OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by KCI
:Lunch provided by KCI
*Organizer contact information:  
*Organizer contact information:  
: Rosie Sears-searsr@ohsu.edu
: Mushui Dai-daim@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu
: David Qian-qianzh@ohsu.edu


==Member Labs and Affiliations==
==Member Labs and Affiliations==
Line 50: Line 51:


|--
|--
|9/27/2012
|09/30/2014
|Rosalie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/4/2012
|10/7/2014
|Tiffany DeVine
|
|
|--
|10/14/2014
|Brittany Allen-Petersen
|Brittany Allen-Petersen
|Tumourmicro-environment elicits innate resistance to RAF inhibitors through HGF secretion
|
|[http://www.nature.com/nature/journal/v487/n7408/full/nature11183.html Straussman et al]
|--
|--
|10/11/2012
|10/21/2014
|Yulong Su
|
|
|--
|10/28/2014
|Canceled
|
|--
|11/4/2014
|Ben Doron
|
|
|--
|11/11/2014
|Ellen Langer
|Ellen Langer
|A restricted cell population propagates glioblastoma growth after chemotherapy
|
|[http://openwetware.org/images/3/3a/Chen_Nature_2012.pdf Chen, et al] Additional vivo detection papers [http://www.ncbi.nlm.nih.gov/pubmed/22854777 1] [http://www.ncbi.nlm.nih.gov/pubmed/22855427 2]
|
|--
|--
|10/18/2012
|11/18/2014
|Yulong Su
|Canceled
|Transcriptional Amplification in Tumor Cells with Elevated c-Myc;
|
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
|  
|[http://www.sciencedirect.com/science/article/pii/S0092867412010574 Lin 2012]
[http://www.sciencedirect.com/science/article/pii/S0092867412011014 Nie 2012]
|--
|--
|10/25/2012
|11/25/2014
|****CANCELLED****  Dr. Charles Lopez
| Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
|[http://openwetware.org/images/a/a5/Nature11156.pdf Misale at. al] [http://openwetware.org/images/3/33/Nature11156-s1.pdf supp. info]
|--
|11/1/2012
|Asia Mitchell
|Asia Mitchell
|Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412004199]
|
|--
|--
|11/8/2012
|12/02/2014
|Yuhan Wang
|Erica Goddard
|"Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Melanoma"
|
|[http://openwetware.org/images/4/4e/Journal_Club_paper-5hmc.pdf]
|
|--
|--
|11/15/2012
|12/09/2014
|Tyler Risom
|Aaron Wortham
|Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
|
| [http://openwetware.org/images/8/85/PI3K_and_Parp_1.full.pdf Ashish et. al.] [http://openwetware.org/images/8/82/PI3K_and_Parp_2.full.pdf Yasir et al]
|
|--
|--
|11/22/2012
|12/16/2014
|xxxxxxxxxx
|Tim Butler
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|11/29/2012
|12/23/2014
|Dr. Swarnali Acharyya, a CDB/Knight faculty candidate seminar
|NO JC
|
|
|
|
|--
|--
|12/6/2012
|12/30/2014
|Marilynn Chow
|NO JC
|Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression
|
|[http://openwetware.org/images/1/1d/2012_Oncogene_Pagliuca_et_al.pdf Pagliuca et al] [http://openwetware.org/images/3/3f/2012_Oncogene_Pagliuca_et_al_Supp.pdf supplement]
|
|--
|--
|1/10/2013
|1/6/2015
|Lilli Welch
|Ellie Juaret
|
|
|
|
|--
|--
|1/17/2013
|1/13/2015
|Spencer Watson
|Lilli Klug
|Mitochondrial dynamics regulates migration and invasion of breast cancer cells
|
|[http://openwetware.org/images/4/4b/Onc2012494a.pdf]
|  
|--
|--
|1/24/2013
|1/20/2015
|Ping Wang
|Shannon Lindahl
|Oncogenic Kras-Induced GM-CSF Projection Promotes the Development of Pancreatic Neoplasia
|
|[http://www.ncbi.nlm.nih.gov/pubmed/22698407] [http://www.ncbi.nlm.nih.gov/pubmed/22698406]
|
|--
|--
|1/31/2013
|1/27/2015
|Aaron Wortham
|Marilynn Cho
|Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
|
|[http://openwetware.org/images/5/51/Luga_V_et_al_Cell_2012.pdf Luga V et al Cell 151, 1542-1556 (2012)]
|  
|--
|--
|2/7/2013
|2/3/2015
|Jeff Wu
|Chelsea Jenkins
|MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrinsubunits
|
| [http://www.nature.com/ncb/journal/v14/n6/pdf/ncb2491.pdf]
|
|--
|--
|2/14/2013
|2/10/2015
|Tiffany Devine
|Amber Bannon
|The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites
|
|[http://openwetware.org/images/3/3c/Gao_Cell_2012_BMP_inhibitor_coco_reactivates_BCC_at_lung_met_sites.pdf]
|
|--
|--
|2/21/2013
|2/17/2015
|Ellie Juarez
|David Edwards
|Poly(beta-aminoester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo Molecular Cancer Therapeutics
|
|[http://openwetware.org/images/b/bd/Gene_Therapy_JC_and_class.pdf]
|
|--
|--
|2/28/2013
|2/24/2015
|Tim Butler
|Courtney Betts
|tumor heterogeneity, focusing mostly on a recent science paper (Kreso 2013) which shows serially passages clones responding differently to chemotherapy
|
|[http://openwetware.org/images/0/09/Science-2013-Kreso-543-8.pdf Kreso 2013][http://openwetware.org/images/2/25/Gerlinger_2012%2C_Intratumor_Heterogeneity_multiregion_sequencing.pdf Gerlinger 2012]
|
|--
|--
|3/7/2013
|3/3/2015
|Toni West
|Canceled
|Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
|
|[http://openwetware.org/images/c/c3/Schwitalla_S_et_al_Cell_152%2C_25-38_%282013%29.pdf Schwitalla S et al Cell 152, 25-38 (2013)]
|
|--
|--
|3/14/2013
|3/10/2015
|Jared Fischer
|Kevin Watanabe-Smith
|Intestinal label-retaining cells are secretory precursors expressing Lgr5
|
|[http://openwetware.org/images/0/09/Nature11965%281%29.pdf]
|
|--
|--
|3/21/2013
|3/17/2015
|Mushui Dai
|Stacy Lin
|Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence.
|
|[http://openwetware.org/images/5/57/2013_SRSF1_L5_p53_MC.pdf]
|
|--
|--
|4/4/2013
|3/24/2015
|Nathalie Javidi-Sharifi
|Canceled, spring break
|Tumor Stem Cells Generate Vasculature
|
|[http://openwetware.org/images/2/25/Gsc_vasculature_hutchinson_comment_nature_2011.pdf] [http://openwetware.org/images/1/17/Gsc_pericytes_cheng_cell_2013_incl_supp.pdf]
|
|--
|--
|4/11/2013
|3/31/2015
|Amy Farrell
|Tyler Rison
|Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
|
|[http://www.sciencedirect.com/science/article/pii/S1535610813000433 Stefan Eser, et al]
|
|--
|--
|4/18/2013
|4/7/2015
|Trevor Levin
|Qiuchen Guo
|DNA damage foci formation around double strand breaks and regulation of NHEJ and HR repair mechanisms
|
|[http://openwetware.org/images/5/59/Zimmermann2013_53BP1_Rif1_DSBRepair.pdf Zimmerman][http://openwetware.org/images/b/ba/Virgilio2013_Rif1_DNA_Breaks_IG_Switching.pdf Virgilio][http://openwetware.org/images/7/72/Kukas2013_Rif1_Perspective.pdf Kukas]
|
|--
|--
|4/25/2013
|4/14/2015
|Kevin Watanabe-Smith
|Xiaoming Ouyang
|"Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models"
|
|[http://openwetware.org/images/5/56/Corcoran_2013_Synthetic_Lethality_in_KRAS_mutant_cancer.pdf] [http://openwetware.org/images/6/68/Supplemental_-_Corcoran_2013.pdf]
|
|--
|--
|5/2/2013
|4/21/2015
|Stacey Lin
|NO JC-AACR meeting
|Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion
|
|[http://openwetware.org/images/a/ac/Li_and_Hanahan.pdf]
|
|--
|--
|5/9/2013
|4/28/2015
|Juan Liang
|Erin Wiedmeier
|Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
|
|[http://openwetware.org/images/0/0e/2012_Cance_Cell_Inhibition_of_RNA_Polymerase_I_as_a_Therapeutic_Strategy.pdf]
|
|--
|--
|5/16/201
|5/5/2015
|Xiaoxin Sun
|Canceled---research week
|Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
|
|
|--
|--
|5/23/2013
|5/12/2015
|Dr. Charles Lopez
|Canceled
|
|
|
|
|--
|--
|5/30/2013
|5/19/2015
|Mahnaz Janghorban
|Mahnaz Janghorban
|
|
|
|
|--
|--
|6/6/2013
|5/26/2015
|Marcus Calkins
|
|
|
|--
|6/2/2015
|Spencer Watson
|
|
|--
|6/09/2015
|
|
|
|
|}
|}
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Revision as of 12:41, 11 May 2015

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu
David Qian-qianzh@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
09/30/2014 Organization
10/7/2014 Tiffany DeVine
10/14/2014 Brittany Allen-Petersen
10/21/2014 Yulong Su
10/28/2014 Canceled
11/4/2014 Ben Doron
11/11/2014 Ellen Langer
11/18/2014 Canceled
11/25/2014 Asia Mitchell
12/02/2014 Erica Goddard
12/09/2014 Aaron Wortham
12/16/2014 Tim Butler
12/23/2014 NO JC
12/30/2014 NO JC
1/6/2015 Ellie Juaret
1/13/2015 Lilli Klug
1/20/2015 Shannon Lindahl
1/27/2015 Marilynn Cho
2/3/2015 Chelsea Jenkins
2/10/2015 Amber Bannon
2/17/2015 David Edwards
2/24/2015 Courtney Betts
3/3/2015 Canceled
3/10/2015 Kevin Watanabe-Smith
3/17/2015 Stacy Lin
3/24/2015 Canceled, spring break
3/31/2015 Tyler Rison
4/7/2015 Qiuchen Guo
4/14/2015 Xiaoming Ouyang
4/21/2015 NO JC-AACR meeting
4/28/2015 Erin Wiedmeier
5/5/2015 Canceled---research week
5/12/2015 Canceled
5/19/2015 Mahnaz Janghorban
5/26/2015
6/2/2015 Spencer Watson
6/09/2015
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