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{{OpenSourceMalaria}}
{{OpenSourceMalaria}}


General links for resources relevant to open source malaria.<br>
===Outputs of the Open Source Malaria Project===


Open Source Drug Discovery – A Limited Tutorial, M. N. Robertson, P. M. Ylioja, A. E. Williamson, M. Woelfle, M. Robins, K. A. Badiola, P. Willis, P. Olliaro, T. N. C. Wells and M. H. Todd, ''Parasitology'' '''2014''', ''141'', 148-157 [http://dx.doi.org/10.1017/S0031182013001121 Paper] [http://www.altmetric.com/details.php?domain=journals.cambridge.org&citation_id=1717228 Altmetric Data]<br>
[https://www.ebi.ac.uk/chembl/malaria/doc/inspect/CHEMBL2113921 First published project data set]<br>
[https://github.com/OpenSourceMalaria/OSM_compounds Master List of Chemical Compounds made]<br>
===Non-publication/data Outputs===
'''Open Source Drug Discovery for Malaria Conference, Sydney, February 2012''' (Articles about this meeting: [http://sydney.edu.au/news/science/397.html?newscategoryid=63&newsstoryid=8775 1], [http://nsaunders.wordpress.com/2012/05/11/my-day-out-at-osddmalaria/ 2])<br>
*Planning notes: [[OSDDMalaria:OSDD Malaria Meeting Sydney 2012 | OSDD Malaria Meeting Sydney 2012]].<br>
*Meeting Summary, including links to talks, [http://www.thesynapticleap.org/node/390 here].<br>
[http://malaria.ourexperiment.org/data/files/10840/OSM%20Newsletter%20April%202014.pdf April 2014 Newsletter]<br>
[[Short guide to using the Electronic Lab Notebook]]<br>
[https://github.com/OpenSourceMalaria/OSM_To_Do_List/issues/496 May 2017 Flyer made for conference distribution]
===Articles/Features about Open Source Malaria===
[https://youtu.be/hU-4WHeeyss Alice's TedX talk, "Breaking Good"]
[http://dx.doi.org/10.1017/epi.2013.33 Paper] from December 2013 describing OSM, comparing it with other initiatives such as the Bradner lab and containing a discussion of other meta-aspects of open drug discovery<br>
[http://www.mmv.org/newsroom/news/potential-new-class-antimalarials-now-open-source Launch of Series 4]<br>
[http://www.mmv.org/partnering/interviews/drug-discovery-difference MMV interview with Mat Todd about open drug discovery]<br>
[http://www.highlighthealth.org/open-science/open-source-drug-discovery-for-malaria/ Article by Walter Jessen on Highlight Health 2.0]<br>
[http://www.guardian.co.uk/global-development-professionals-network/2013/apr/29/malaria-innovations-top-ten-world-malaria-day Guardian Innovations in Malaria]<br>
[https://blog.cloudcitydevelopment.com/2013/07/23/open-source-the-bio-lab-make-a-difference-in-malaria-research/ Development of the Website]<br>
[http://intermolecular.wordpress.com/2013/07/15/an-example-of-open-source-drug-discovery/ An Example of Open Source Drug Discovery]<br>
[http://www.guardian.co.uk/global-development-professionals-network/2013/jul/24/open-source-drug-discovery-research Feature in the Guardian about open source drug discovery for malaria] with [http://www.theguardian.com/global-development-professionals-network/2013/aug/14/letters-should-molecules-be-patented separate discussion] of the terminology "open source" when referring to drug discovery.<br>
[http://www.flickr.com/photos/97823772@N02/11819002925/ Sketch] of a talk Mat Todd gave about the project at the Sanger Institute/EBI in January 2014.<br>
The project is [http://www.thesaturdaypaper.com.au/life/2014/03/08/freeing-the-business-science/1394197200#.UxpFBF7byY4 the subject of a feature article] in the new Australian newspaper, The Saturday Paper.<br>
OSM is featured in International Innovation's issue on [http://www.internationalinnovation.com/build/wp-content/uploads/2014/07/p49-51_Matthew_Todd_Intl_Innovation_129_Research_Media.pdf Parasites of Poverty] alongside other developments from WHO/TDR and MMV. (file also archived [http://malaria.ourexperiment.org/osdd_malaria_shared/14665/Feature_on_OSM_in_International_Innovation_Parasites_of_Poverty_2014.html here]).
[http://www.sydgram.nsw.edu.au/files/sgsmagazine/SGSmagazine_iss1_Winter2015.pdf Article] (PDF, p36) in the winter newsletter of Sydney Grammar describing their involvement in the Open Source Malaria Consortium's research. The boys did some real research that can be read about in [http://figshare.com/articles/Open_Source_Malaria_2015/1513845 their reports].
===General Resources for Malaria===
[http://www.worldcommunitygrid.org/research/gfam/overview.do The Go Fight Against Malaria Scripps/IBM computing project]<br>
[http://www.thesynapticleap.org/malaria/community The Synaptic Leap malaria community]<br>
[http://www.thesynapticleap.org/malaria/community The Synaptic Leap malaria community]<br>
[http://bit.ly/OSDDcompounds List of available compounds on the open malaria project]<br>
[http://www.mendeley.com/groups/1846251/osddmalaria/ Mendeley group].
[http://twitter.com/#!/OSDDMalaria The OSDD Malaria Twitter Feed]<br>
[http://usefulchem.wikispaces.com/malaria The Usefulchem Malaria Project]<br>
[http://usefulchem.wikispaces.com/malaria The Usefulchem Malaria Project]<br>
[http://www.worldcommunitygrid.org/research/gfam/overview.do The Go Fight Against Malaria Scripps/IBM computing project]<br>
If you want to cut to the technical details, here is a [[short guide to using the Electronic Lab Notebook]]


'''Papers Describing Open Malaria Data Sets'''<br>
===Papers Most Relevant to Open Source Malaria===
[http://dx.doi.org/10.1021/ml200135p Original description of the GSK TCAMS set]<br>
[http://dx.doi.org/10.1021/ml200135p Original description of the GSK TCAMS set]<br>
[http://pubs.acs.org/doi/abs/10.1021/ml2001517 Evaluation of GSK TCMAS Cyclopropyl Carboxamides]<br>
[http://pubs.acs.org/doi/abs/10.1021/ml2001517 Evaluation of GSK TCMAS Cyclopropyl Carboxamides]<br>
[http://www.cell.com/chemistry-biology/retrieve/pii/S1074552112000178#Summary Article calling for more collaboration on global phenotypic screening]<br>
[http://www.cell.com/chemistry-biology/retrieve/pii/S1074552112000178#Summary Article calling for more collaboration on global phenotypic screening]<br>
[http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062906 PLoS ONE paper on MMV's Malaria Box]
[http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0117150 An Open Source Business Model for Malaria]


'''Articles About the Project'''<br>
===Miscellaneous Malaria-related Links===
[http://www.highlighthealth.org/open-science/open-source-drug-discovery-for-malaria/ Article by Walter Jessen on Highlight Health 2.0]<br>
[http://sydney.edu.au/news/science/397.html?newscategoryid=63&newsstoryid=8775 Feature on our first meeting at the University of Sydney]<br>


'''OSDD Malaria Meeting, Sydney, February 2012'''<br>
[http://www.nytimes.com/2013/07/16/science/a-low-tech-mosquito-deterrent.html?_r=1& Electric fans for mosquito control?]<br>
Planning notes may be viewed and edited here: [[OSDDMalaria:OSDD Malaria Meeting Sydney 2012 | OSDD Malaria Meeting Sydney 2012]].<br>
Promising series: The [http://pubs.acs.org/doi/abs/10.1021/jm401760c 2,4-diaminothienopyrimidines] possessing a core similar to OSM Series 3.
Meeting Summary, including links to talks, [http://www.thesynapticleap.org/node/390 here].<br>
Article about the meeting from Neil Saunders [http://nsaunders.wordpress.com/2012/05/11/my-day-out-at-osddmalaria/ here].<br>

Latest revision as of 09:02, 19 June 2017

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Outputs of the Open Source Malaria Project

Open Source Drug Discovery – A Limited Tutorial, M. N. Robertson, P. M. Ylioja, A. E. Williamson, M. Woelfle, M. Robins, K. A. Badiola, P. Willis, P. Olliaro, T. N. C. Wells and M. H. Todd, Parasitology 2014, 141, 148-157 Paper Altmetric Data
First published project data set
Master List of Chemical Compounds made

Non-publication/data Outputs

Open Source Drug Discovery for Malaria Conference, Sydney, February 2012 (Articles about this meeting: 1, 2)

April 2014 Newsletter

Short guide to using the Electronic Lab Notebook

May 2017 Flyer made for conference distribution

Articles/Features about Open Source Malaria

Alice's TedX talk, "Breaking Good" Paper from December 2013 describing OSM, comparing it with other initiatives such as the Bradner lab and containing a discussion of other meta-aspects of open drug discovery
Launch of Series 4
MMV interview with Mat Todd about open drug discovery
Article by Walter Jessen on Highlight Health 2.0
Guardian Innovations in Malaria
Development of the Website
An Example of Open Source Drug Discovery
Feature in the Guardian about open source drug discovery for malaria with separate discussion of the terminology "open source" when referring to drug discovery.
Sketch of a talk Mat Todd gave about the project at the Sanger Institute/EBI in January 2014.
The project is the subject of a feature article in the new Australian newspaper, The Saturday Paper.
OSM is featured in International Innovation's issue on Parasites of Poverty alongside other developments from WHO/TDR and MMV. (file also archived here).

Article (PDF, p36) in the winter newsletter of Sydney Grammar describing their involvement in the Open Source Malaria Consortium's research. The boys did some real research that can be read about in their reports.

General Resources for Malaria

The Go Fight Against Malaria Scripps/IBM computing project
The Synaptic Leap malaria community
Mendeley group. The Usefulchem Malaria Project

Papers Most Relevant to Open Source Malaria

Original description of the GSK TCAMS set
Evaluation of GSK TCMAS Cyclopropyl Carboxamides
Article calling for more collaboration on global phenotypic screening
PLoS ONE paper on MMV's Malaria Box An Open Source Business Model for Malaria

Miscellaneous Malaria-related Links

Electric fans for mosquito control?
Promising series: The 2,4-diaminothienopyrimidines possessing a core similar to OSM Series 3.