Renhao Li Lab: Difference between revisions

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==Welcome to Renhao Li Lab==
==Welcome to Renhao Li Lab==


We are a lab interested in transmembrane proteins and receptors because they are one of the frontiers in protein research and because they are often drug targets that are closely associated with diseases. Our research centers around the following questions:  
We are interested in membrane proteins and receptors because they are one of the frontiers in protein research and because they are often drug targets that are closely associated with diseases. Our research centers around the following questions:  


*How do membrane receptors transmit signals across the cell membrane?
*How do membrane receptors transmit signals across the cell membrane?
*How can we modulate the transmission of these signals to combat diseases?
*How do certain function or malfunction of membrane receptors lead to diseases? How are these functions regulated by intracellular and extracellular signals?
*How can we modulate membrane receptors to combat diseases?


We focus on membrane receptors involved in cardiovascular and immune diseases.  We take a multidisciplinary approach, using a wide array of techniques in molecular biology, structural biology, cell biology, and bioengineering. For details on the ongoing research projects in the lab, please see [http://openwetware.org/wiki/Renhao_Li_Lab:Research Research].
We focus on membrane receptors involved in cardiovascular and immune diseases.  We take a multidisciplinary approach, using a wide array of techniques in molecular biology, structural biology, cell biology, and bioengineering. For details on the ongoing research projects in the lab, please see [http://openwetware.org/wiki/Renhao_Li_Lab:Research Research].
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==Recent Updates==
==Recent Updates==
*11/2011: Our paper showing, for the first time, a 3-dimensional structural model of the GPIb-IX complex is out in [http://bloodjournal.hematologylibrary.org/content/118/19/5292.abstract Blood]! This model captures everything we know about the GPIb-IX complex, and also raises a number of interesting questions. It is published with a companion [http://bloodjournal.hematologylibrary.org/content/118/19/5065.full commentary] on Blood.
*1/2015: Wei's Blood paper came out, and it came out with a commentary!
*11/2011: Dr. Liang Zhou joined the lab as a postdoc fellow. Mr. Sung Yun Cho joined the lab as a technician.
*12/2014: Ken started his lab rotation in the lab. Welcome, Ken!
*8/2011: We completed the move from [http://www.uth.tmc.edu/bmb/faculty/renhao-li.html UTHealth] to [http://www.pedsresearch.org/research-faculty/profile/renhao-li Emory]. Go to [http://openwetware.org/wiki/Renhao_Li_Lab:Gallery#Group_photos Gallery] for details.
*11/2014: Wei's paper was just accepted by Blood! This is very much a group effort. Thanks everyone!
 
*10/2014: Wei and Sungyun's paper on ADAM10 cytoplasmic domain was just accepted by PNAS!
*2/2014: Peng joins the lab as a visiting student. Welcome, Peng!
*10/2013: 3 papers in one month! Xin, Alex and Liang each has published a first-author paper in J. Thromb. Haemost.
*8/2013: To send Alex off to graduate school, the lab went to the Buford Dam Park for a BBQ picnic!
*7/2013: Lydia started her summer lab rotation in the lab. Welcome, Lydia!
*6/2013: Wei's 2nd paper in 2013, which demonstrates a sequential binding mechanism of moesin and calmodulin to L-selectin in membranes, was just accepted by J. Mol. Biol. Sungyun was the second author on the paper! Congrats, Wei and Sungyun!
*6/2013: Anum joins the lab as a research specialist. Welcome, Anum!


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Revision as of 14:53, 15 January 2015

Home        Research        Publications        Protocols        Lab Members        Gallery       


Welcome to Renhao Li Lab

We are interested in membrane proteins and receptors because they are one of the frontiers in protein research and because they are often drug targets that are closely associated with diseases. Our research centers around the following questions:

  • How do membrane receptors transmit signals across the cell membrane?
  • How do certain function or malfunction of membrane receptors lead to diseases? How are these functions regulated by intracellular and extracellular signals?
  • How can we modulate membrane receptors to combat diseases?

We focus on membrane receptors involved in cardiovascular and immune diseases. We take a multidisciplinary approach, using a wide array of techniques in molecular biology, structural biology, cell biology, and bioengineering. For details on the ongoing research projects in the lab, please see Research.


We are located on the 4th floor of Emory Children's Center, Aflac Cancer Center and Blood Disorders Service, Emory University School of Medicine. See Contact for details.

Recent Updates

  • 1/2015: Wei's Blood paper came out, and it came out with a commentary!
  • 12/2014: Ken started his lab rotation in the lab. Welcome, Ken!
  • 11/2014: Wei's paper was just accepted by Blood! This is very much a group effort. Thanks everyone!
  • 10/2014: Wei and Sungyun's paper on ADAM10 cytoplasmic domain was just accepted by PNAS!
  • 2/2014: Peng joins the lab as a visiting student. Welcome, Peng!
  • 10/2013: 3 papers in one month! Xin, Alex and Liang each has published a first-author paper in J. Thromb. Haemost.
  • 8/2013: To send Alex off to graduate school, the lab went to the Buford Dam Park for a BBQ picnic!
  • 7/2013: Lydia started her summer lab rotation in the lab. Welcome, Lydia!
  • 6/2013: Wei's 2nd paper in 2013, which demonstrates a sequential binding mechanism of moesin and calmodulin to L-selectin in membranes, was just accepted by J. Mol. Biol. Sungyun was the second author on the paper! Congrats, Wei and Sungyun!
  • 6/2013: Anum joins the lab as a research specialist. Welcome, Anum!
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