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'''HOW''' do organisms adapt to the environment and how do they react to different biotic and abiotic stimuli? <br>
[[Image:Arabidopsis_smiley-compressed.jpg‎|400px|left]][[Image:Wordle_03-13.png‎|350px|right]] <br>
major players in the conversion of such stimuli into cellular responses are hormones acting as signaling molecules.
 
our lab is primarily interested in understanding the genetics and molecular biology of
 
[http://en.wikipedia.org/wiki/Auxin auxin] and other [http://en.wikipedia.org/wiki/Plant_hormone plant hormone] responses in the tiny weed [http://en.wikipedia.org/wiki/Arabidopsis_thaliana arabidopsis thaliana]. since several of these hormone-triggered signaling cascades are regulated by the [http://en.wikipedia.org/wiki/Proteasome ubiquitin-proteasome system] SCF-type E3 ubiquitin ligases and functional characterization of their selective f-box protein subunits are another focus of our research activities.<br>
 
we apply mostly genetic approaches, such as:  
 
*forward genetic screens
'''NEWS''' --> the lab is currently moving to the [http://www.uni-halle.de Martin Luther University Halle-Wittenberg] --> new lab website @ [http://quintlab.landw.uni-halle.de/ http://quintlab.landw.uni-halle.de/]
*reverse genetics
 
*utilizing natural variation within the global arabidopsis gene pool
 
*quantitative genetics → [http://en.wikipedia.org/wiki/Quantitative_trait_locus qtl] mapping<br>
 
the quint lab is part of the [http://www.ipb-halle.de/en/research/molecular-signal-processing/ department of molecular signal processing] at the [http://www.ipb-halle.de/en/ leibniz institute of plant biochemistry] in halle (saale), germany. 5 keywords to describe our major [http://openwetware.org/wiki/Quint_Lab:Research research interests]: <br>
- thermomorphogenesis
- [http://en.wikipedia.org/wiki/Auxin auxin]<br>
- [http://en.wikipedia.org/wiki/Genetic_diversity natural variation]<br>
- [http://en.wikipedia.org/wiki/Evo-devo evo-devo]<br>
- [http://en.wikipedia.org/wiki/Genomics genomics]/[http://en.wikipedia.org/wiki/Transcriptomics transcriptomics]<br>
 


we are located at the [http://www.ipb-halle.de/en/ leibniz institute of plant biochemistry] (ipb) in halle. our junior research group is part of a larger research network that deals with structures and mechanisms of biological information processing, the so-called [http://www.exzellenznetzwerk-biowissenschaften.uni-halle.de/component/option,com_frontpage/Itemid,1/ exzellenznetzwerk für biowissenschaften]. see our [http://www.ipb-halle.de/de/forschung/stress-und-entwicklungsbiologie/forschungsgruppen/auxin-signaltransduktion/ static website].
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'''selected publications''':
[[Image:Logo_natplants.png|100px|left]] Quint M, Delker C, Franklin K, Wigge P, Halliday K, van Zanten M ('''2015''') Molecular and genetic control of plant thermomorphogenesis. ''Nature Plants'' (accepted). <br>
[[Image:BioRxiv_logo.png|100px|left]] Ibañez C, Poeschl Y, Peterson T, Bellstädt J, Denk K, Gogol-Döring A, Quint M, Delker C ('''2015''') Developmental plasticity of Arabidopsis thaliana accessions across an ambient temperature range. [http://www.biorxiv.org/content/early/2015/03/30/017285 ''bioRxiv preprint'']  ('''open access'''). <br>
[[Image:Logo_BMCPB.png|100px|left]] Raschke A, Ibañez C, Ullrich KK, Anwer MU, Becker S, Glöckner A, Trenner J, Denk K, Saal B, Sun X, Ni M, Davis SJ, Delker C, Quint M ('''2015''') Natural Variants of ELF3 Affect Thermomorphogenesis by Transcriptionally Modulating PIF4-Dependent Auxin Response Genes. [http://www.biomedcentral.com/1471-2229/15/197 ''BMC Plant Biology 15:197'']  ('''open access'''). <br>
[[Image:MBE_logo.png|100px|left]] Drost H-G, Gabel A, Grosse I, Quint M ('''2015''') Evidence for active maintenance of phylotranscriptomic hourglass patterns in animal and plant embryogenesis. [http://mbe.oxfordjournals.org/content/early/2015/03/05/molbev.msv012.full.pdf+html ''Molecular Biology and Evolution'' 32:1221-1231]. ('''open access''')<br>
[[Image:Cell_reports_logo3.png|100px|left]] Delker C, Sonntag L, Velikkakam James G, Janitza P, Ibañez C, Ziermann, H, Peterson T, Denk K, Mull S, Ziegler J, Davis SJ, Schneeberger K, Quint M ('''2014''') The DET1-COP1-HY5 pathway constitutes a multipurpose signaling module regulating plant photomorphogenesis and thermomorphogenesis. [http://www.cell.com/cell-reports/abstract/S2211-1247%2814%2901009-2# ''Cell Reports'' 9:1983-1989]. ('''open access''')<br>
Degrading new insights into temperature sensing in plants: [http://news.cell.com/cellreports/cell-reports/degrading-new-insights-into-temperature-sensing-in-plants-commentary-by-christine-queitsch Commentary by Christine Queitsch]
[[Image:logo_pone.png|100px|left]] Navarro-Quezada A, Schumann N, Quint M ('''2013''') Plant F-Box protein evolution is determined by lineage-specific timing of major gene family expansion waves. [http://dx.plos.org/10.1371/journal.pone.0068672 ''PloS ONE'' 8:e68672]. ('''open access''') <br>
[[Image:Logo_naturesmall.png|100px|left]] Quint M, Drost H-G, Gabel A, Ullrich KK, Boenn M, Grosse I ('''2012''') A transcriptomic hourglass in plant embryogenesis. [http://www.ncbi.nlm.nih.gov/pubmed/22951968 ''Nature'' 490:98-101]. <br>
[[Media:Nature_cover_10-04-2012.jpg|cover]]; [http://f1000.com/717957827?bd=1 Faculty of 1000 recommended]<br>
[[Image:Logo_trends.png|100px|left]] Delker C, Quint M ('''2011''') Expression level polymorphisms: heritable traits shaping natural variation. [http://www.ncbi.nlm.nih.gov/pubmed/21700486 ''Trends in Plant Science'' 9:481-488].<br>
[[Image:Logo_plantphys.png‎|100px|left]] Schumann N, Navarro-Quezada AR, Ullrich K, Kuhl C, Quint M ('''2011''') Molecular Evolution and Selection Patterns of Plant F-box Proteins with C-terminal Kelch Repeats. [http://www.ncbi.nlm.nih.gov/pubmed/21119043 ''Plant Physiology'' 155:835-850]. ('''open access''')<br>
[[Image:Logo_plant_cell.png|100px|left]] Delker C, Pöschl Y, Raschke A, Ullrich K, Ettingshausen S, Hauptmann V, Grosse I, Quint M ('''2010''') Natural variation of transcriptional auxin response networks in ''Arabidopsis thaliana''. [http://www.ncbi.nlm.nih.gov/pubmed/20622145 ''Plant Cell'' 22:2184-2200]. ('''open access''')<br>
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Latest revision as of 08:15, 16 December 2015

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NEWS --> the lab is currently moving to the Martin Luther University Halle-Wittenberg --> new lab website @ http://quintlab.landw.uni-halle.de/


the quint lab is part of the department of molecular signal processing at the leibniz institute of plant biochemistry in halle (saale), germany. 5 keywords to describe our major research interests:
- thermomorphogenesis - auxin
- natural variation
- evo-devo
- genomics/transcriptomics


selected publications:

Quint M, Delker C, Franklin K, Wigge P, Halliday K, van Zanten M (2015) Molecular and genetic control of plant thermomorphogenesis. Nature Plants (accepted).


Ibañez C, Poeschl Y, Peterson T, Bellstädt J, Denk K, Gogol-Döring A, Quint M, Delker C (2015) Developmental plasticity of Arabidopsis thaliana accessions across an ambient temperature range. bioRxiv preprint (open access).


Raschke A, Ibañez C, Ullrich KK, Anwer MU, Becker S, Glöckner A, Trenner J, Denk K, Saal B, Sun X, Ni M, Davis SJ, Delker C, Quint M (2015) Natural Variants of ELF3 Affect Thermomorphogenesis by Transcriptionally Modulating PIF4-Dependent Auxin Response Genes. BMC Plant Biology 15:197 (open access).


Drost H-G, Gabel A, Grosse I, Quint M (2015) Evidence for active maintenance of phylotranscriptomic hourglass patterns in animal and plant embryogenesis. Molecular Biology and Evolution 32:1221-1231. (open access)


Delker C, Sonntag L, Velikkakam James G, Janitza P, Ibañez C, Ziermann, H, Peterson T, Denk K, Mull S, Ziegler J, Davis SJ, Schneeberger K, Quint M (2014) The DET1-COP1-HY5 pathway constitutes a multipurpose signaling module regulating plant photomorphogenesis and thermomorphogenesis. Cell Reports 9:1983-1989. (open access)

Degrading new insights into temperature sensing in plants: Commentary by Christine Queitsch


Navarro-Quezada A, Schumann N, Quint M (2013) Plant F-Box protein evolution is determined by lineage-specific timing of major gene family expansion waves. PloS ONE 8:e68672. (open access)


Quint M, Drost H-G, Gabel A, Ullrich KK, Boenn M, Grosse I (2012) A transcriptomic hourglass in plant embryogenesis. Nature 490:98-101.

cover; Faculty of 1000 recommended


Delker C, Quint M (2011) Expression level polymorphisms: heritable traits shaping natural variation. Trends in Plant Science 9:481-488.


Schumann N, Navarro-Quezada AR, Ullrich K, Kuhl C, Quint M (2011) Molecular Evolution and Selection Patterns of Plant F-box Proteins with C-terminal Kelch Repeats. Plant Physiology 155:835-850. (open access)


Delker C, Pöschl Y, Raschke A, Ullrich K, Ettingshausen S, Hauptmann V, Grosse I, Quint M (2010) Natural variation of transcriptional auxin response networks in Arabidopsis thaliana. Plant Cell 22:2184-2200. (open access)


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