Pefabloc: Difference between revisions
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(New page: ==Purpose== *Pefabloc is the commerzial name for AEBSF (4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride). It is a irreversible serine protease inhibitor and inhibits proteases like...) |
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==Procurement== | ==Procurement== | ||
You can buy Pefabloc for example at [http://www.sigmaaldrich.com/catalog/search/ProductDetail/FLUKA/76307 Sigma]. | *You can buy Pefabloc for example at [http://www.sigmaaldrich.com/catalog/search/ProductDetail/FLUKA/76307 Sigma]. | ||
==Use== | ==Use== | ||
Typical usage is 0.1 - 1.0 mM. | *Typical usage is 0.1 - 1.0 mM. | ||
*To get 100 mM stock dissolve 100 mg in 4.18 ml water. | |||
*To get 250 mM stock dissove 100 mg in 1.67 ml water. | |||
==Safety== | ==Safety== | ||
Pefabloc should be handeld carefully. | *Pefabloc should be handeld carefully. | ||
==Links== | ==Links== | ||
Latest revision as of 06:22, 30 April 2008
Purpose
- Pefabloc is the commerzial name for AEBSF (4-(2-Aminoethyl) benzenesulfonyl fluoride hydrochloride). It is a irreversible serine protease inhibitor and inhibits proteases like chymotrypsin, kallikrein, plasmin, thrombin, and trypsin. The specificity is similar to the inhibitor PMSF, but Pefabloc is more stable, better soluble and less toxic.
- Molecular Weight: 239.69
Procurement
- You can buy Pefabloc for example at Sigma.
Use
- Typical usage is 0.1 - 1.0 mM.
- To get 100 mM stock dissolve 100 mg in 4.18 ml water.
- To get 250 mM stock dissove 100 mg in 1.67 ml water.
Safety
- Pefabloc should be handeld carefully.
