OHSU Knight Cancer Institute Research Groups:OCI Cancer Journal Club: Difference between revisions

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*When and where we meet
*When and where we meet
:MacHall 2136
:MacHall 2136
:Thursdays noon-1 PM
:Tuesdays noon-1 PM
:Lunch provided by KCI
:Lunch provided by KCI
*Organizer contact information:  
*Organizer contact information:  
: Rosie Sears-searsr@ohsu.edu
: Mushui Dai-daim@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu
: Charlie Lopez- lopezc@ohsu.edu


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|--
|--
|9/27/2012
|10/1/2013
|Rosalie Sears
|
|Organization
|Organization
|
|
|--
|--
|10/4/2012
|10/8/2013
|Brittany Allen-Petersen
|Mahnaz Janghorban
|Tumourmicro-environment elicits innate resistance to RAF inhibitors through HGF secretion
|
|[http://www.nature.com/nature/journal/v487/n7408/full/nature11183.html Straussman et al]
|
|--
|--
|10/11/2012
|10/15/2013
|Ellen Langer
|Xiaoxin Sun
|A restricted cell population propagates glioblastoma growth after chemotherapy
|
|[http://openwetware.org/images/3/3a/Chen_Nature_2012.pdf Chen, et al] Additional vivo detection papers [http://www.ncbi.nlm.nih.gov/pubmed/22854777 1] [http://www.ncbi.nlm.nih.gov/pubmed/22855427 2]
|--
|--
|10/18/2012
|10/22/2013
|Yulong Su
|Yulong Su
|Transcriptional Amplification in Tumor Cells with Elevated c-Myc;
|
c-Myc Is a Universal Amplifier of Expressed Genes in Lymphocytes and Embryonic Stem Cells
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412010574 Lin 2012]
[http://www.sciencedirect.com/science/article/pii/S0092867412011014 Nie 2012]
|--
|--
|10/25/2012
|10/29/2013
|****CANCELLED****  Dr. Charles Lopez
| Stacey Lin
| Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
|
|[http://openwetware.org/images/a/a5/Nature11156.pdf Misale at. al] [http://openwetware.org/images/3/33/Nature11156-s1.pdf supp. info]
|--  
|--  
|11/1/2012
|11/5/2013
|Asia Mitchell
|
|Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks
|
|[http://www.sciencedirect.com/science/article/pii/S0092867412004199]
|
|--
|--
|11/8/2012
|11/12/2013
|Yuhan Wang
|Marilynn Chow
|"Loss of 5-Hydroxymethylcytosine is an Epigenetic Hallmark of Melanoma"
|
|[http://openwetware.org/images/4/4e/Journal_Club_paper-5hmc.pdf]
|
|--
|--
|11/15/2012
|11/19/2013
|Tyler Risom
|Michael Verga
|Combining a PI3K Inhibitor with a PARP Inhibitor Provides an Effective Therapy for BRCA1-Related Breast Cancer
|
| [http://openwetware.org/images/8/85/PI3K_and_Parp_1.full.pdf Ashish et. al.] [http://openwetware.org/images/8/82/PI3K_and_Parp_2.full.pdf Yasir et al]
|  
|--
|--
|11/22/2012
|11/26/2013
|xxxxxxxxxx
|Kevin Watanabe-Smith
|THANKSGIVING, NO JOURNAL CLUB
|
|xxxxxxxxxx
|
|--
|--
|11/29/2012
|12/3/2013
|Dr. Swarnali Acharyya, a CDB/Knight faculty candidate seminar
|Tim Butler
|
|
|
|
|--
|--
|12/6/2012
|12/10/2013
|Marilynn Chow
|Brittany Allen-Petersen
|Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression
|
|[http://openwetware.org/images/1/1d/2012_Oncogene_Pagliuca_et_al.pdf Pagliuca et al] [http://openwetware.org/images/3/3f/2012_Oncogene_Pagliuca_et_al_Supp.pdf supplement]
|
|--
|12/17/2013
|Aaron Wortham
|The Naked Mole Rat and Cancer: What we can learn from (one of) nature's ugliest creatures
|
|--
|--
|1/10/2013
|12/24/2013
|Lilli Welch
|Canceled
|
|
|
|
|--
|--
|1/17/2013
|12/31/2013
|Spencer Watson
|Canceled
|Mitochondrial dynamics regulates migration and invasion of breast cancer cells
|
|[http://openwetware.org/images/4/4b/Onc2012494a.pdf]
|
|--
|--
|1/24/2013
|1/7/2014
|Ping Wang
|
|Oncogenic Kras-Induced GM-CSF Projection Promotes the Development of Pancreatic Neoplasia
|
|[http://www.ncbi.nlm.nih.gov/pubmed/22698407] [http://www.ncbi.nlm.nih.gov/pubmed/22698406]
|
|--
|--
|1/31/2013
|1/14/2014
|Aaron Wortham
|Chelsea Jenkins
|Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration
|
|[http://openwetware.org/images/5/51/Luga_V_et_al_Cell_2012.pdf Luga V et al Cell 151, 1542-1556 (2012)]
|  
|--
|--
|2/7/2013
|1/21/2014
|Jeff Wu
|Juan Liang
|MYC suppresses cancer metastasis by direct transcriptional silencing of αv and β3 integrinsubunits
|
| [http://www.nature.com/ncb/journal/v14/n6/pdf/ncb2491.pdf]
|
|--
|--
|2/14/2013
|1/28/2014
|Tiffany Devine
|Charlie Gast
|The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites
|
|[http://openwetware.org/images/3/3c/Gao_Cell_2012_BMP_inhibitor_coco_reactivates_BCC_at_lung_met_sites.pdf]
|  
|--
|--
|2/21/2013
|2/4/2014
|Ellie Juarez
|Ellie Juarez
|Poly(beta-aminoester) nanoparticle-delivery of p53 has activity against small cell lung cancer in vitro and in vivo Molecular Cancer Therapeutics
|
|[http://openwetware.org/images/b/bd/Gene_Therapy_JC_and_class.pdf]
|
|--
|2/11/2014
|Tiffany DeVine
|
|
|--
|2/18/2014
|Tyler Risom
|
|
|--
|2/25/2014
|Amy Farrell
|
|
|--
|3/4/2014
| Asia Mitchell
|
|
|--
|--
|2/28/2013
|3/11/2014
|Tim Butler
|Spencer Watson
|tumor heterogeneity, focusing mostly on a recent science paper (Kreso 2013) which shows serially passages clones responding differently to chemotherapy
|
|[http://openwetware.org/images/0/09/Science-2013-Kreso-543-8.pdf Kreso 2013][http://openwetware.org/images/2/25/Gerlinger_2012%2C_Intratumor_Heterogeneity_multiregion_sequencing.pdf Gerlinger 2012]
|
|--
|--
|3/7/2013
|3/18/2014
|Toni West
|Zip Feng
|Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties
|
|[http://openwetware.org/images/c/c3/Schwitalla_S_et_al_Cell_152%2C_25-38_%282013%29.pdf Schwitalla S et al Cell 152, 25-38 (2013)]
|
|--
|--
|3/14/2013
|3/25/2014
|Jared Fischer
|Jason Link
|Intestinal label-retaining cells are secretory precursors expressing Lgr5
|
|[http://openwetware.org/images/0/09/Nature11965%281%29.pdf]
|
|--
|--
|3/21/2013
|4/1/2014
|Mushui Dai
|Hyunju Ryu
|Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence.
|
|[http://openwetware.org/images/5/57/2013_SRSF1_L5_p53_MC.pdf]
|
|--
|--
|4/4/2013
|4/8/2014
|Nathalie Javidi-Sharifi
|Xiaoming Ouyang
|Tumor Stem Cells Generate Vasculature
|
|[http://openwetware.org/images/2/25/Gsc_vasculature_hutchinson_comment_nature_2011.pdf] [http://openwetware.org/images/1/17/Gsc_pericytes_cheng_cell_2013_incl_supp.pdf]
|
|--
|--
|4/11/2013
|4/15/2014
|Amy Farrell
|Lilli Welch
|Selective Requirement of PI3K/PDK1 Signaling for Kras Oncogene-Driven Pancreatic Cell Plasticity and Cancer
|
|[http://www.sciencedirect.com/science/article/pii/S1535610813000433 Stefan Eser, et al]
|
|--
|--
|4/18/2013
|4/22/2014
|Trevor Levin
|Shannon Liudahl
|DNA damage foci formation around double strand breaks and regulation of NHEJ and HR repair mechanisms
|
|[http://openwetware.org/images/5/59/Zimmermann2013_53BP1_Rif1_DSBRepair.pdf Zimmerman][http://openwetware.org/images/b/ba/Virgilio2013_Rif1_DNA_Breaks_IG_Switching.pdf Virgilio][http://openwetware.org/images/7/72/Kukas2013_Rif1_Perspective.pdf Kukas]
|
|--
|--
|4/25/2013
|4/29/2013
|Kevin Watanabe-Smith
|Daniel Li
|"Synthetic Lethal Interaction of Combined BCL-XL and MEK Inhibition Promotes Tumor Regressions in KRAS Mutant Cancer Models"
|
|[http://openwetware.org/images/5/56/Corcoran_2013_Synthetic_Lethality_in_KRAS_mutant_cancer.pdf] [http://openwetware.org/images/6/68/Supplemental_-_Corcoran_2013.pdf]
|
|--
|--
|5/2/2013
|5/6/2014
|Stacey Lin
|David Edwards
|Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion
|
|[http://openwetware.org/images/a/ac/Li_and_Hanahan.pdf]
|--
|--
|5/9/2013
|5/13/2014
|Juan Liang
|
|Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53
|
|[http://openwetware.org/images/0/0e/2012_Cance_Cell_Inhibition_of_RNA_Polymerase_I_as_a_Therapeutic_Strategy.pdf]
|
|--
|--
|5/16/201
|5/20/2014
|Xiaoxin Sun
|Jeffrey Wu
|Restoring p53 Function in Human Melanoma Cells by Inhibiting MDM2 and Cyclin B1/CDK1-Phosphorylated Nuclear iASPP
|
|[http://openwetware.org/images/5/5f/Cancer_journal_club_paper.pdf]
|
|--
|--
|5/23/2013
|5/27/2014
|Dr. Charles Lopez
|
|CANCELED DUE TO RESEARCH WEEK
|
|
|
|--
|--
|5/30/2013
|6/3/2014
|Mahnaz Janghorban
|
|Loss of FBP1 by Snail-Mediated Repression Provides Metabolic Advantages in Basal-like Breast Cancer
|
|[http://openwetware.org/images/b/b2/Loss_of_FBP1_by_Snail-Mediated_Repression_Provides_Metabolic_Advantages_in_Basal-like_Breast_Cancer.pdf Dong et al]
|
|--
|--
|6/6/2013
|6/10/2014
|Marcus Calkins
|
|The eEF2 Kinase Confers Resistance to Nutrient Deprivation by Blocking Translation Elongation
|
|[http://openwetware.org/images/5/5c/EEF2_kinase_confers_resistance_to_ND.pdf]
|
|}
|}
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Revision as of 16:18, 27 November 2013

Equipped with his five senses, man explores the universe around him and calls the adventure Science. ~Edwin Powell Hubble, The Nature of Science, 1954

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Objectives of the OHSU Cancer Biology Journal Club

Cross-departmental journal club composed of students, postdocs, fellows and clinical and basic science faculty with shared interest in basic principles, emerging discoveries, and new therapeutic approaches in Cancer Biology. The goals of the meetings are to:

  • Critically evaluate new cutting edge literature on mechanisms underlying the development and maintenance of cancer to inform the development of new therapeutics. Papers should be paradigm shifting and set a backdrop for discussion into therapeutics facilitated by the clinical attendees.
  • Provide students, postdocs and fellows with training and interactions with faculty interested in Cancer Biology and emerging therapeutics

KCI CJC Information

Want to join us? All are invited!

  • To get on the listserve:
go to the following web site:
http://mailman.ohsu.edu/cgi-bin/mailman/listinfo/oncobio
follow instructions for subscribing
  • To send out your paper
Send an e-mail to 'oncobioATohsu.edu' with your paper attached
  • When and where we meet
MacHall 2136
Tuesdays noon-1 PM
Lunch provided by KCI
  • Organizer contact information:
Mushui Dai-daim@ohsu.edu
Charlie Lopez- lopezc@ohsu.edu

Member Labs and Affiliations

Lopez Lab Hem Onc

Sears Lab

Hoatlin Lab

Thayer Lab

Wong Lab

Lloyd Lab CROET

McCullough Lab CROET

Schedule

  • Scheduling In Progress
Date Presenters Topic Links & Comments
10/1/2013 Organization
10/8/2013 Mahnaz Janghorban
10/15/2013 Xiaoxin Sun
10/22/2013 Yulong Su
10/29/2013 Stacey Lin
11/5/2013
11/12/2013 Marilynn Chow
11/19/2013 Michael Verga
11/26/2013 Kevin Watanabe-Smith
12/3/2013 Tim Butler
12/10/2013 Brittany Allen-Petersen
12/17/2013 Aaron Wortham The Naked Mole Rat and Cancer: What we can learn from (one of) nature's ugliest creatures
12/24/2013 Canceled
12/31/2013 Canceled
1/7/2014
1/14/2014 Chelsea Jenkins
1/21/2014 Juan Liang
1/28/2014 Charlie Gast
2/4/2014 Ellie Juarez
2/11/2014 Tiffany DeVine
2/18/2014 Tyler Risom
2/25/2014 Amy Farrell
3/4/2014 Asia Mitchell
3/11/2014 Spencer Watson
3/18/2014 Zip Feng
3/25/2014 Jason Link
4/1/2014 Hyunju Ryu
4/8/2014 Xiaoming Ouyang
4/15/2014 Lilli Welch
4/22/2014 Shannon Liudahl
4/29/2013 Daniel Li
5/6/2014 David Edwards
5/13/2014
5/20/2014 Jeffrey Wu
5/27/2014
6/3/2014
6/10/2014
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