Smolke:Tech 21Aug06

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Tech talk references: 21 August 2006 Presenter: Travis Complex target selections Shangguan D, Li Y, Tang Z, Cao ZC, Chen HW, Mallikaratchy P, Sefah K, Yang CJ, and Tan W. Aptamers evolved from live cells as effective molecular probes for cancer study. Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11838-43. DOI:10.1073/pnas.0602615103 | Morris KN, Jensen KB, Julin CM, Weil M, and Gold L. High affinity ligands from in vitro selection: complex targets. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):2902-7. DOI:10.1073/pnas.95.6.2902 | Daniels DA, Chen H, Hicke BJ, Swiderek KM, and Gold L. A tenascin-C aptamer identified by tumor cell SELEX: systematic evolution of ligands by exponential enrichment. Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15416-21. DOI:10.1073/pnas.2136683100 | Aptamer drug/siRNA/qdot conjugates <biblio> tech4 pmid=16778167 tech5 pmid=16740739 tech6 pmid=16823371 tech7 pmid=16495043 tech8 pmid=15520166