OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by KCI
:Lunch provided by KCI
*Organizer contact information:  
*Organizer contact information:  
: Rosie Sears-searsr@ohsu.edu
: Mushui Dai-daim@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu
: David Qian-qianzh@ohsu.edu


==Member Labs and Affiliations==
==Member Labs and Affiliations==
Line 50: Line 51:


|--
|--
|9/27/2012
|09/29/2015
|Rosalie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/4/2012
|10/6/2015
|Brittany Allen-Petersen
|Marilynn Chow
|Tumourmicro-environment elicits innate resistance to RAF inhibitors through HGF secretion
|
|[http://www.nature.com/nature/journal/v487/n7408/full/nature11183.html Straussman et al]
|
|--
|--
|10/11/2012
|10/13/2015
|Ellen Langer
|Kevin Watanabe-Smith
|A restricted cell population propagates glioblastoma growth after chemotherapy
|
|[http://openwetware.org/images/3/3a/Chen_Nature_2012.pdf Chen, et al] Additional vivo detection papers [http://www.ncbi.nlm.nih.gov/pubmed/22854777 1] [http://www.ncbi.nlm.nih.gov/pubmed/22855427 2]
|
|--
|--
|10/18/2012
|10/20/2015
|Yulong Su
|David Edwards
|Transcriptional Amplification in Tumor Cells with Elevated c-Myc;
|
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412010574 Lin 2012]
[http://www.sciencedirect.com/science/article/pii/S0092867412011014 Nie 2012]
|--
|--
|10/25/2012
|10/27/2015
|****CANCELLED****  Dr. Charles Lopez
|Xiaoxin Sun
| Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
|
|[http://openwetware.org/images/a/a5/Nature11156.pdf Misale at. al] [http://openwetware.org/images/3/33/Nature11156-s1.pdf supp. info]
|
|--  
|--  
|11/1/2012
|11/3/2015
|Asia Mitchell
|Ben Doron
|Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412004199]
|
|--
|11/10/2015
|Erica Goddard
|
|
|--
|11/17/2015
|Lilli Klug
|
|
|--
|11/24/2015
|Ryan Lane
|
|
|--
|12/01/2015
|Chelsea Jenkins
|
|
|--
|--
|11/8/2012
|12/08/2015
|Yuhan Wang
|Xiaoming Ouyang
|"Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Melanoma"
|
|[http://openwetware.org/images/4/4e/Journal_Club_paper-5hmc.pdf]
|
|--
|12/15/2015
|Shannon Lindahl
|
|
|--
|--
|11/15/2012
|12/22/2015
|Tyler Risom
|NO JC
|Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
|
| [http://openwetware.org/images/8/85/PI3K_and_Parp_1.full.pdf Ashish et. al.] [http://openwetware.org/images/8/82/PI3K_and_Parp_2.full.pdf Yasir et al]
|
|--
|--
|11/22/2012
|12/29/2015
|xxxxxxxxxx
|NO JC
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|11/29/2012
|1/5/2016
|Dr. Swarnali Acharyya, a CDB/Knight faculty candidate seminar
|Baotong Xie
|
|
|
|
|--
|--
|12/6/2012
|1/12/2016
|Marilynn Chow
|Kevin Watanabe-Smith
|Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression
|
|[http://openwetware.org/images/1/1d/2012_Oncogene_Pagliuca_et_al.pdf Pagliuca et al] [http://openwetware.org/images/3/3f/2012_Oncogene_Pagliuca_et_al_Supp.pdf supplement]
|  
|--
|--
|1/10/2013
|1/19/2016
|Lilli Welch
|David Edwards
|
|
|
|
|--
|--
|1/17/2013
|1/26/2016
|Spencer Watson
|Erica Goddard
|Mitochondrial dynamics regulates migration and invasion of breast cancer cells
|
|[http://openwetware.org/images/4/4b/Onc2012494a.pdf]
|  
|--
|--
|1/24/2013
|2/2/2016
|Ping Wang
|Lilli Klug
|Oncogenic Kras-Induced GM-CSF Projection Promotes the Development of Pancreatic Neoplasia
|
|[http://www.ncbi.nlm.nih.gov/pubmed/22698407] [http://www.ncbi.nlm.nih.gov/pubmed/22698406]
|
|--
|--
|1/31/2013
|2/09/2016
|Aaron Wortham
|Marilynn Chow
|Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
|
|[http://openwetware.org/images/5/51/Luga_V_et_al_Cell_2012.pdf Luga V et al Cell 151, 1542-1556 (2012)]
|
|--
|--
|2/7/2013
|2/16/2016
|Jeff Wu
|Qiuchen Guo
|MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrinsubunits
|
| [http://www.nature.com/ncb/journal/v14/n6/pdf/ncb2491.pdf]
|
|--
|--
|2/14/2013
|2/23/2016
|Tiffany Devine
|Chelsea Jenkins
|The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites
|
|[http://openwetware.org/images/3/3c/Gao_Cell_2012_BMP_inhibitor_coco_reactivates_BCC_at_lung_met_sites.pdf]
|
|--
|--
|2/21/2013
|3/1/2016
|Ellie Juarez
|Xiaoming Ouyang
|Poly(beta-aminoester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo Molecular Cancer Therapeutics
|
|[http://openwetware.org/images/b/bd/Gene_Therapy_JC_and_class.pdf]
|
|--
|--
|2/28/2013
|3/08/2016
|Tim Butler
|Timothy Carey
|tumor heterogeneity, focusing mostly on a recent science paper (Kreso 2013) which shows serially passages clones responding differently to chemotherapy
|
|[http://openwetware.org/images/0/09/Science-2013-Kreso-543-8.pdf Kreso 2013][http://openwetware.org/images/2/25/Gerlinger_2012%2C_Intratumor_Heterogeneity_multiregion_sequencing.pdf Gerlinger 2012]
|
|--
|--
|3/7/2013
|3/15/2016
|Toni West
|Tyler Risom
|Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
|
|[http://openwetware.org/images/c/c3/Schwitalla_S_et_al_Cell_152%2C_25-38_%282013%29.pdf Schwitalla S et al Cell 152, 25-38 (2013)]
|
|--
|--
|3/14/2013
|3/22/2016
|Jared Fischer
|Canceled, spring break
|Intestinal label-retaining cells are secretory precursors expressing Lgr5
|
|[http://openwetware.org/images/0/09/Nature11965%281%29.pdf]
|
|--
|--
|3/21/2013
|3/29/2016
|Mushui Dai
|Krishna Chauhan
|Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence.
|
|[http://openwetware.org/images/5/57/2013_SRSF1_L5_p53_MC.pdf]
|
|--
|--
|4/4/2013
|4/5/2016
|Nathalie Javidi-Sharifi
|Ben Doron
|Tumor Stem Cells Generate Vasculature
|
|[http://openwetware.org/images/2/25/Gsc_vasculature_hutchinson_comment_nature_2011.pdf] [http://openwetware.org/images/1/17/Gsc_pericytes_cheng_cell_2013_incl_supp.pdf]
|
|--
|--
|4/11/2013
|4/12/2016
|Amy Farrell
|Yulong Su
|Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
|
|[http://www.sciencedirect.com/science/article/pii/S1535610813000433 Stefan Eser, et al]
|
|--
|--
|4/18/2013
|4/19/2016
|Trevor Levin
|Shannon Lindahl
|DNA damage foci formation around double strand breaks and regulation of NHEJ and HR repair mechanisms
|
|[http://openwetware.org/images/5/59/Zimmermann2013_53BP1_Rif1_DSBRepair.pdf Zimmerman][http://openwetware.org/images/b/ba/Virgilio2013_Rif1_DNA_Breaks_IG_Switching.pdf Virgilio][http://openwetware.org/images/7/72/Kukas2013_Rif1_Perspective.pdf Kukas]
|
|--
|--
|4/25/2013
|4/26/2016
|Kevin Watanabe-Smith
|Yingxiao Chen
|"Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models"
|
|[http://openwetware.org/images/5/56/Corcoran_2013_Synthetic_Lethality_in_KRAS_mutant_cancer.pdf] [http://openwetware.org/images/6/68/Supplemental_-_Corcoran_2013.pdf]
|
|--
|--
|5/2/2013
|5/3/2016
|Stacey Lin
|Canceled---research week
|Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion
|
|[http://openwetware.org/images/a/ac/Li_and_Hanahan.pdf]
|--
|--
|5/9/2013
|5/10/2016
|Juan Liang
|Qiuchen Guo
|Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
|
|[http://openwetware.org/images/0/0e/2012_Cance_Cell_Inhibition_of_RNA_Polymerase_I_as_a_Therapeutic_Strategy.pdf]
|
|--
|--
|5/16/201
|5/17/2016
|Xiaoxin Sun
|Yulong Su
|Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
|
|[http://openwetware.org/images/5/5f/Cancer_journal_club_paper.pdf]
|
|--
|--
|5/23/2013
|5/24/2016
|Dr. Charles Lopez
|Young Me Yoon
|CANCELED DUE TO RESEARCH WEEK
|
|
|
|--
|--
|5/30/2013
|5/31/2016
|Mahnaz Janghorban
|
|Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
|
|[http://openwetware.org/images/b/b2/Loss_of_FBP1_by_Snail-Mediated_Repression_Provides_Metabolic_Advantages_in_Basal-like_Breast_Cancer.pdf Dong et al]
|
|--
|--
|6/6/2013
|6/07/2016
|Marcus Calkins
|
|"The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation"
|
|
|}
|}
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Revision as of 11:39, 13 January 2016

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu
David Qian-qianzh@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
09/29/2015 Organization
10/6/2015 Marilynn Chow
10/13/2015 Kevin Watanabe-Smith
10/20/2015 David Edwards
10/27/2015 Xiaoxin Sun
11/3/2015 Ben Doron
11/10/2015 Erica Goddard
11/17/2015 Lilli Klug
11/24/2015 Ryan Lane
12/01/2015 Chelsea Jenkins
12/08/2015 Xiaoming Ouyang
12/15/2015 Shannon Lindahl
12/22/2015 NO JC
12/29/2015 NO JC
1/5/2016 Baotong Xie
1/12/2016 Kevin Watanabe-Smith
1/19/2016 David Edwards
1/26/2016 Erica Goddard
2/2/2016 Lilli Klug
2/09/2016 Marilynn Chow
2/16/2016 Qiuchen Guo
2/23/2016 Chelsea Jenkins
3/1/2016 Xiaoming Ouyang
3/08/2016 Timothy Carey
3/15/2016 Tyler Risom
3/22/2016 Canceled, spring break
3/29/2016 Krishna Chauhan
4/5/2016 Ben Doron
4/12/2016 Yulong Su
4/19/2016 Shannon Lindahl
4/26/2016 Yingxiao Chen
5/3/2016 Canceled---research week
5/10/2016 Qiuchen Guo
5/17/2016 Yulong Su
5/24/2016 Young Me Yoon
5/31/2016
6/07/2016
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