Stephanopoulos:Production of biochemicals in E. coli

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A major focus of the Stephanopoulos lab is development of E. coli-based biocatalysts.  Target products include antioxidant [[carotenoid]]s such as [[lycopene]] as well as amino acids such as [[tyrosine]], which we are producing with an eye toward [[commodity-polymer]] applications.   
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A major focus of the Stephanopoulos lab is development of ''E. coli''-based biocatalysts.  Target products include antioxidant [[carotenoid]]s such as [[lycopene]] as well as amino acids such as [[tyrosine]], which we are producing with an eye toward [[commodity-polymer]] applications.   
To develop strains, we employ rational, model-based approaches as well as [[Stephanopoulos Lab:Inverse Metabolic Engineering | combinatoric ones]], and have been enthusiastic adopters of the whole-cell stoichiometric models developed by Bernard Palsson and Costas Maranas.
To develop strains, we employ rational, model-based approaches as well as [[Stephanopoulos Lab:Inverse Metabolic Engineering | combinatoric ones]], and have been enthusiastic adopters of the whole-cell stoichiometric models developed by Bernard Palsson and Costas Maranas.

Revision as of 18:10, 12 July 2006

A major focus of the Stephanopoulos lab is development of E. coli-based biocatalysts. Target products include antioxidant carotenoids such as lycopene as well as amino acids such as tyrosine, which we are producing with an eye toward commodity-polymer applications.

To develop strains, we employ rational, model-based approaches as well as combinatoric ones, and have been enthusiastic adopters of the whole-cell stoichiometric models developed by Bernard Palsson and Costas Maranas.

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