OpenSourceMalaria:Triazolopyrazine Series Mechanism of Action: Difference between revisions
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Some series four compounds have been found to inhibit the PfATP4 ion channel in an assay performed by Kiaran Kirk's lab at Australian National University. This page will be regularly edited to update OSM's understanding of this activity with both series four compounds and other antimalarials currently being pursued by other research groups. | |||
'''PfATP4''' | |||
PfATP4 is the apparent target of a number of different chemotypes: [http://www.sciencedirect.com/science/article/pii/S2211320715300051 Kirk Review] | PfATP4 is the apparent target of a number of different chemotypes: [http://www.sciencedirect.com/science/article/pii/S2211320715300051 Kirk Review] |
Revision as of 21:54, 5 June 2016
Some series four compounds have been found to inhibit the PfATP4 ion channel in an assay performed by Kiaran Kirk's lab at Australian National University. This page will be regularly edited to update OSM's understanding of this activity with both series four compounds and other antimalarials currently being pursued by other research groups.
PfATP4
PfATP4 is the apparent target of a number of different chemotypes: Kirk Review