OSDDMalaria:GSK Triazolourea Singleton
GSK Triazolourea Singleton
The triazolourea singleton has the following structure:
(detail goes here)
The proposed synthesis for this compound is below:
Step 3 in particular needs attention and since this is an open project, anyone can contribute to improving this synthesis. The following, from (insert citation) is a possible alternative. Any input is greatly appreciated.
Yasuda, N.; Nagakura, T.; Yamazaki, K.; Yoshikawa, S.; Okuda, T.; Ikuta, H.; Koyanagi, M. ( Eisai Co., Ltd.). Preparation of N-carbamoylazoles as dipeptidyl peptidase IV inhibitors. European Patent 1 258 480 A1, 2002; SciFinder Scholar AN 2002:886010 (accessed 2/3/2012).