OpenSourceMalaria:Other GSK Series Under Consideration
Other GSK Series Under Consideration
The team have focused on the synthesis and evaluation of two series (the aryl pyrroles and aminothienopyrimidines) to date. The focus of the project could change quite rapidly following the receipt of new biological data (for highly active or inactive compounds). This page highlights other GSK compounds from the TCAMS data that look attractive.
Citations for exact structure search: DOI:10.1021/ml200135p – GSK Paper on Open Innovation WO 1994-GB1409 – Preparation of anti-atherosclerotic diaryl compound, The Wellcome Foundation Atherosclerosis – The clogging or hardening of arteries or blood vessels caused by plaques (accumulations of fatty deposits, usually cholesterol
InChi Search: No hits on Google
Citations for sub-structure search: WO 2000-EP1224 – Preparation of phenyl and pyridinyl derivatives as NK-1 receptor antagonists, 2 F. Hoffmann La Roche Neurokinin 1 (NK), Antagonists – Novel class of medication possessing antidepressant, anxiolytic and antiemetic action ComGenex Compound (Scheme 2)