Renhao Li Lab

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Welcome to Renhao Li Lab We are interested in membrane proteins and receptors because they are one of the frontiers in protein research and because they are often drug targets that are closely associated with diseases. Our research centers around the following questions: How do membrane receptors transmit signals across the cell membrane? How do certain function or malfunction of membrane receptors lead to diseases? How are these functions regulated by intracellular and extracellular signals? How can we modulate membrane receptors to combat diseases? We focus on membrane receptors involved in cardiovascular and immune diseases. We take a multidisciplinary approach, using a wide array of techniques in molecular biology, structural biology, cell biology, and bioengineering. For details on the ongoing research projects in the lab, please see Research. We are located on the 4th floor of Emory Children's Center, Aflac Cancer Center and Blood Disorders Service, Emory University School of Medicine. See Contact for details.

Recent Updates 3/2016: Congrats to Ed on his successful NIH NRSA predoctoral fellowship application! 2/2016: Renhao gave a symposia talk on Mechanism and Functions of Platelet Mechanosensing at the 2016 Biophysical Society Annual Meeting. 11/2015: Xin and Anum's paper is published in JTH! By disproving the prevalent model of GPIb signaling, this paper re-opens the question with an implication on platelet clearance. 11/2015: Renhao gave an invited talk on "Mechanosensory domain in the platelet shear-receptor, GPIb-IX" at the 2015 AHA Scientific Sessions. 10/2015: Congrats to Wei on the appointment to Instructor! 9/2015: Sam and Yingchun are joining the lab. Welcome! 6/2015: Xin is leaving the lab for an Instructor position. Good luck and best wishes! We will miss you. 5/2015: Renhao gave a talk on GPIb-IX at the 2015 Gordon Conference on the Cell Biology of Platelets and Megakaryocytes. 5/2015: Ed Quach joins up after his rotation in the lab. Welcome, Ed! 1/2015: Wei's Blood paper came out, and it came out with a commentary!