Renhao Li Lab:Publications: Difference between revisions
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==2014== | ==2014== | ||
40. W. Zhangª, W. Dengª, L. Zhou, Y. Xu, W. Yang, X. Liang, Y. Wang, J. D. Kulman, X. F. Zhang*, R. Li* | |||
:Identification of a juxtamembrane mechano-sensitive domain in the platelet mechanosensor glycoprotein Ib-IX-V complex | |||
:'''Blood''' Epub ahead of print, 2014. [http://www.bloodjournal.org/content/early/2014/10/30/blood-2014-07-589507 First Edition] | |||
39. W. Deng, S. Cho, P.-C. Su, B. W. Berger, R. Li | 39. W. Deng, S. Cho, P.-C. Su, B. W. Berger, R. Li | ||
:Membrane-enabled dimerization of the intrinsically disordered cytoplasmic domain of ADAM10 | :Membrane-enabled dimerization of the intrinsically disordered cytoplasmic domain of ADAM10 | ||
:''' | :'''Proc. Natl. Acad. Sci.''' (track II) Epub ahead of print, 2014. [http://www.pnas.org/content/early/2014/10/24/1409354111 Early Edition] | ||
Line 49: | Line 54: | ||
==2012== | ==2012== | ||
30. X. Mo, L. Liu, J. A. Lopez, R. Li | 30. X. Mo, L. Liu, J. A. Lopez, R. Li | ||
:Transmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex. | :Transmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex. | ||
:'''J. Thromb. Haemost.''' 10: 1875-1886, 2012. [http://www.ncbi.nlm.nih.gov/pubmed?term=22759073 Pubmed] | :'''J. Thromb. Haemost.''' 10: 1875-1886, 2012. [http://www.ncbi.nlm.nih.gov/pubmed?term=22759073 Pubmed] | ||
Line 57: | Line 62: | ||
==2011== | ==2011== | ||
29. R. Yan, X. Mo, A. M. Paredes, K. Dai, F. Lanza, M. A. Cruz, R. Li | 29. R. Yan, X. Mo, A. M. Paredes, K. Dai, F. Lanza, M. A. Cruz, R. Li | ||
:Reconstitution of platelet glycoprotein Ib-IX complex in phospholipid bilayer nanodiscs. | :Reconstitution of platelet glycoprotein Ib-IX complex in phospholipid bilayer nanodiscs. | ||
:'''Biochemistry''' 50: 10598-10606, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=22080766 Pubmed] | :'''Biochemistry''' 50: 10598-10606, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=22080766 Pubmed] | ||
28. P. A. | |||
28. P. A. McEwanª, W. Yangª, K. H. Carrª, X. Mo, X. Zheng, R. Li*, J. Emsley* | |||
:Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera. | :Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera. | ||
:'''Blood''' 118: 5292-5301, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=21908432 Pubmed] or [http://bloodjournal.hematologylibrary.org/content/118/19/5292.abstract Blood online] | :'''Blood''' 118: 5292-5301, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=21908432 Pubmed] or [http://bloodjournal.hematologylibrary.org/content/118/19/5292.abstract Blood online] | ||
:''with commentary in Blood 118: 5065-5066'' [http://bloodjournal.hematologylibrary.org/content/118/19/5065.full Blood online] | :''with commentary in Blood 118: 5065-5066'' [http://bloodjournal.hematologylibrary.org/content/118/19/5065.full Blood online] | ||
27. W. Deng, S. Srinivasan, X. Zheng, J. A. Putkey, R. Li | |||
27. W. Deng, S. Srinivasan, X. Zheng, J. A. Putkey, R. Li | |||
:Interaction of calmodulin with L-selectin at the membrane interface: implication on the regulation of L-selectin shedding. | :Interaction of calmodulin with L-selectin at the membrane interface: implication on the regulation of L-selectin shedding. | ||
:'''J. Mol. Biol.''' 411: 220-233, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=21664913 Pubmed] | :'''J. Mol. Biol.''' 411: 220-233, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=21664913 Pubmed] | ||
26. S. | |||
26. S. Srinivasanª, W. Dengª, R. Li | |||
:L-selectin transmembrane and cytoplasmic domains are monomeric in membranes. | :L-selectin transmembrane and cytoplasmic domains are monomeric in membranes. | ||
:'''Biochim. Biophys. Acta''' 1808: 1709-1715, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=21316337 Pubmed] | :'''Biochim. Biophys. Acta''' 1808: 1709-1715, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=21316337 Pubmed] | ||
25. Z. Zhou, H.-C. Yeh, H. Jing, C. Wang, Z. Tao, H. Choi, K. Aboulfatova, R. Li, J.-F. Dong | |||
25. Z. Zhou, H.-C. Yeh, H. Jing, C. Wang, Z. Tao, H. Choi, K. Aboulfatova, R. Li, J.-F. Dong | |||
:Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability. | :Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability. | ||
:'''Thromb. Haemost.''' 105: 21-30, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=20886194 Pubmed] | :'''Thromb. Haemost.''' 105: 21-30, 2011. [http://www.ncbi.nlm.nih.gov/pubmed?term=20886194 Pubmed] | ||
==Before 2010== | ==Before 2010== | ||
24. X. Mo, N. X. Nguyen, F.-T. Mu, W. Yang, S.-Z. Luo, H. Fan, R. K. Andrews, M. C. Berndt, R. Li | 24. X. Mo, N. X. Nguyen, F.-T. Mu, W. Yang, S.-Z. Luo, H. Fan, R. K. Andrews, M. C. Berndt, R. Li | ||
:Trans-membrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibα. | :Trans-membrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibα. | ||
:'''J. Biol. Chem.''' 285: 32096-32104, 2010. [http://www.ncbi.nlm.nih.gov/pubmed?term=20716526 Pubmed] | :'''J. Biol. Chem.''' 285: 32096-32104, 2010. [http://www.ncbi.nlm.nih.gov/pubmed?term=20716526 Pubmed] | ||
23. R. Li | |||
23. R. Li | |||
:A hypothesis that explains the heterogeneity of drug-induced immune thrombocytopenia. | :A hypothesis that explains the heterogeneity of drug-induced immune thrombocytopenia. | ||
:'''Blood''' 115: 914, 2010. [http://www.ncbi.nlm.nih.gov/pubmed?term=20110436 Pubmed] | :'''Blood''' 115: 914, 2010. [http://www.ncbi.nlm.nih.gov/pubmed?term=20110436 Pubmed] | ||
22. X. Mo, N. X. Nguyen, P. A. McEwan, X. Zheng, J. A. López, J. Emsley, R. Li | |||
22. X. Mo, N. X. Nguyen, P. A. McEwan, X. Zheng, J. A. López, J. Emsley, R. Li | |||
:Binding of platelet glycoprotein Ibβ through the convex surface of leucine-rich repeats domain of glycoprotein IX. | :Binding of platelet glycoprotein Ibβ through the convex surface of leucine-rich repeats domain of glycoprotein IX. | ||
:'''J. Thromb. Haemost.''' 7: 1533-1540, 2009. [http://www.ncbi.nlm.nih.gov/pubmed?term=19566547 Pubmed] | :'''J. Thromb. Haemost.''' 7: 1533-1540, 2009. [http://www.ncbi.nlm.nih.gov/pubmed?term=19566547 Pubmed] | ||
21. Z. Zhou, H. Jing, Z. Tao, H. Choi, K. Aboulfatova, J. Moake, R. Li, J.-F. Dong | |||
21. Z. Zhou, H. Jing, Z. Tao, H. Choi, K. Aboulfatova, J. Moake, R. Li, J.-F. Dong | |||
:Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13. | :Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13. | ||
:'''Thromb. Res.''' 124: 323-327, 2009. [http://www.ncbi.nlm.nih.gov/pubmed?term=19027144 Pubmed] | :'''Thromb. Res.''' 124: 323-327, 2009. [http://www.ncbi.nlm.nih.gov/pubmed?term=19027144 Pubmed] | ||
20. X. Mo, S.-Z. Luo, J. A. López, R. Li | |||
20. X. Mo, S.-Z. Luo, J. A. López, R. Li | |||
:Juxtamembrane basic residues in the glycoprotein Ibβ cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex. | :Juxtamembrane basic residues in the glycoprotein Ibβ cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex. | ||
:'''FEBS Lett.''' 582: 3270-3274, 2008. [http://www.ncbi.nlm.nih.gov/pubmed?term=18789323 Pubmed] | :'''FEBS Lett.''' 582: 3270-3274, 2008. [http://www.ncbi.nlm.nih.gov/pubmed?term=18789323 Pubmed] | ||
19. S.-Z. Luo, R. Li | |||
19. S.-Z. Luo, R. Li | |||
:Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex. | :Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex. | ||
:'''J. Mol. Biol.''' 382: 448-457, 2008. [http://www.ncbi.nlm.nih.gov/pubmed?term=18674540 Pubmed] | :'''J. Mol. Biol.''' 382: 448-457, 2008. [http://www.ncbi.nlm.nih.gov/pubmed?term=18674540 Pubmed] | ||
18. X. Mo, S.-Z. Luo, A. D. Munday, W. Sun, M. C. Berndt, J. A. López, J.-F. Dong, R. Li | |||
18. X. Mo, S.-Z. Luo, A. D. Munday, W. Sun, M. C. Berndt, J. A. López, J.-F. Dong, R. Li | |||
:The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor. | :The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor. | ||
:'''J. Thromb. Haemost.''' 6: 1789-1795, 2008. [http://www.ncbi.nlm.nih.gov/pubmed?term=18647229 Pubmed] | :'''J. Thromb. Haemost.''' 6: 1789-1795, 2008. [http://www.ncbi.nlm.nih.gov/pubmed?term=18647229 Pubmed] | ||
17. S.-Z. Luo, X. Mo, J. A. López, R. Li | |||
17. S.-Z. Luo, X. Mo, J. A. López, R. Li | |||
:Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex. | :Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex. | ||
:'''J. Thromb. Haemost.''' 5: 2494-2502, 2007. [http://www.ncbi.nlm.nih.gov/pubmed?term=17922811 Pubmed] | :'''J. Thromb. Haemost.''' 5: 2494-2502, 2007. [http://www.ncbi.nlm.nih.gov/pubmed?term=17922811 Pubmed] | ||
16. S.-Z. | |||
16. S.-Z. Luoª, X. Moª, V. Afshar-Kharghan, S. Srinivasan, J. A. López, R. Li | |||
:Glycoprotein Ibα forms disulfide bonds with 2 glycoprotein Ibβ subunits in the resting platelet. | :Glycoprotein Ibα forms disulfide bonds with 2 glycoprotein Ibβ subunits in the resting platelet. | ||
:'''Blood''' 109: 603-609, 2007. [http://www.ncbi.nlm.nih.gov/pubmed?term=17008541 Pubmed] | :'''Blood''' 109: 603-609, 2007. [http://www.ncbi.nlm.nih.gov/pubmed?term=17008541 Pubmed] | ||
:''(with commentary in Blood 109: 393-394)'' | :''(with commentary in Blood 109: 393-394)'' | ||
15. X. Mo, N. Lu, A. Padilla, J. A. López, R. Li | |||
15. X. Mo, N. Lu, A. Padilla, J. A. López, R. Li | |||
:The transmembrane domain of glycoprotein Ibβ is critical to efficient surface expression of glycoprotein Ib-IX complex in the plasma membrane. | :The transmembrane domain of glycoprotein Ibβ is critical to efficient surface expression of glycoprotein Ib-IX complex in the plasma membrane. | ||
:'''J. Biol. Chem.''' 281: 23050-23059, 2006. [http://www.ncbi.nlm.nih.gov/pubmed?term=16757483 Pubmed] | :'''J. Biol. Chem.''' 281: 23050-23059, 2006. [http://www.ncbi.nlm.nih.gov/pubmed?term=16757483 Pubmed] | ||
14. Z. Tao, Y. Peng, L. Nolasco, S. Cal, C. Lopez-Otin, R. Li, J. F. Moake, J. A. López, J.-F. Dong | 14. Z. Tao, Y. Peng, L. Nolasco, S. Cal, C. Lopez-Otin, R. Li, J. F. Moake, J. A. López, J.-F. Dong | ||
Line 128: | Line 147: | ||
:A push-pull mechanism for regulating integrin function. | :A push-pull mechanism for regulating integrin function. | ||
:'''Proc. Natl. Acad. Sci.''' 102: 1424-1429, 2005. | :'''Proc. Natl. Acad. Sci.''' 102: 1424-1429, 2005. | ||
12. R. Li, R. Gorelik, V. Nanda, P. B. Law, J. D. Lear, W. F. DeGrado, J. S. Bennett | 12. R. Li, R. Gorelik, V. Nanda, P. B. Law, J. D. Lear, W. F. DeGrado, J. S. Bennett | ||
:Dimerization of the transmembrane domain of integrin αIIb subunit in cell membranes. | :Dimerization of the transmembrane domain of integrin αIIb subunit in cell membranes. | ||
:'''J. Biol. Chem.''' 279: 26666-26673, 2004. | :'''J. Biol. Chem.''' 279: 26666-26673, 2004. | ||
11. R. Li, J. S. Bennett, W. F. DeGrado | 11. R. Li, J. S. Bennett, W. F. DeGrado | ||
:Structural basis for integrin αIIbβ3 clustering. | :Structural basis for integrin αIIbβ3 clustering. | ||
:'''Biochem. Soc. Trans.''' 32: 412-415, 2004. | :'''Biochem. Soc. Trans.''' 32: 412-415, 2004. | ||
10. R. Li, N. Mitra, H. Gratkowski, G. Vilaire, R. Litvinov, C. Nagasami, J. W. Weisel, J. D. Lear, W. F. DeGrado, J. S. Bennett | 10. R. Li, N. Mitra, H. Gratkowski, G. Vilaire, R. Litvinov, C. Nagasami, J. W. Weisel, J. D. Lear, W. F. DeGrado, J. S. Bennett | ||
Line 141: | Line 163: | ||
:'''Science''' 300: 795-798, 2003. | :'''Science''' 300: 795-798, 2003. | ||
:''(commentary in '''Science''' 300: 755-756)'' | :''(commentary in '''Science''' 300: 755-756)'' | ||
9. R. Li, R. H. Hoess, J. S. Bennett, W. F. DeGrado | 9. R. Li, R. H. Hoess, J. S. Bennett, W. F. DeGrado | ||
:Use of a phage displayed protein scaffold for determining binding specificity to integrins. | :Use of a phage displayed protein scaffold for determining binding specificity to integrins. | ||
:'''Protein Eng.''' 16: 65-72, 2003. | :'''Protein Eng.''' 16: 65-72, 2003. | ||
8. R. Li, C. R. Babu, K. Valentine, J. D. Lear, A. J. Wand, J. S. Bennett, W. F. DeGrado | 8. R. Li, C. R. Babu, K. Valentine, J. D. Lear, A. J. Wand, J. S. Bennett, W. F. DeGrado | ||
:Characterization of the monomeric form of the transmembrane and cytoplasmic domains of integrin β3 subunit by NMR spectroscopy. | :Characterization of the monomeric form of the transmembrane and cytoplasmic domains of integrin β3 subunit by NMR spectroscopy. | ||
:'''Biochemistry''' 41: 15618-15624, 2002. | :'''Biochemistry''' 41: 15618-15624, 2002. | ||
5. R. Li, C. R. Babu, J. D. Lear, A. J. Wand, J. S. Bennett, W. F. DeGrado | 5. R. Li, C. R. Babu, J. D. Lear, A. J. Wand, J. S. Bennett, W. F. DeGrado | ||
Line 158: | Line 183: | ||
:Native-like interactions favored in the unfolded bovine pancreatic trypsin inhibitor have different roles in folding. | :Native-like interactions favored in the unfolded bovine pancreatic trypsin inhibitor have different roles in folding. | ||
:'''Biochemistry''' 41: 2246-2253, 2002. | :'''Biochemistry''' 41: 2246-2253, 2002. | ||
6. J. L. Battiste, R. Li, C. Woodward | 6. J. L. Battiste, R. Li, C. Woodward | ||
:A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility. | :A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility. | ||
:'''Biochemistry''' 41: 2237-2245, 2002. | :'''Biochemistry''' 41: 2237-2245, 2002. | ||
4. K. Akasaka, H. Li, H. Yamada, R. Li, T. Thoresen, C. Woodward | 4. K. Akasaka, H. Li, H. Yamada, R. Li, T. Thoresen, C. Woodward | ||
:Pressure response of protein backbone structure. Pressure-induced amide 15N-chemical shifts in BPTI. | :Pressure response of protein backbone structure. Pressure-induced amide 15N-chemical shifts in BPTI. | ||
:'''Protein Sci.''' 8: 1946-1953, 1999. | :'''Protein Sci.''' 8: 1946-1953, 1999. | ||
3. R. Li, C. Woodward | 3. R. Li, C. Woodward | ||
:The hydrogen exchange core and protein folding. | :The hydrogen exchange core and protein folding. | ||
:'''Protein Sci.''' 8: 1571-1590, 1999. | :'''Protein Sci.''' 8: 1571-1590, 1999. | ||
2. C. Woodward, R. Li | 2. C. Woodward, R. Li | ||
Line 175: | Line 204: | ||
:'''Trends Biochem. Sci.''' 23: 379-381, 1998. | :'''Trends Biochem. Sci.''' 23: 379-381, 1998. | ||
1. J. Ng, R. Li, K. Morgan, J. Simon | |||
1. J. Ng, R. Li, K. Morgan, J. Simon | |||
:Evolutionary conservation and predicted structure of the Drosophila extra sex combs repressor protein. | :Evolutionary conservation and predicted structure of the Drosophila extra sex combs repressor protein. | ||
:'''Mol. Cell. Biol.''' 17: 6663-6672, 1997. | :'''Mol. Cell. Biol.''' 17: 6663-6672, 1997. | ||
(*, corresponding author) | |||
(ª, co-first author; *, co-corresponding author) |
Revision as of 14:26, 30 October 2014
2014
40. W. Zhangª, W. Dengª, L. Zhou, Y. Xu, W. Yang, X. Liang, Y. Wang, J. D. Kulman, X. F. Zhang*, R. Li*
- Identification of a juxtamembrane mechano-sensitive domain in the platelet mechanosensor glycoprotein Ib-IX-V complex
- Blood Epub ahead of print, 2014. First Edition
39. W. Deng, S. Cho, P.-C. Su, B. W. Berger, R. Li
- Membrane-enabled dimerization of the intrinsically disordered cytoplasmic domain of ADAM10
- Proc. Natl. Acad. Sci. (track II) Epub ahead of print, 2014. Early Edition
38. Y. Morioka, C. Casari, N. Wohner, S. Cho, S. Kurata, A. Kitano, O.D. Christophe, P.J. Lenting, R. Li, C.V. Denis, N. Prevost
- Expression of a structurally constrained von Willebrand factor variant triggers acute thrombotic thrombocytopenic purpura in mice.
- Blood 123: 3344-53, 2014. Pubmed
37. L. Zhou, W. Yang, R. Li
- Analysis of inter-subunit contacts reveals the structural malleability of extracellular domains in platelet glycoprotein Ib-IX complex.
- J. Thromb. Haemost. 12: 82-89, 2014. Pubmed
2013
36. A. M. Sevy, J. F. Healey, W. Deng, P. C. Spiegel, S. L. Meeks*, R. Li*
- Epitope mapping of inhibitory antibodies targeting the C2 domain of coagulation factor VIII by hydrogen-deuterium exchange mass spectrometry.
- J. Thromb. Haemost. 11: 2128-2136, 2013 Pubmed
- Made journal cover Gallery
35. X. Liang, S. R. Russell, S. Estelle, L. H. Jones, S. Cho, M. L. Kahn, M. C. Berndt, S. T. Bunting, J. Ware, R. Li
- Specific inhibition of ectodomain shedding of glycoprotein Ibα by targeting its juxtamembrane shedding cleavage site.
- J. Thromb. Haemost. 11: 2155-2162, 2013 Pubmed
34. W. Deng, S. Cho, R. Li
- FERM domain of moesin desorbs the basic-rich cytoplasmic domain of L-selectin from the anionic membrane surface.
- J. Mol. Biol. 425: 3549-3562, 2013 Pubmed
33. P. Mou, Z. Zeng, Q. Li, X. Liu, X. Xin, K. M. Wannemacher, C. Ruan, R. Li, L. F. Brass, L. Zhu
- Identification of a calmodulin-binding domain in Sema4D that regulates its exodomain shedding in platelets.
- Blood 121: 4221-30, 2013 Pubmed
32. W. Deng, J. A. Putkey, R. Li
- Calmodulin adopts an extended conformation when interacting with L-selectin in membranes.
- PLoS ONE 8: e62861, 2013 Pubmed or PLoS ONE online
31. R. Li*, J. Emsley
- The organizing principle of platelet glycoprotein Ib-IX-V complex.
- J. Thromb. Haemost. 11: 605-614, 2013 Pubmed
2012
30. X. Mo, L. Liu, J. A. Lopez, R. Li
- Transmembrane domains are critical to the interaction between platelet glycoprotein V and glycoprotein Ib-IX complex.
- J. Thromb. Haemost. 10: 1875-1886, 2012. Pubmed
- Made journal cover Gallery
2011
29. R. Yan, X. Mo, A. M. Paredes, K. Dai, F. Lanza, M. A. Cruz, R. Li
- Reconstitution of platelet glycoprotein Ib-IX complex in phospholipid bilayer nanodiscs.
- Biochemistry 50: 10598-10606, 2011. Pubmed
28. P. A. McEwanª, W. Yangª, K. H. Carrª, X. Mo, X. Zheng, R. Li*, J. Emsley*
- Quaternary organization of GPIb-IX complex and insights into Bernard-Soulier syndrome revealed by the structures of GPIbβ and a GPIbβ/GPIX chimera.
- Blood 118: 5292-5301, 2011. Pubmed or Blood online
- with commentary in Blood 118: 5065-5066 Blood online
27. W. Deng, S. Srinivasan, X. Zheng, J. A. Putkey, R. Li
- Interaction of calmodulin with L-selectin at the membrane interface: implication on the regulation of L-selectin shedding.
- J. Mol. Biol. 411: 220-233, 2011. Pubmed
26. S. Srinivasanª, W. Dengª, R. Li
- L-selectin transmembrane and cytoplasmic domains are monomeric in membranes.
- Biochim. Biophys. Acta 1808: 1709-1715, 2011. Pubmed
25. Z. Zhou, H.-C. Yeh, H. Jing, C. Wang, Z. Tao, H. Choi, K. Aboulfatova, R. Li, J.-F. Dong
- Cysteine residues in CUB-1 domain are critical for ADAMTS13 secretion and stability.
- Thromb. Haemost. 105: 21-30, 2011. Pubmed
Before 2010
24. X. Mo, N. X. Nguyen, F.-T. Mu, W. Yang, S.-Z. Luo, H. Fan, R. K. Andrews, M. C. Berndt, R. Li
- Trans-membrane and trans-subunit regulation of ectodomain shedding of platelet glycoprotein Ibα.
- J. Biol. Chem. 285: 32096-32104, 2010. Pubmed
23. R. Li
- A hypothesis that explains the heterogeneity of drug-induced immune thrombocytopenia.
- Blood 115: 914, 2010. Pubmed
22. X. Mo, N. X. Nguyen, P. A. McEwan, X. Zheng, J. A. López, J. Emsley, R. Li
- Binding of platelet glycoprotein Ibβ through the convex surface of leucine-rich repeats domain of glycoprotein IX.
- J. Thromb. Haemost. 7: 1533-1540, 2009. Pubmed
21. Z. Zhou, H. Jing, Z. Tao, H. Choi, K. Aboulfatova, J. Moake, R. Li, J.-F. Dong
- Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13.
- Thromb. Res. 124: 323-327, 2009. Pubmed
20. X. Mo, S.-Z. Luo, J. A. López, R. Li
- Juxtamembrane basic residues in the glycoprotein Ibβ cytoplasmic domain are required for assembly and surface expression of glycoprotein Ib-IX complex.
- FEBS Lett. 582: 3270-3274, 2008. Pubmed
19. S.-Z. Luo, R. Li
- Specific heteromeric association of four transmembrane peptides derived from platelet glycoprotein Ib-IX complex.
- J. Mol. Biol. 382: 448-457, 2008. Pubmed
18. X. Mo, S.-Z. Luo, A. D. Munday, W. Sun, M. C. Berndt, J. A. López, J.-F. Dong, R. Li
- The membrane-proximal intermolecular disulfide bonds in glycoprotein Ib influence receptor binding to von Willebrand factor.
- J. Thromb. Haemost. 6: 1789-1795, 2008. Pubmed
17. S.-Z. Luo, X. Mo, J. A. López, R. Li
- Role of the transmembrane domain of glycoprotein IX in assembly of the glycoprotein Ib-IX complex.
- J. Thromb. Haemost. 5: 2494-2502, 2007. Pubmed
16. S.-Z. Luoª, X. Moª, V. Afshar-Kharghan, S. Srinivasan, J. A. López, R. Li
- Glycoprotein Ibα forms disulfide bonds with 2 glycoprotein Ibβ subunits in the resting platelet.
- Blood 109: 603-609, 2007. Pubmed
- (with commentary in Blood 109: 393-394)
15. X. Mo, N. Lu, A. Padilla, J. A. López, R. Li
- The transmembrane domain of glycoprotein Ibβ is critical to efficient surface expression of glycoprotein Ib-IX complex in the plasma membrane.
- J. Biol. Chem. 281: 23050-23059, 2006. Pubmed
14. Z. Tao, Y. Peng, L. Nolasco, S. Cal, C. Lopez-Otin, R. Li, J. F. Moake, J. A. López, J.-F. Dong
- Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.
- Blood 106: 4139-4145, 2005. Pubmed
Postdoctoral Work
13. W. Li, D. G. Metcalf, R. Gorelik, R. Li, N. Mitra, V. Nanda, P. B. Law, J. D. Lear, W. F. DeGrado, J. S. Bennett
- A push-pull mechanism for regulating integrin function.
- Proc. Natl. Acad. Sci. 102: 1424-1429, 2005.
12. R. Li, R. Gorelik, V. Nanda, P. B. Law, J. D. Lear, W. F. DeGrado, J. S. Bennett
- Dimerization of the transmembrane domain of integrin αIIb subunit in cell membranes.
- J. Biol. Chem. 279: 26666-26673, 2004.
11. R. Li, J. S. Bennett, W. F. DeGrado
- Structural basis for integrin αIIbβ3 clustering.
- Biochem. Soc. Trans. 32: 412-415, 2004.
10. R. Li, N. Mitra, H. Gratkowski, G. Vilaire, R. Litvinov, C. Nagasami, J. W. Weisel, J. D. Lear, W. F. DeGrado, J. S. Bennett
- Activation of integrin αIIbβ3 by modulation of transmembrane helix associations.
- Science 300: 795-798, 2003.
- (commentary in Science 300: 755-756)
9. R. Li, R. H. Hoess, J. S. Bennett, W. F. DeGrado
- Use of a phage displayed protein scaffold for determining binding specificity to integrins.
- Protein Eng. 16: 65-72, 2003.
8. R. Li, C. R. Babu, K. Valentine, J. D. Lear, A. J. Wand, J. S. Bennett, W. F. DeGrado
- Characterization of the monomeric form of the transmembrane and cytoplasmic domains of integrin β3 subunit by NMR spectroscopy.
- Biochemistry 41: 15618-15624, 2002.
5. R. Li, C. R. Babu, J. D. Lear, A. J. Wand, J. S. Bennett, W. F. DeGrado
- Oligomerization of the integrin αIIbβ3: roles of the transmembrane and cytoplasmic domains.
- Proc. Natl. Acad. Sci. 98: 12462-12467, 2001.
Graduate Work
7. R. Li, J. L. Battiste, C. Woodward
- Native-like interactions favored in the unfolded bovine pancreatic trypsin inhibitor have different roles in folding.
- Biochemistry 41: 2246-2253, 2002.
6. J. L. Battiste, R. Li, C. Woodward
- A highly destabilizing mutation, G37A, of the bovine pancreatic trypsin inhibitor retains the average native conformation but greatly increases local flexibility.
- Biochemistry 41: 2237-2245, 2002.
4. K. Akasaka, H. Li, H. Yamada, R. Li, T. Thoresen, C. Woodward
- Pressure response of protein backbone structure. Pressure-induced amide 15N-chemical shifts in BPTI.
- Protein Sci. 8: 1946-1953, 1999.
3. R. Li, C. Woodward
- The hydrogen exchange core and protein folding.
- Protein Sci. 8: 1571-1590, 1999.
2. C. Woodward, R. Li
- The slow-exchange core and protein folding.
- Trends Biochem. Sci. 23: 379-381, 1998.
1. J. Ng, R. Li, K. Morgan, J. Simon
- Evolutionary conservation and predicted structure of the Drosophila extra sex combs repressor protein.
- Mol. Cell. Biol. 17: 6663-6672, 1997.
(ª, co-first author; *, co-corresponding author)