Quint Lab:Research - Revision history

Marcel Quint: /* evo devo */

Marcel Quint — Wed, 13 Feb 2013 22:53:16 GMT

evo devo

←Older revision		Revision as of 22:53, 13 February 2013
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	===evo devo===		===evo devo===
	[[Image:Hourglass_mosaic.jpg\|100px\|right]]		[[Image:Hourglass_mosaic.jpg\|100px\|right]]
-	for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis ( see quint et al., [http://www.ncbi.nlm.nih.gov/pubmed/22951968 ''nature 2012'']), we are able to trace the evolutionary path across a complete developmental process.	+	for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al., [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis ( see quint et al., [http://www.ncbi.nlm.nih.gov/pubmed/22951968 ''nature 2012'']), we are able to trace the evolutionary path across a complete developmental process.
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Marcel Quint: /* evo-devo */

Marcel Quint — Wed, 13 Feb 2013 22:52:35 GMT

evo-devo

←Older revision		Revision as of 22:52, 13 February 2013
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-	===evo-devo===	+	===evo devo===
	[[Image:Hourglass_mosaic.jpg\|100px\|right]]		[[Image:Hourglass_mosaic.jpg\|100px\|right]]
	for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis ( see quint et al., [http://www.ncbi.nlm.nih.gov/pubmed/22951968 ''nature 2012'']), we are able to trace the evolutionary path across a complete developmental process.		for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis ( see quint et al., [http://www.ncbi.nlm.nih.gov/pubmed/22951968 ''nature 2012'']), we are able to trace the evolutionary path across a complete developmental process.
	\|}		\|}

Marcel Quint: /* evo-devo */

Marcel Quint — Wed, 13 Feb 2013 22:52:10 GMT

evo-devo

←Older revision		Revision as of 22:52, 13 February 2013
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	===evo-devo===		===evo-devo===
	[[Image:Hourglass_mosaic.jpg\|100px\|right]]		[[Image:Hourglass_mosaic.jpg\|100px\|right]]
-	for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis, we are able to trace the evolutionary path across a complete developmental process.	+	for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis ( see quint et al., [http://www.ncbi.nlm.nih.gov/pubmed/22951968 ''nature 2012'']), we are able to trace the evolutionary path across a complete developmental process.
	\|}		\|}

Marcel Quint at 22:49, 13 February 2013

Marcel Quint — Wed, 13 Feb 2013 22:49:06 GMT

←Older revision		Revision as of 22:49, 13 February 2013
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	our lab is primarily interested in understanding the genetics and molecular biology of [http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana] and related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae]. phytohormones are one of the classic fields in [http://en.wikipedia.org/wiki/Plant_physiology plant physiology] and the past has shown that understanding hormone action in plants bears great potential for agricultural and horticultural applications. by contributing to the current state of knowledge of hormone biology we hope to participate in the advancement of [http://en.wikipedia.org/wiki/Crop_science crop science].		our lab is primarily interested in understanding the genetics and molecular biology of [http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana] and related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae]. phytohormones are one of the classic fields in [http://en.wikipedia.org/wiki/Plant_physiology plant physiology] and the past has shown that understanding hormone action in plants bears great potential for agricultural and horticultural applications. by contributing to the current state of knowledge of hormone biology we hope to participate in the advancement of [http://en.wikipedia.org/wiki/Crop_science crop science].

-	Secondly, we are fascinated by the mechanisms of [http://en.wikipedia.org/wiki/Molecular_evolution molecular evolution] and how they shape plant growth and development. That ranges from learning about the evolutionary history of signaling genes to phylotranscriptomic approaches to plant [http://en.wikipedia.org/wiki/Evo_devoevo devo ~~research~~].	+	Secondly, we are fascinated by the mechanisms of [http://en.wikipedia.org/wiki/Molecular_evolution molecular evolution] and how they shape plant growth and development. That ranges from learning about the evolutionary history of signaling genes to phylotranscriptomic approaches to plant [http://en.wikipedia.org/wiki/Evo_devoevo evo devo] research.
	<br>		<br>
	we apply mostly [http://en.wikipedia.org/wiki/Genomics genomics] approaches, such as:		we apply mostly [http://en.wikipedia.org/wiki/Genomics genomics] approaches, such as:

Marcel Quint at 22:48, 13 February 2013

Marcel Quint — Wed, 13 Feb 2013 22:48:24 GMT

←Older revision		Revision as of 22:48, 13 February 2013
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	our lab is primarily interested in understanding the genetics and molecular biology of [http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana] and related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae]. phytohormones are one of the classic fields in [http://en.wikipedia.org/wiki/Plant_physiology plant physiology] and the past has shown that understanding hormone action in plants bears great potential for agricultural and horticultural applications. by contributing to the current state of knowledge of hormone biology we hope to participate in the advancement of [http://en.wikipedia.org/wiki/Crop_science crop science].		our lab is primarily interested in understanding the genetics and molecular biology of [http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana] and related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae]. phytohormones are one of the classic fields in [http://en.wikipedia.org/wiki/Plant_physiology plant physiology] and the past has shown that understanding hormone action in plants bears great potential for agricultural and horticultural applications. by contributing to the current state of knowledge of hormone biology we hope to participate in the advancement of [http://en.wikipedia.org/wiki/Crop_science crop science].

-	Secondly, we are fascinated by the mechanisms of [http://en.wikipedia.org/wiki/Molecular_evolution molecular evolution] and how they shape plant ~~life~~. ~~Learning~~ about the evolutionary history of signaling ~~pathways may help~~ to ~~further our understanding of important developmental processes regulated by these signaling cascades~~.	+	Secondly, we are fascinated by the mechanisms of [http://en.wikipedia.org/wiki/Molecular_evolution molecular evolution] and how they shape plant growth and development. That ranges from learning about the evolutionary history of signaling genes to phylotranscriptomic approaches to plant [http://en.wikipedia.org/wiki/Evo_devoevo devo research].
	<br>		<br>
	we apply mostly [http://en.wikipedia.org/wiki/Genomics genomics] approaches, such as:		we apply mostly [http://en.wikipedia.org/wiki/Genomics genomics] approaches, such as:

Marcel Quint at 22:46, 13 February 2013

Marcel Quint — Wed, 13 Feb 2013 22:46:01 GMT

←Older revision		Revision as of 22:46, 13 February 2013
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	*whole genome [http://en.wikipedia.org/wiki/Expression_profiling expression profiling]		*whole genome [http://en.wikipedia.org/wiki/Expression_profiling expression profiling]
	*utilizing natural [http://en.wikipedia.org/wiki/Genetic_variation genetic variation] within the global arabidopsis gene pool		*utilizing natural [http://en.wikipedia.org/wiki/Genetic_variation genetic variation] within the global arabidopsis gene pool
-	*[http://en.wikipedia.org/wiki/Quantitative_genetics quantitative genetics] → [http://en.wikipedia.org/wiki/~~Quantitative_trait_locus qtl~~] ~~mapping~~	+	*[http://en.wikipedia.org/wiki/Quantitative_genetics quantitative genetics]
-	*evolutionary and [http://en.wikipedia.org/wiki/~~Population_genomics population genomics~~]	+	*[http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Molecular_evolution molecular evolution]
	*[http://en.wikipedia.org/wiki/Comparative_genomics comparative genomics]<br>		*[http://en.wikipedia.org/wiki/Comparative_genomics comparative genomics]<br>

Marcel Quint at 22:42, 13 February 2013

Marcel Quint — Wed, 13 Feb 2013 22:42:46 GMT

←Older revision		Revision as of 22:42, 13 February 2013
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	[[Image:Homepic.jpg‎\|260px\|right]]		[[Image:Homepic.jpg‎\|260px\|right]]
	<h3><font style="color:#F8B603;">broad research scope</font></h3>		<h3><font style="color:#F8B603;">broad research scope</font></h3>
-	'''HOW''' do organisms adapt to the environment and how do they react to different ~~biotic~~ and ~~abiotic~~ stimuli? <br>	+	'''HOW''' do organisms adapt to the environment and how do they react to different internal and external stimuli? <br>
	major players in the conversion of such stimuli into cellular responses are hormones acting as signaling molecules.		major players in the conversion of such stimuli into cellular responses are hormones acting as signaling molecules.
	our lab is primarily interested in understanding the genetics and molecular biology of [http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana] and related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae]. phytohormones are one of the classic fields in [http://en.wikipedia.org/wiki/Plant_physiology plant physiology] and the past has shown that understanding hormone action in plants bears great potential for agricultural and horticultural applications. by contributing to the current state of knowledge of hormone biology we hope to participate in the advancement of [http://en.wikipedia.org/wiki/Crop_science crop science].		our lab is primarily interested in understanding the genetics and molecular biology of [http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana] and related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae]. phytohormones are one of the classic fields in [http://en.wikipedia.org/wiki/Plant_physiology plant physiology] and the past has shown that understanding hormone action in plants bears great potential for agricultural and horticultural applications. by contributing to the current state of knowledge of hormone biology we hope to participate in the advancement of [http://en.wikipedia.org/wiki/Crop_science crop science].

Marcel Quint at 07:34, 6 December 2012

Marcel Quint — Thu, 06 Dec 2012 07:34:59 GMT

←Older revision		Revision as of 07:34, 6 December 2012
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	{{Template:Quint Lab}}		{{Template:Quint Lab}}
		+	{\| cellspacing="2px" cellpadding="0" border="0" style="padding: 0px; width: 790px; color: #000000; background-color: #ffffff;"
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		+	<h3><font style="color:#F8B603;">let's play</font></h3>
		+	"real science has the potential to not only amaze, but also transform the way one thinks of the world and oneself. this is because the process of science is little different from the deeply resonant, natural processes of play. play enables humans (and other mammals) to discover (and create) relationships and patterns. when one adds rules to play, a game is created. this is science: the process of playing with rules that enables one to reveal previously unseen patterns of relationships that extend our collective understanding of nature." - [http://rsbl.royalsocietypublishing.org/content/7/2/168.long Blackawton et al., 2011, Biology letters]
		+	\|}
		+
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Marcel Quint at 13:33, 22 August 2012

Marcel Quint — Wed, 22 Aug 2012 13:33:33 GMT

←Older revision		Revision as of 13:33, 22 August 2012
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	===evo-devo===		===evo-devo===
		+	[[Image:Hourglass_mosaic.jpg\|100px\|right]]
	for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis, we are able to trace the evolutionary path across a complete developmental process.		for one, we are interested in the evolutionary history of gene families that are involved in important signaling cascades, such as the ubiquitin-proteasome system (see schumann et al. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''plant physiology 2011'']). furthermore, we are developing ways to utilize whole genome transcriptional information for evolutionary approaches in close collaboration with the lab of [http://www.informatik.uni-halle.de/arbeitsgruppen/bioinformatik/mitarbeiterinnen/grosse/?lang=en ivo grosse]. by applying phylotranscriptomics – the combination of [http://en.wikipedia.org/wiki/Phylogenetics phylogenetics] and [http://en.wikipedia.org/wiki/Transcriptomics transcriptomics] – to developmental series such as embryogenesis, we are able to trace the evolutionary path across a complete developmental process.
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Marcel Quint at 10:27, 21 August 2012

Marcel Quint — Tue, 21 Aug 2012 10:27:40 GMT

←Older revision		Revision as of 10:27, 21 August 2012
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	from an evolutionary perspective it will be important to learn about the differences in auxin responses on the physiological and the transcriptional level between species. Comparison of inter-species with intra-species variation may shed new light on the evolutionary development of the auxin response pathway(s). We are using closely related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae] species such as thlaspi arvense in this picture for this type of analysis which - in addition to the evolutionary perspective - is most interesting for possible future knowledge transfer to agronomically important species from that family.		from an evolutionary perspective it will be important to learn about the differences in auxin responses on the physiological and the transcriptional level between species. Comparison of inter-species with intra-species variation may shed new light on the evolutionary development of the auxin response pathway(s). We are using closely related [http://en.wikipedia.org/wiki/Brassicaceae brassicaceae] species such as thlaspi arvense in this picture for this type of analysis which - in addition to the evolutionary perspective - is most interesting for possible future knowledge transfer to agronomically important species from that family.
	\|}		\|}
-

	{\| cellspacing="2px" cellpadding="0" border="0" style="padding: 0px; width: 790px; color: #000000; background-color: #ffffff;"		{\| cellspacing="2px" cellpadding="0" border="0" style="padding: 0px; width: 790px; color: #000000; background-color: #ffffff;"