OSDDMalaria:OSDD Malaria Paper 1

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Open Source Drug Discovery for Malaria - Highly Potent Compounds Derived from the GSK Arylpyrrole Set

Vicky Avery
Felix Calderon
Sandra Duffy
Javier Gamo
Zoe Hungerford, School of Chemistry, The University of Sydney, NSW 2006, Australia
James Pham
Stuart Ralph
Matthew H. Todd, School of Chemistry, The University of Sydney, NSW 2006, Australia
Paul Willis
Paul Ylioja, School of Chemistry, The University of Sydney, NSW 2006, Australia

Additional authors - add alphabetically if you contribute something substantial. Please include some public place you can be contacted, e.g. a G+ account.

The licence for this page is CC BY 3.0

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Introduction

Possible background to include: lead-oriented synthesis paper (tenuous) and decline of R&D efficiency paper (good).

Synthesis

Evaluation

Conclusions

Acknowledgements

Experimental Details for Novel Compounds

Identities of compounds are here

The original lab notebook entries and data can be found here

Experimental Details for Biological Evaluation

Description of the biological evaluation can be found here

Supporting Information Section

Insert details for known compounds here.

References

(Use PLoS style - see Gamo et al for an example, or the official guidelines are here. Arrange references below in alphabetical order of first author)

  • Gamo FJ, Sanz LM, Vidal J, de Cozar C, Alvarez E et al (2010) Thousands of chemical starting points for antimalarial lead identification. Nature 465: 305-310 (DOI: 10.1038/nature09107)