OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

• Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
• Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

• To get on the listserve:

go to the following web site:

http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio

follow instructions for subscribing

• To send out your paper

Send an e-mail to 'oncobioATohsu.edu' with your paper attached

• When and where we meet

MacHall 2136

Thursdays noon-1 PM

Lunch provided by KCI

• Organizer contact information:

Rosie Sears-searsr@ohsu.edu

Charlie Lopez- lopezc@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

• Scheduling In Progress

Date	Presenters	Topic	Links & Comments
9/29/2011	Charlie Lopez	Organization
10/6/2011	xxxxxxxxxx	CANCEL	xxxxxxxxxx
10/13/2011	Xiaoli Zhang	Oncogenic PIK3CA-driven mammary tumors frequently recur via PI3K pathway–dependent and PI3K pathway–independent mechanisms	PI3KCA mechanisms
10/20/2011	Rosie Sears	Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis	Goetz 2009
10/27/2011	Katy Van Hook	Competative RNA	Karreth (2011)
11/3/2011	Mushui Dai	A Critical Role for Noncoding 5S rRNA in Regulating Mdmx Stability. Mol Cell. 2011 Sep 16;43(6):1023-32.	http://www.sciencedirect.com/science/article/pii/S109727651100640X
11/10/2011	Charlie Lopez	CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans	science 2011 Beatty
11/17/2011	canceled
11/24/2011	xxxxxxxxxx	THANKSGIVING, NO JOURNAL CLUB	xxxxxxxxxx
12/1/2011	Aaron Wortham	The Eph-Receptor A7 is a Soluble Tumor Suppressor for Follicular Lymphoma	Oricchio E et al 2011 Cell
12/8/2011	Myron Peto
12/15/2011	Chuck Pham Jr	Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells	http://www.mendeley.com/research/efficient-delivery-liposomemediated-mgmtsirna-reinforces-cytotoxity-temozolomide-gbminitiating-cells/
1/5/2012	Tim Butler
1/12/2012	Jared Fischer	Single-molecule transcript counting of stem-cell markers in the mouse intestine.	http://www.nature.com/ncb/journal/v14/n1/full/ncb2384.html
1/19/2012	Yulong Su	The Metabolic Regulator ERRa, a Downstream Target of HER2/IGF-1R, as a Therapeutic Target in Breast Cancer.	http://www.cell.com/cancer-cell/abstract/S1535-6108(11)00318-7
1/26/2012	Yuangang Liu	An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor	Opitz C et al 2011 Nature
2/2/2012	Mahnaz Janghorban
2/9/2012	Tiffany DeVine
2/16/2012	Jason Link
2/23/2012	Ellen Langer
3/1/2012	Aaron Jacobs	BRCA1 RING Function Is Essential for Tumor Suppression but Dispensable for Therapy Resistance	http://www.sciencedirect.com/science/article/pii/S1535610811004387
3/8/2012	Vince Bicocca	TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cancers	[1]
3/15/2012	Gordon Shore, Ph.D.	Regulation of cell death by the Bcl-2 family member Mcl-1	Vollum seminar, M1441
3/22/2012	John Oyer	Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia	[2]
4/5/2012
4/12/2012	Stacey Lin	The translational landscape of mTOR signalling steers cancer initiation and metastasis	http://www.nature.com/nature/journal/vaop/ncurrent/full/nature10912.html
4/19/2012	Juan Liang	Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer	Duncan (2012)
4/26/2012	Jeff Wu	Metastasis of tumor cells is enhanced by downregulation of Bit1. PLoS One.	[3]
5/3/2012	Arthur Edwards
5/10/2012	Xiaoxin Sun
5/17/2012	Nathalie Javidi-Sharifi
5/24/2012	Nichole Owen
5/31/2012	Zhiping Wang
6/7/2012	Kishore Challagundla