- Tuesday 4/17 (12-1p EST), Meet at 320 Charles St Cambridge, MA 02141 at 12pm
- SynBERC:MIT/Calendar/2007-4-10: 26th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-4-3: 25th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-3-28: 24th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-3-20: 23th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-3-13: 22th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-3-6: 21th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-2-27: 20th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-2-13: 19th of restarted MIT SBWG lunch
- Tuesday 2/13 (12-1p), 68-181, MIT
- SynBERC:MIT/Calendar/2007-2-6: 18th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-1-31: 17th of restarted MIT SBWG lunch
- SynBERC:MIT/Calendar/2007-1-24: 16th of restarted MIT SBWG lunch
- Wednesday 1/24 (1-2p), 56-614, MIT
- SynBERC:MIT/Calendar/2007-1-17: 15th of restarted MIT SBWG lunch
- Wednesday 1/17 (1-2p), 56-614, MIT
- SynBERC:MIT/Calendar/2007-1-10: 14th of restarted MIT SBWG lunch
- Wednesday 1/10 (1-2p), 32-G449, MIT
- SynBERC:MIT/Calendar/2006-12-20: 13th of restarted MIT SBWG lunch
- Wednesday 12/20 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-12-13: 12th of restarted MIT SBWG lunch
- Wednesday 12/13 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-12-6: 11th of restarted MIT SBWG lunch
- Wednesday 12/06 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-11-29: 10th of restarted MIT SBWG lunch
- Wednesday 11/29 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-11-15: 9th of restarted MIT SBWG lunch
- Wednesday 11/15 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-11-08: 8th of restarted MIT SBWG lunch
- Wednesday 11/08 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-11-01: 7th of restarted MIT SBWG lunch
- Wednesday 11/01 (1-2p), 32-G449, MIT
- SynBERC:MIT/Calendar/2006-10-25: 6th of restarted MIT SBWG lunch
- Wednesday 10/25 (1-2p), 32-G449, MIT
- SynBERC:MIT/Calendar/2006-10-18: 5th of restarted MIT SBWG lunch
- Wednesday 10/18 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-10-11: 4th of restarted MIT SBWG lunch
- Wednesday 10/11 (1-2p), 32-G449 (Kiva conference room), MIT
- SynBERC:MIT/Calendar/2006-10-4: 3rd of restarted MIT SBWG lunch
- Wednesday 10/4 (1-2p), 68-180, MIT
- SynBERC:MIT/Calendar/2006-9-27: 2nd of restarted MIT SBWG lunch
- Wednesday 9/27 (1-2p), 32-D463, MIT
- SynBERC:MIT/Calendar/2006-9-20: 1st of restarted MIT SBWG lunch
- Wednesday 9/20 (1-2p), 32-G449
- Please feel free to add yourself to the agenda.
- SynBERC:MIT/Calendar/2006-8-30: Kickoff Meeting @ MIT
- Wednesday 8/30 (4-5p), 68-574 or immediately local surrogate
Proposed topics
Past and present research topics for synthetic biology working group lunches. Please add to the list.
- Electronics device families (introduction by TK) - SynBERC:MIT/Calendar/2006-9-27
- Abstraction hierarchies
- Parts -> Devices -> Systems
- Biological layer model (AC)
- DEVICES: Composability? Device family specification? Interfaces within families? Interfaces across families? Eventually parts datasheet? Eventually standards?
- Transcriptional device families (RS and CAF) - SynBERC:MIT/Calendar/2006-10-4, SynBERC:MIT/Calendar/2006-10-11
- Post-translational device families (SS) - SynBERC:MIT/Calendar/2007-2-13
- Biosynthetic device families (KJP lab) - SynBERC:MIT/Calendar/2006-10-18, SynBERC:MIT/Calendar/2006-10-25
- Ribozyme device families (AC) - SynBERC:MIT/Calendar/2007-1-10, SynBERC:MIT/Calendar/2007-1-17 and SynBERC:MIT/Calendar/2007-1-24 and SynBERC:MIT/Calendar/2007-3-28
- Translation device families?
- PARTS: SynBERC:MIT/Calendar/2007-2-6
- Terminators
- Coding regions
- RBSs
- Promoters
- Composability and characterization - SynBERC:MIT/Calendar/2006-11-01
- CHASSIS: Why do we want different kinds? What kinds? What are the simplest systems that work?
- Minimal chassis
- Mesoplasma florum - SynBERC:MIT/Calendar/2006-12-13
- E. coli standard strain and rE. coli - SynBERC:MIT/Calendar/2006-12-6
- Yeast
- Power supply - SynBERC:MIT/Calendar/2006-11-15
- Vectors - SynBERC:MIT/Calendar/2007-1-31
- Synthesis technologies
- What is state of the art?
- What are the good ideas?
- How do we get more investment?
- Can the fabs constrain what people synthesize?
- What does the CAD tool look like? - SynBERC:MIT/Calendar/2007-7-18, SynBERC:MIT/Calendar/2007-8-1
- Human practice
- Differentiation and cell to cell communication. Development. Programmed pattern formation. (Arthur Lander, Radhika)
- Standards (also see talk page)
- Load issues
- What demands on the chassis are of most concern to us? Replication, transcription, translation, Enzyme activity?
- Are we regularly placing high demands on the chassis with our existing systems?
- What chassis responses to an applied demand are of relevance? Growth rate, protein synthesis capacity?
- Can we specify a threshold demand level above which the chassis response is so severe as to render the our engineered systems inoperable?
- What demands on the chassis are of most concern to us? Replication, transcription, translation, Enzyme activity?
- Selection against our systems SynBERC:MIT/Calendar/2006-12-20
- e.g. IS elements are showing up in our devices!
- Statistics of codon pairs (UC Irvine folks)
- iGEM 2010 - SynBERC:MIT/Calendar/2006-11-08
- Registry 2.0 - SynBERC:MIT/Calendar/2007-6-20
- Publishing (with CS on Oct 20) - held separately
- Controlled transcriptional termination as an implementation for logic - Chris Anderson
- Designing enzymatic reactions by splitting catalytic activity and substrate specificity potentially by scaffolds - John Dueber? ask Adam Arkin for someone to talk about this
- What is the obvious list of things to do?
- Parts characterization
- How do we get basic tasks done?
- Experience with different parts: RBSs, promoters, terminators - Jen? Chris Anderson? Curt and Hal Alper
- Web of registries - Randy
- Repetitive sequences and potential for recombination - ask Graham Walker, someone in Philadelphia
- Registry of models - Barry and Vincent
- Bacterial counter and how you implement it - Tom or Gerry - SynBERC:MIT/Calendar/2007-5-30
- How do I get a computer inside my cell? - Tom
- Human practices - Michael Rossi
- Writing DNA - Maia, Farren?, Church lab, Adam Arkin, Sasha and polony sequencing - SynBERC:MIT/Calendar/2007-4-3
- Noncoding RNAs - Ron Breaker
- Materials - Angie Belcher, Julie Norville - SynBERC:MIT/Calendar/2007-5-8
- Education in SB - Natalie and Scot and Austin and Michael and Shawn? - SynBERC:MIT/Calendar/2007-3-20, SynBERC:MIT/Calendar/2007-5-22
- Curriculum
- Workshop implementation
- Materials
- Bootcamp
- Security - are we ok with the current investments in biotechnology? - Drew, Gautam? Phil Sharp and Gerry Fink and Jonathan King and Noam Chomsky and Ed Hammond - SynBERC:MIT/Calendar/2007-6-6, SynBERC:MIT/Calendar/2007-6-13
- Must act in the absence of perfect knowledge
- Impact of big pharma and big ag and big energy on our field
- Inteins and Fran Perler from NEB - SynBERC:MIT/Calendar/2007-4-10
- Brian Baynes and Codon Devices - future of DNA synthesis technology
- Ownership, sharing and innovation - SynBERC:MIT/Calendar/2007-5-1, SynBERC:MIT/Calendar/2007-9-26
- IP around DNA fabrication technology (synthesis and automated assembly)
- How do we incent contributions? i.e. documentation of parts in the Registry
- Historical examples around IP
- SynBERC OSI model
- BBF work
- Bioenergy - SynBERC:MIT/Calendar/2007-5-15
- Please add your topic to the list.
Room locations for Spring
Usually 32-D463 except for the following dates
- May 7 - 68-180
- May 28 - no room booked