Rebuilding T7 - Revision history

Amallet: /* T7 Family */

2006-06-19T20:04:00Z

T7 Family

←Older revision		Revision as of 20:04, 19 June 2006
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	A more distant relative is the marine phage Roseophage SIO1. See [http://aslo.org/lo/toc/vol_45/issue_2/0408.pdf "The complete genomic sequence of the marine phage Roseophage SIO1 shares homology with nonmarine phages"].		A more distant relative is the marine phage Roseophage SIO1. See [http://aslo.org/lo/toc/vol_45/issue_2/0408.pdf "The complete genomic sequence of the marine phage Roseophage SIO1 shares homology with nonmarine phages"].

-	[~~Data taken from~~ Ian Molineux's chapter in Calendar's "The Bacteriophages" book.]	+	[Based on Ian Molineux's chapter in Calendar's "The Bacteriophages" book.]

	==Publications==		==Publications==

Amallet: /* T7 Family */

2006-06-19T20:03:42Z

T7 Family

←Older revision		Revision as of 20:03, 19 June 2006
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	A more distant relative is the marine phage Roseophage SIO1. See [http://aslo.org/lo/toc/vol_45/issue_2/0408.pdf "The complete genomic sequence of the marine phage Roseophage SIO1 shares homology with nonmarine phages"].		A more distant relative is the marine phage Roseophage SIO1. See [http://aslo.org/lo/toc/vol_45/issue_2/0408.pdf "The complete genomic sequence of the marine phage Roseophage SIO1 shares homology with nonmarine phages"].
		+
		+	[Data taken from Ian Molineux's chapter in Calendar's "The Bacteriophages" book.]

	==Publications==		==Publications==

Amallet at 17:16, 19 June 2006

2006-06-19T17:16:22Z

←Older revision		Revision as of 17:16, 19 June 2006
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	<big>'''[[T7.2]]'''</big> -- A more ambitious effort that revisits some of our initial ideas that were tabled in T7.1.		<big>'''[[T7.2]]'''</big> -- A more ambitious effort that revisits some of our initial ideas that were tabled in T7.1.
		+
		+	== T7 Family ==
		+	The following phages are the ones most closely related to T7. They have a similar genome organization and mainly differ in presence or absence of non-essential genes, many of which are homologous to homing endonucleases or other parasitic elements.
		+	* T3 -- see [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12079351&itool=iconabstr&query_hl=13&itool=pubmed_docsum "Complete nucleotide sequence and likely recombinatorial origin of bacteriophage T3."]
		+	* Yersiniophage φA122 -- see [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12923098&itool=iconpmc&query_hl=11&itool=pubmed_docsum "The genome sequence of Yersinia pestis bacteriophage phiA1122 reveals an intimate history with the coliphage T3 and T7 genomes"]
		+	* Yersiniophage φYe03-12 -- see [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11222590&itool=iconpmc&query_hl=17&itool=pubmed_docsum "Complete genomic sequence of the lytic bacteriophage phiYeO3-12 of Yersinia enterocolitica serotype O:3"]
		+	* Pseudomonas putida phage gh-1 -- see [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12842620&itool=iconabstr&query_hl=8&itool=pubmed_docsum "The complete genomic sequence of lytic bacteriophage gh-1 infecting Pseudomonas putida--evidence for close relationship to the T7 group"]
		+
		+	* [[T7_Feature_Conservation\|Table showing genomic feature conservation]]
		+
		+	A more distant relative is the marine phage Roseophage SIO1. See [http://aslo.org/lo/toc/vol_45/issue_2/0408.pdf "The complete genomic sequence of the marine phage Roseophage SIO1 shares homology with nonmarine phages"].

	==Publications==		==Publications==

Skosuri: /* Summary */

2006-05-31T17:57:39Z

Summary

←Older revision		Revision as of 17:57, 31 May 2006
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	{{Rebuilding T7}}		{{Rebuilding T7}}
	== Summary ==		== Summary ==
-		+	The rebuilding T7 project is an effort to construct a more modelable version of the T7 genome that we can study. These efforts began with our first designs and testing in [[T7.1]], and are now continuing with the [[T7.2]] project.
-	~~Wild-type~~ T7 is a ~~superb organism for discovering the primary components~~ of ~~a biological system [Studier, 1972]~~. ~~However~~, is the ~~original~~ T7 ~~isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?~~	+

	== People ==		== People ==

Skosuri at 01:51, 29 September 2005

2005-09-29T01:51:39Z

←Older revision		Revision as of 01:51, 29 September 2005
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	== Summary ==		== Summary ==

-	Wild-type T7 is a superb organism for discovering the primary components of a biological system ~~{{wikipedia:Ref}}~~ [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?	+	Wild-type T7 is a superb organism for discovering the primary components of a biological system [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?

	== People ==		== People ==

Skosuri at 01:51, 29 September 2005

2005-09-29T01:51:28Z

←Older revision		Revision as of 01:51, 29 September 2005
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	== Summary ==		== Summary ==

-	Wild-type T7 is a superb organism for discovering the primary components of a biological system {{w:Ref~~\|Studier, 1972~~}} [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?	+	Wild-type T7 is a superb organism for discovering the primary components of a biological system {{wikipedia:Ref}} [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?

	== People ==		== People ==

Skosuri at 01:32, 29 September 2005

2005-09-29T01:32:15Z

←Older revision		Revision as of 01:32, 29 September 2005
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	== Summary ==		== Summary ==

-	Wild-type T7 is a superb organism for discovering the primary components of a biological system [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?	+	Wild-type T7 is a superb organism for discovering the primary components of a biological system {{w:Ref\|Studier, 1972}} [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?

	== People ==		== People ==

Skosuri: /* T7 Versions */

2005-09-20T03:49:13Z

T7 Versions

←Older revision		Revision as of 03:49, 20 September 2005
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	== T7 Versions ==		== T7 Versions ==
-	'''[[T7.1]]''' -- Our initial attempt to rebuild the T7 genome.	+	<big>'''[[T7.1]]'''</big> -- Our initial attempt to rebuild the T7 genome.
-	'''[[T7.2]]''' -- A more ambitious effort that revisits some of our initial ideas that were tabled in T7.1.	+
		+	<big>'''[[T7.2]]'''</big> -- A more ambitious effort that revisits some of our initial ideas that were tabled in T7.1.

	==Publications==		==Publications==

Skosuri: /* T7 Versions */

2005-09-20T03:48:22Z

T7 Versions

←Older revision		Revision as of 03:48, 20 September 2005
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	== T7 Versions ==		== T7 Versions ==
-	~~===~~[[T7.1]]~~===~~	+	'''[[T7.1]]''' -- Our initial attempt to rebuild the T7 genome.
-	~~===~~[[T7.2]]~~===~~	+	'''[[T7.2]]''' -- A more ambitious effort that revisits some of our initial ideas that were tabled in T7.1.

	==Publications==		==Publications==

Skosuri at 03:45, 20 September 2005

2005-09-20T03:45:43Z

←Older revision		Revision as of 03:45, 20 September 2005
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	Wild-type T7 is a superb organism for discovering the primary components of a biological system [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?		Wild-type T7 is a superb organism for discovering the primary components of a biological system [Studier, 1972]. However, is the original T7 isolate also best suited for understanding how all parts of the phage are organized to encode a functioning whole?
		+
		+	== People ==
		+	[[Leon Chan]], [[Drew Endy]], [[Sriram Kosuri]]

	==Motivations==		==Motivations==
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	===[[T7.2]]===		===[[T7.2]]===

-	== ~~People~~ ==	+	==Publications==
-	[[Leon Chan]], [[Sriram Kosuri]], [[Drew Endy]]	+	'''Refactoring bacteriophage T7'''<br>
		+	''Nature/EMBO Molecular Systems Biology'' 13 September 2005 DOI:10.1038/msb4100025<br>
		+	[[Leon Chan\|Leon Y. Chan]], [[Sriram Kosuri]] and [[Drew Endy]]<br>
		+	[http://www.nature.com/msb/journal/v1/n1/full/msb4100025.html URL]
		+	[http://openwetware.mit.edu/images/e/ef/Msb4100025.pdf PDF reprint]
		+	[http://www.nature.com/msb/journal/v1/n1/full/msb4100028.html News & Views]
		+	[https://dspace.mit.edu/handle/1721.1/27501 October 2004 version]