Purple W/F Research Proposal

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1. Begin to define your research proposal by making a wiki page to collect your ideas and resources (you can do this on one page with your partner or split the effort and each turn in an individual page). Keep in mind that your presentation to the class will ultimately need:
1. Begin to define your research proposal by making a wiki page to collect your ideas and resources (you can do this on one page with your partner or split the effort and each turn in an individual page). Keep in mind that your presentation to the class will ultimately need:
-
-a brief project overview - Mod2 type screening, but with mechanistic properties of cells instead
+
-a brief project overview -> We are looking into implementing a Mod2 type screening, but instead of cell viability measured through flow cytometry, we would screen mechanistic properties. In this way we can see how cells change with time over a full dosing schedule. The other main idea we were looking into is using this as a screening technique for cancer (see below for more details).
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-sufficient background information for everyone to understand your proposal -  Alejandro has most of this.
+
-sufficient background information for everyone to understand your proposal -> Alejandro has most of this.
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We have not yet discussed what we will focus on, one idea is cancer screening. Could this be sensitive enough to pre-screen for metastases?  
+
We have not yet discussed what we will focus on, one idea is cancer screening. Could this technique be sensitive enough to pre-screen for metastases?  
  http://www.rsc.org/images/loc/2012/pdf/4.A1-2.pdf; Example of Screening by mechanistic properties
  http://www.rsc.org/images/loc/2012/pdf/4.A1-2.pdf; Example of Screening by mechanistic properties
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  http://www.sciencedirect.com/science/article/pii/S0006349506724808; Specifically relavent to Leukemia screenings
+
  http://www.sciencedirect.com/science/article/pii/S0006349506724808; Specifically relevant to Leukemia screenings

Revision as of 01:07, 4 December 2013

1. Begin to define your research proposal by making a wiki page to collect your ideas and resources (you can do this on one page with your partner or split the effort and each turn in an individual page). Keep in mind that your presentation to the class will ultimately need:

-a brief project overview -> We are looking into implementing a Mod2 type screening, but instead of cell viability measured through flow cytometry, we would screen mechanistic properties. In this way we can see how cells change with time over a full dosing schedule. The other main idea we were looking into is using this as a screening technique for cancer (see below for more details). -sufficient background information for everyone to understand your proposal -> Alejandro has most of this. We have not yet discussed what we will focus on, one idea is cancer screening. Could this technique be sensitive enough to pre-screen for metastases?

http://www.rsc.org/images/loc/2012/pdf/4.A1-2.pdf; Example of Screening by mechanistic properties
http://www.sciencedirect.com/science/article/pii/S0006349506724808; Specifically relevant to Leukemia screenings


   a statement of the research problem and goals
   project details and methods
   predicted outcomes if everything goes according to plan and if nothing does
   needed resources to complete the work
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