RenhaoLiLab: Difference between revisions

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==Welcome to Renhao Li Lab==
==Welcome to Renhao Li Lab==


We are a lab interested in transmembrane proteins and receptors because they are one of the frontiers in protein research and because they are often drug targets that are closely associated with diseases. Our research centers around the following questions:  
We are interested in membrane proteins and receptors because they are one of the frontiers in protein research and because they are often drug targets that are closely associated with diseases. Our research centers around the following questions:  


*How do membrane receptors transmit signals across the cell membrane?
*How do membrane receptors transmit signals across the cell membrane?
*How can we modulate the transmission of these signals to combat diseases?
*How do certain function or malfunction of membrane receptors lead to diseases? How are these functions regulated by intracellular and extracellular signals?
*How can we modulate membrane receptors to combat diseases?


We focus on membrane receptors involved in cardiovascular and immune diseases.  We take a multidisciplinary approach, using a wide array of techniques in molecular biology, structural biology, cell biology, and bioengineering. For details on the ongoing research projects in the lab, please see [http://openwetware.org/wiki/Renhao_Li_Lab:Research Research].
We focus on membrane receptors involved in cardiovascular and immune diseases.  We take a multidisciplinary approach, using a wide array of techniques in molecular biology, structural biology, cell biology, and bioengineering. For details on the ongoing research projects in the lab, please see [http://openwetware.org/wiki/Renhao_Li_Lab:Research Research].
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==Recent Updates==
==Recent Updates==
*11/2011: Our paper showing, for the first time, a 3-dimensional structural model of the GPIb-IX complex is out in [http://bloodjournal.hematologylibrary.org/content/118/19/5292.abstract Blood]! This model captures everything we know about the GPIb-IX complex, and also raises a number of interesting questions. It is published with a companion [http://bloodjournal.hematologylibrary.org/content/118/19/5065.full commentary] on Blood.
*12/2011: Rong's paper showing the reconstitution of GPIb-IX complex into Nanodiscs is published in [http://pubs.acs.org/doi/abs/10.1021/bi201351d Biochemistry]. It was one of the papers featured on the journal web site.
*11/2011: Wenjun's paper showing, for the first time, a 3-dimensional structural model of the GPIb-IX complex is out in [http://bloodjournal.hematologylibrary.org/content/118/19/5292.abstract Blood]! This model captures everything we know about the GPIb-IX complex, and also raises a number of interesting questions. It is published with a companion [http://bloodjournal.hematologylibrary.org/content/118/19/5065.full commentary] on Blood.
*11/2011: Dr. Liang Zhou joined the lab as a postdoc fellow. Mr. Sung Yun Cho joined the lab as a technician.
*11/2011: Dr. Liang Zhou joined the lab as a postdoc fellow. Mr. Sung Yun Cho joined the lab as a technician.
*8/2011: We completed the move from [http://www.uth.tmc.edu/bmb/faculty/renhao-li.html UTHealth] to [http://www.pedsresearch.org/research-faculty/profile/renhao-li Emory]. Go to [http://openwetware.org/wiki/Renhao_Li_Lab:Gallery#Group_photos Gallery] for details.
*8/2011: We completed the move from [http://www.uth.tmc.edu/bmb/faculty/renhao-li.html UTHealth] to [http://www.pedsresearch.org/research-faculty/profile/renhao-li Emory]. Go to [http://openwetware.org/wiki/Renhao_Li_Lab:Gallery#Group_photos Gallery] for some snapshots.




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Revision as of 13:25, 31 December 2011

Home        Research        Publications        Protocols        Lab Members        Gallery       


Recent Updates

  • 12/2011: Rong's paper showing the reconstitution of GPIb-IX complex into Nanodiscs is published in Biochemistry. It was one of the papers featured on the journal web site.
  • 11/2011: Wenjun's paper showing, for the first time, a 3-dimensional structural model of the GPIb-IX complex is out in Blood! This model captures everything we know about the GPIb-IX complex, and also raises a number of interesting questions. It is published with a companion commentary on Blood.
  • 11/2011: Dr. Liang Zhou joined the lab as a postdoc fellow. Mr. Sung Yun Cho joined the lab as a technician.
  • 8/2011: We completed the move from UTHealth to Emory. Go to Gallery for some snapshots.