OpenSourceMalaria:GSK Triazolourea Singleton

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The proposed synthesis for this compound is below:
The proposed synthesis for this compound is below:
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[[Image:3synthesis.png|thumb|center|450px|Proposed synthesis for the above compound]]
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[[Image:3synthesisupdate.png|thumb|center|450px|Proposed synthesis for the above compound]]
Step 3 in particular needs attention and since this is an open project, anyone can contribute to improving this synthesis. The following, from (insert citation) is a possible alternative. Any input is greatly appreciated.
Step 3 in particular needs attention and since this is an open project, anyone can contribute to improving this synthesis. The following, from (insert citation) is a possible alternative. Any input is greatly appreciated.
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===References===
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Yasuda, N.; Nagakura, T.; Yamazaki, K.; Yoshikawa, S.; Okuda, T.; Ikuta, H.; Koyanagi, M. ( Eisai Co., Ltd.). Preparation of N-carbamoylazoles as dipeptidyl peptidase IV inhibitors. European Patent 1 258 480 A1, 2002; SciFinder Scholar AN 2002:886010 (accessed 2/3/2012).

Revision as of 08:30, 7 February 2012

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GSK Triazolourea Singleton

The triazolourea singleton has the following structure:

GSK Triazolourea Singleton: TCMDC 134395
GSK Triazolourea Singleton: TCMDC 134395

(detail goes here)

The proposed synthesis for this compound is below:

Proposed synthesis for the above compound
Proposed synthesis for the above compound

Step 3 in particular needs attention and since this is an open project, anyone can contribute to improving this synthesis. The following, from (insert citation) is a possible alternative. Any input is greatly appreciated.


References

Yasuda, N.; Nagakura, T.; Yamazaki, K.; Yoshikawa, S.; Okuda, T.; Ikuta, H.; Koyanagi, M. ( Eisai Co., Ltd.). Preparation of N-carbamoylazoles as dipeptidyl peptidase IV inhibitors. European Patent 1 258 480 A1, 2002; SciFinder Scholar AN 2002:886010 (accessed 2/3/2012).

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